AOD Use Trajectories from Age 10 to 24: Multi-level Predictors, Health, and Behavioral Functioning, and Racial/ethnic Disparities

10 至 24 岁的 AOD 使用轨迹：多级预测因素、健康和行为功能以及种族/民族差异

• 批准号: 10088639
• 负责人: ELIZABETH J. D'AMICO
• 金额: $ 10万
• 依托单位: RAND CORPORATION
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-20 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10088639
• 关键词: Address; Administrative Supplement; Adolescence; Adult; Advertising; Affect; Age; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Area; Asians; Behavioral; Characteristics; Data; Data Set; Databases; Development; Drug usage; Economics; Education; Employment; Environment; Environmental Risk Factor; Epidemiology; Ethnic Origin; Ethnic group; Family; Female; Gender; Health; Hispanics; Illicit Drugs; Individual; Knowledge; Life; Link; Manuscripts; Marijuana; Measures; Medical Marijuana; Mental Health; Modeling; Neighborhoods; Occupational; Outcome; Parents; Pattern; Pharmaceutical Preparations; Population; Preparation; Prevention; Prevention strategy; Preventive Intervention; Psyche structure; Race; Reporting; Research; Research Support; Resistance; Risk Behaviors; Risk Factors; Role; Sampling; Schools; Self Efficacy; Sexual and Gender Minorities; Social Functioning; Subgroup; Surveys; Testing; Time; Tobacco; Work; Youth; alcohol and other drug; alcohol exposure; alcohol outlet density; alcohol related problem; alcohol research; cohort; density; driving under influence; early adolescence; emerging adulthood; ethnic difference; ethnic diversity; functional outcomes; health related quality of life; high risk sexual behavior; high school; interest; junior high school; longitudinal dataset; misuse of prescription only drugs; outcome prediction; parent project; peer; physical conditioning; protective factors; racial and ethnic; racial and ethnic disparities; racial difference; racial diversity; satisfaction; sex; sexual risk taking; sleep quality; social; social relationships; young adult

Summary/Abstract This administrative supplement responds to NOT-OD-20-032; Notice of Special Interest: Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations. Alcohol and other drug (AOD) use is a significant contributor to health and other functional disparities among sexual and gender minorities (SGMs). Some SGM individuals, particularly young adults, are more likely to use AOD compared to non-SGM peers. Prior work has reported on functional disparities across SGM and non-SGM young people, as well as differences in longitudinal patterns of AOD use across these groups. However, few studies have addressed how developmental trajectories of AOD use during adolescence and emerging adulthood may contribute to the emergence of disparities for SGM young adults, especially across multiple domains of functioning (e.g., academic and occupational functioning; social functioning). For example, very little is known regarding whether trajectories of AOD use during these important developmental periods may disproportionately affect outcomes for SGM individuals, or which domains of functioning may be differentially affected in young adulthood. Given that disparities may appear across a variety of different domains, it is crucial to assess AOD- related disparities across multiple domains of functioning to better understand how these negative outcomes may manifest for SGM individuals. Additionally, evidence suggests that subgroups of SGMs may differ with respect to patterns of AOD use, yet little research has addressed the emergence of AOD-related functional disparities within SGMs (e.g., by race/ethnicity). The proposed supplement research will utilize existing longitudinal data from the ongoing STudy of Racial diversity in AOD use during the Transition to Adulthood (STRATA; R01AA025848) to address these gaps. The rich, demographically diverse STRATA dataset will allow us to assess different types of AOD use (alcohol, marijuana, and other drugs) and outcomes across multiple domains with a large longitudinal sample. Study aims are: Aim 1. Examine trajectories of AOD use (i.e., alcohol, marijuana, and other illicit drugs; examined in separate models) over 11 years from early adolescence through young adulthood as predictors of functioning across multiple domains within SGM young adults: 1) risk behaviors (e.g., sexual risk-taking, delinquency), 2) physical health, 3) mental health, 4) social /relationship functioning, 5) academic functioning, and 6) occupational functioning; Aim 2. Determine whether disparities exist by assessing whether trajectories of AOD use are differentially associated with functioning in young adulthood for SGM versus non-SGM peers; and Aim 3. Within SGMs, assess whether AOD use trajectories differentially predict outcomes across racial/ethnic groups (i.e., racial/ethnic disparities within SGM) and sex/gender. Study findings will provide critical information on the emergence of AOD-related disparities for SGMs and can inform prevention and intervention efforts to reduce AOD-related harms.

Summary/Abstract This administrative supplement responds to NOT-OD-20-032; Notice of Special Interest: Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations. Alcohol and other drug (AOD) use is a significant contributor to health and other functional disparities among sexual and gender minorities (SGMs). Some SGM individuals, particularly young adults, are more likely to use AOD compared to non-SGM peers. Prior work has reported on functional disparities across SGM and non-SGM young people, as well as differences in longitudinal patterns of AOD use across these groups. However, few studies have addressed how developmental trajectories of AOD use during adolescence and emerging adulthood may contribute to the emergence of disparities for SGM young adults, especially across multiple domains of functioning (e.g., academic and occupational functioning; social functioning). For example, very little is known regarding whether trajectories of AOD use during these important developmental periods may disproportionately affect outcomes for SGM individuals, or which domains of functioning may be differentially affected in young adulthood. Given that disparities may appear across a variety of different domains, it is crucial to assess AOD- related disparities across multiple domains of functioning to better understand how these negative outcomes may manifest for SGM individuals. Additionally, evidence suggests that subgroups of SGMs may differ with respect to patterns of AOD use, yet little research has addressed the emergence of AOD-related functional disparities within SGMs (e.g., by race/ethnicity). The proposed supplement research will utilize existing longitudinal data from the ongoing STudy of Racial diversity in AOD use during the Transition to Adulthood (STRATA; R01AA025848) to address these gaps. The rich, demographically diverse STRATA dataset will allow us to assess different types of AOD use (alcohol, marijuana, and other drugs) and outcomes across multiple domains with a large longitudinal sample. Study aims are: Aim 1. Examine trajectories of AOD use (i.e., alcohol, marijuana, and other illicit drugs; examined in separate models) over 11 years from early adolescence through young adulthood as predictors of functioning across multiple domains within SGM young adults: 1) risk behaviors (e.g., sexual risk-taking, delinquency), 2) physical health, 3) mental health, 4) social /relationship functioning, 5) academic functioning, and 6) occupational functioning; Aim 2. Determine whether disparities exist by assessing whether trajectories of AOD use are differentially associated with functioning in young adulthood for SGM versus non-SGM peers; and Aim 3. Within SGMs, assess whether AOD use trajectories differentially predict outcomes across racial/ethnic groups (i.e., racial/ethnic disparities within SGM) and sex/gender. Study findings will provide critical information on the emergence of AOD-related disparities for SGMs and can inform prevention and intervention efforts to reduce AOD-related harms.