UAB Cardiovascular Disease Predoctoral Training Program in Biostatistics and Epidemiology

UAB心血管疾病生物统计学和流行病学博士前培训项目

• 批准号: 10088039
• 负责人: Paul Muntner
• 金额: $ 8.59万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10088039
• 关键词: Biometry; Cardiovascular Diseases; Epidemiology; Training Programs; pre-doctoral

The increasing availability of “big data” has transformed the training required to advance our understanding of the pathophysiology of cardiovascular disease (CVD), the identification of patient-level and public health approaches to prevent its occurrence and aspects of quality of care for patients with CVD and its risk factors. The goal of the proposed pre-doctoral National Heart, Lung, and Blood Institute T32 CVD training grant is to engage and empower biostatistics and epidemiology students with a strong foundation in both disciplines so they will be positioned to lead the design, conduct and analysis of the big data that are being collected in the 21st century. Located in the Southeastern US, an area with the highest heart disease death rates, the University of Alabama at Birmingham (UAB) has been at the forefront of CVD biostatistics and epidemiology research for over 25 years. The Departments of Biostatistics and Epidemiology are internationally recognized for leading randomized trial coordinating centers, serving as the coordinating center and field sites for epidemiology studies, conducting analyses of health insurance claims and electronic medical record data, and developing new methods for statistical genetics/genomics. For this T32 program, we are requesting funding for a total of 12 pre-doctoral trainees over the course of 5 years including 2 new trainees in each of years 1 through 3 and 3 new trainees in each of years 4 and 5. Trainees enrolled in the T32 program will receive a strong foundation in the pathophysiology and epidemiology of CVD, skills to design and conduct observational research, training on rigor and reproducibility in CVD research, familiarity with how real-world data are collected and analyzed, experience conducting big data analytics including omics data, grant writing experience, and networking opportunities within UAB and the larger scientific community of CVD researchers. Pre-doctoral trainees will complete activities that provide added value to their doctoral programs in biostatistics and epidemiology including didactic cross-training courses, a grant writing class and workshop, research immersions in three areas of big data, professional development workshops, and CVD seminars and a journal club. We have designed three workshops for this T32 grant including an 8-week summer training program on CVD, a high performance computing boot camp and a workshop on team science and communication. The training program’s capstone experience is a mentored research project resulting in a peer-reviewed manuscript. The program will be led by Drs. Hemant Tiwari and Paul Muntner, full professors in Biostatistics and Epidemiology, respectively, with strong mentoring records and program development experience. We have received the commitment from 14 primary mentors and 11 secondary mentors from the Departments of Biostatistics and Epidemiology. An additional 21 faculty members from across UAB have committed to serve as content mentors. The proposed pre-doctoral T32 Training Program will produce a cadre of biostatisticians and epidemiologists prepared to lead CVD research studies that address the priorities of NHLBI.

“大数据”的日益可用性已经改变了提高我们对知识的理解所需的培训。 心血管疾病（CVD）的病理生理学，患者水平和公共卫生的识别 预防其发生的方法以及CVD患者的护理质量及其危险因素。 拟议的博士前国家心脏，肺和血液研究所T32 CVD培训补助金的目标是 让生物统计学和流行病学的学生在这两个学科都有坚实的基础， 他们将被定位为领导设计，进行和分析正在收集的大数据， 21世纪世纪。位于美国东南部，心脏病死亡率最高的地区， 位于伯明翰的亚拉巴马大学（UAB）一直处于CVD生物统计学和流行病学的前沿 研究超过25年。生物统计学和流行病学系是国际公认的 领先的随机试验协调中心，作为协调中心和现场， 流行病学研究，对健康保险索赔和电子病历数据进行分析，以及 为统计遗传学/基因组学开发新方法。对于这个T32计划，我们正在申请资金， 在5年的课程中总共有12名博士前学员，包括每年2名新学员1 第四年和第五年每年有3名和3名新学员。参加T32计划的学员将获得 在CVD的病理生理学和流行病学方面有坚实的基础，能够设计和进行观察 研究，在CVD研究的严谨性和再现性的培训，熟悉如何真实世界的数据是 收集和分析，进行大数据分析的经验，包括组学数据，赠款写作 经验，并在UAB和CVD研究人员的更大的科学界的网络机会。 博士前学员将完成活动，提供附加值，他们的博士课程在生物统计学 和流行病学，包括教学交叉培训课程，赠款写作班和讲习班，研究 沉浸在大数据，专业发展研讨会，CVD研讨会和期刊三个领域 俱乐部我们为T32赠款设计了三个研讨会，包括为期8周的夏季培训计划， CVD，一个高性能计算靴子营地和团队科学和沟通研讨会。的 培训计划的顶点经验是一个指导研究项目，导致同行评审 手稿。该计划将由生物统计学教授Hemant Tiwari和Paul Muntner博士领导 和流行病学，分别与强大的指导记录和程序开发经验。我们 已收到来自以下部门的14名初级导师和11名中级导师的承诺： 生物统计学和流行病学。来自UAB的另外21名教师承诺为 作为内容导师拟议的博士前T32培训计划将培养一批生物统计学家 和流行病学家准备领导CVD研究，解决NHLBI的优先事项。