Beyond Black and White: Understanding Skin Tone as a Driver of Prepregnancy Cardiometabolic Health and Birth Outcomes

超越黑白：了解肤色是孕前心脏代谢健康和出生结果的驱动因素

• 批准号: 10133138
• 负责人: Jaime Catherine Slaughter-Acey
• 金额: $ 11.6万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10133138
• 关键词: Applications Grants; Attenuated; Beauty; Behavioral; Biomedical Research; Birth; Buffers; Cardiovascular Diseases; Chronic; Chronic stress; Colonialism; Color; Complex; Coronary Artery Risk Development in Young Adults Study; Criminal Justice; Data; Data Analyses; Discrimination; Economics; Empirical Research; Enrollment; Environment; Etiology; Exposure to; Failure; Female; Funding; Future; Geography; Goals; Health; Health Promotion; Health behavior; Heterogeneity; Hypertension; Image; Individual; Intervention; Life; Light; Literature; Longitudinal observational study; Low Birth Weight Infant; Mass Media; Mate Selections; Maternal Health; Maternal Mortality; Measures; Mediating; Metabolic Diseases; Nature; Outcome; Pathway interactions; Pattern; Periodicity; Plant Roots; Pregnancy; Pregnancy Outcome; Premature Birth; Proxy; Psychosocial Factor; Psychosocial Stress; Race; Recording of previous events; Research; Research Design; Research Methodology; Research Personnel; Resources; Risk; Risk Factors; Sampling; Self Perception; Shapes; Skin; Social Sciences; Societies; Socioeconomic Status; Stress; Structure; System; United States; United States National Institutes of Health; Variant; Woman; black women; black/white disparity; cardiometabolism; comorbidity; disorder risk; epidemiology study; gender difference; high risk; intersectionality; lens; maternal morbidity; men; neglect; optimism; perinatal health; perinatal outcomes; population health; prepregnancy; psychosocial; racial disparity; racial health disparity; racism; resilience; secondary analysis; skin color; socioeconomics; stress resilience; young adult

ABSTRACT—Despite an overall improvement in birth outcomes, racial disparities persist in the United States, (US). Moreover, Black women remain at a higher risk of having poor pregnancy outcomes even after controlling for traditional risk factors such socioeconomic status, health behaviors and chronic comorbidities. Though researchers have broadened their lens to look beyond behavioral and biomedical determinants of health and consider racism as a fundamental determinant, most of the biomedical research overlooks the multidimensional nature of race and remains focused on inter-group (Black vs. White) comparisons. Failure to rigorously and comprehensively consider the intersectionality of race and its intersection with skin color, a proxy for colorism, has limited our understanding of the etiology of racial health disparities, including those in perinatal health. To our knowledge there has been no research specifically aimed at understanding how skin color variation, independent of race, influences maternal prepregnancy health, psychosocial exposures, and subsequent pregnancy outcomes. The goal of this proposed project is to investigate the salience of skin color in relation to the prepregnancy cardiometabolic health and subsequent birth outcomes of Black women using data from the Coronary Artery Risk Development in Young Adults (CARDIA) Study. We will apply and intersectional lens to investigate the salience of skin color in relation to both in-group (e.g. within Blacks) and between-group (e.g. Black-White) heterogeneity. We will also explore skin color in relation to Black women’s psychosocial environment, since skin color may shape maternal health outcomes via 1) exposure to chronic and racism- related stress; 2) personal resilience resources (e.g. mastery and optimism) that may buffer against stress exposure; and 3) allocation of health promoting socioeconomic resources. This study provides a unique opportunity to consider how race, skin color, and socioeconomic status (SES) shape women’s prepregnancy cardiometabolic health, possible mediating psychosocial factors, and birth outcomes. Findings from this study will be used as preliminary data for a future NIH grant proposal to extend research on the intersectionality of race, skin color, and SES in relation to women’s pregnancy outcomes and cardiometabolic health.

摘要-尽管出生结果总体上有所改善，但美国的种族差异仍然存在， （US）.此外，黑人妇女即使在控制了怀孕后， 传统的风险因素，如社会经济地位，健康行为和慢性合并症。虽然 研究人员已经拓宽了他们的透镜，超越了行为和生物医学的健康决定因素， 考虑到种族主义是一个基本的决定因素，大多数生物医学研究忽视了多维的 种族的性质，并仍然侧重于组间（黑人与白色）的比较。未能严格和 全面考虑种族的交叉性及其与肤色的交叉性，肤色主义的代表， 限制了我们对种族健康差异的病因学的理解，包括围产期健康。到 据我们所知，还没有专门针对了解肤色变化的研究， 独立于种族，影响产妇孕前健康，心理社会暴露， 妊娠结局。这个项目的目标是研究肤色的显着性， 黑人妇女的孕前心脏代谢健康和随后的出生结果， 年轻人冠状动脉风险发展（CARDIA）研究。我们将应用交叉透镜， 调查肤色与组内（例如黑人）和组间（例如 黑白）异质性。我们还将探讨肤色与黑人妇女的社会心理的关系。 环境，因为肤色可能通过1）暴露于慢性和种族主义， 2）个人弹性资源（如掌握和乐观），可以缓冲压力 （3）促进健康的社会经济资源的分配。这项研究提供了一个独特的 有机会考虑种族，肤色和社会经济地位（SES）如何塑造女性的孕前 心脏代谢健康，可能的中介心理社会因素和出生结果。从这个研究结果 将被用作未来NIH拨款提案的初步数据，以扩展对以下交叉性的研究： 种族、肤色和社会经济地位与女性妊娠结局和心脏代谢健康的关系。