Multidisciplinary Approaches to Tumor Immunology

肿瘤免疫学的多学科方法

• 批准号: 10248383
• 负责人: Scott I. Abrams
• 金额: $ 13.55万
• 依托单位: ROSWELL PARK CANCER INSTITUTE CORP
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10248383
• 关键词: interdisciplinary approach; tumor immunology

PROJECT SUMMARY/ABSTRACT The overarching goals of the Tumor Immunology Training Program (TITP) at the Roswell Park Cancer Institute (RPCI) Graduate Division are to educate, train and prepare talented pre-doctoral students for a profession in cancer immunology research. Driven by significant advances in understanding how the immune system can be weaponized against cancer, future leaders in tumor immunology will not only be well-trained in the discipline, but also will have a strong appreciation of the potential translational impact to human cancer biology and therapy. The unique, cancer-focus within the TITP introduces trainees to an advanced didactic and conceptual cancer immunology educational paradigm that encapsulates knowledge spanning the continuum of basic science to clinical application. The uniqueness of this TITP is further enhanced by the integration of an academic environment comprised of diverse faculty concentrated within a prestigious NCI-designated Comprehensive Cancer Center. Trainees are exposed to a comprehensive portfolio of cancer-related topics that will be enhanced through a new “umbrella” academic curriculum starting in the fall of 2018. It is during the first year of study when trainees will select the tumor immunology-specific “track” and then conduct their doctoral research with TITP faculty with expertise in basic, translational, or clinical sciences. The primary mission of the training grant renewal is to support competitively selected students during their third and fourth years of study. The funds requested cover stipends and tuition for 4 pre-doctoral students per year. This funding is crucial to continue the upward trajectory experienced for nearly 15 years of NRSA support in the quality and diversity of pre-doctoral trainees focused on complex and challenging immunologic questions in cancer. NRSA-supported trainees are prepared for a competitive biomedical career through didactic lectures and concept-driven learning in tumor immunology and biology, grant writing and ethical conduct of research. After completing all formal course work, degree conferral is dependent upon passing the preliminary exam, fulfilling a first-authored publication requirement, and passing the dissertation defense reflecting the novel and original findings of the student's body-of-work. Trainees who complete this TITP will be well-versed in all major facets of tumor immunology and will have the solid foundation upon which to build cancer-focused careers, guided by a clear vision of its impact on human cancer biology and treatment.

项目摘要/摘要 罗斯威尔公园癌症研究所的肿瘤免疫学培训计划（TITP）的总体目标 （RPCI）研究生部门将为专业人士教育，培训和准备有才华的博士前学生 癌症免疫学研究。在理解免疫系统如何能够了解如何的驱动下 对癌症进行武器，肿瘤免疫学的未来领导者不仅会受到良好的训练 学科，但也将对人类癌症生物学的潜在翻译影响有很大的认识 和治疗。 TITP中独特的癌症焦点将训练引入了先进的教学和 概念性癌症免疫学教育范式封装了知识的连续性 临床应用的基础科学。通过整合一个TITP的独特性。 包括著名的NCI指定的潜水员教师的学术环境 综合癌症中心。受训人员接触到与癌症有关的综合主题组合 从2018年秋季开始，将通过新的“伞”学术课程来增强。 第一年学习的第一年，学员将选择特定于肿瘤免疫学特定的“轨迹”，然后进行他们的 具有基本，翻译或临床科学专业知识的TITP教师的博士研究。主要 培训授予申请的使命是在第三和第四名中支持竞争性选择的学生 多年学习。这些资金要求每年为4名博士前学生提供压力和学费。这 资金对于继续在近15年的NRSA支持中继续经历的向上轨迹至关重要。 博士前学员的质量和多样性，专注于复杂和挑战免疫问题的质量和多样性 癌症。 NRSA支持的学员已经为通过教学讲座做好了竞争性生物医学职业的准备 肿瘤免疫学和生物学中的概念驱动的学习，授予写作和研究道德行为。 完成所有正式课程工作后，学位会议取决于通过初步考试 满足了第一个著名的出版要求，并通过反映小说的论文辩护和 学生工作主体的原始发现。完成此TITP的学员将在所有专业中精通 肿瘤免疫学方面，将建立以癌症为中心的职业的坚实基础， 在明确的愿景中，其对人类癌症生物学和治疗的影响。