NLRP1 and obesity

NLRP1 与肥胖

• 批准号: nhmrc : 1142354
• 负责人: A/Pr Andrew Murphy
• 金额: $ 23.22万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Targeted Calls
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/nlrp1-obesity/1319680
• 关键词: NLRP1; obesity

Il-18 helps to prevent obesity and type 2 diabetes, however the process by which this cytokine is activated to prevent obesity is not known. We have now found the pathway that drives to this process. This project will seek to extend our observations to show how this can be targeted therapeutically to treat obesity and type 2 diabetes.

IL-18有助于预防肥胖和2型糖尿病，然而，这种细胞因子被激活以预防肥胖的过程尚不清楚。我们现在已经找到了推动这一过程的途径。这个项目将寻求扩大我们的观察范围，以显示如何在治疗上有针对性地治疗肥胖症和2型糖尿病。