Wearable Nanoelectronic Vapor Sensors for Transdermal Alcohol Monitoring

用于透皮酒精监测的可穿戴纳米电子蒸汽传感器

基本信息

  • 批准号:
    10255523
  • 负责人:
  • 金额:
    $ 41.86万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-08-10 至 2023-12-31
  • 项目状态:
    已结题

项目摘要

Project Summary In this Commercialization Readiness Pilot (CRP) Program project, Arborsense will develop field-ready wearable alcohol bio-monitors that are robust and comfortable to wear continuously while maintaining the functionality and performance demonstrated in Phase II, and conduct a field compliance study for 4 weeks to establish product- market fit. Excessive alcohol consumption is the fourth leading preventable cause of death in the US. Alcohol- related deaths have accelerated significantly in the past two decades as has the prevalence of other alcohol- related harms such as alcohol use disorder and alcohol-related liver disease. Arborsense’s wearable alcohol bio-monitor will address the unmet need for a continuous, convenient-to-use, and discreet device for monitoring alcohol consumption without discomfort or stigma. This will lead to better awareness and compliance with respect to alcohol use amongst the general public. Arborsense received an NSF Phase I SBIR grant (IIP-1548317) with which we demonstrated proof-of-concept graphene alcohol sensors and their feasibility in human volunteer tests. This led to an NIAAA Phase II SBIR grant (R44AA026119) that allowed us to build light, standalone, and wrist- worn sensor modules integrated with self-calibration electronics and Bluetooth transceiver to transmit data wirelessly to our custom Android app. In Phase II, we collaborated with the University of Michigan to validate these sensor modules in large scale human subject tests (82 human participants; more than 150 sensors tested in over 300 individual tests on multiple body locations). We have shown that our current modules can continuously and reliably detect drink events with peak BAC level >0.03% when benchmarked with legal grade breathalyzer and have very low false positives and low false negatives. In this CRP program, we will collaborate with Sundberg-Ferar (a Michigan based industrial design firm) and incorporate robustness, ergonomic refinements, and aesthetics to develop a rugged and high-fidelity system that will be utilized for a multi-week wear study through the University of Michigan. We will also engage with our strategic partners during the design process to incorporate features necessary for market acceptance. The successful performance of our bio- monitors in these real-world tests in terms of functionality and usability is a key milestone towards market approval and production development and will continue to provide investment momentum.
项目摘要 在这个商业化准备试点(CRP)项目中,Arborsense将开发现场就绪的可穿戴设备, 酒精生物监测器,耐用且舒适,可连续佩戴,同时保持功能性, 在第二阶段中展示性能,并进行为期4周的现场合规性研究,以确定产品- 市场契合度过量饮酒是美国第四大可预防的死亡原因。酒精- 在过去二十年中,与酒精相关的死亡率显著加快,其他酒精的流行率也是如此, 相关的危害,如酒精使用障碍和酒精相关的肝病。Arborsense的可穿戴酒精 生物监测器将解决对连续、易于使用和谨慎的监测设备的未满足的需求 饮酒没有不适或耻辱。这将导致更好的认识和遵守尊重 酒精在公众中的使用。Arborsense获得NSF第一阶段SBIR资助(IIP-1548317), 我们展示了石墨烯酒精传感器的概念验证及其在人类志愿者测试中的可行性。 这导致了NIAAA第二阶段SBIR赠款(R44 AA 026119),使我们能够建立轻,独立,和手腕- 与自校准电子设备和蓝牙收发器集成的磨损传感器模块,用于传输数据 在第二阶段,我们与密歇根大学合作, 这些传感器模块在大规模人类受试者测试中(82名人类参与者;测试了150多个传感器 在多个身体位置上的300多个单独测试中)。我们已经证明,我们目前的模块可以 当以法律的等级为基准时,连续可靠地检测具有峰值BAC水平>0.03%的饮用事件 呼吸测醉器,并具有非常低的假阳性和低假阴性。在这个CRP项目中,我们将合作 与Sundberg-Ferar(一家位于密歇根州的工业设计公司)合作, 改进和美学,以开发一个坚固耐用的高保真系统,将用于多个星期 穿研究通过密歇根大学。我们还将在设计过程中与我们的战略合作伙伴合作 过程,以纳入市场接受所需的功能。我们的生物- 显示器在这些实际测试中的功能和可用性是走向市场的一个关键里程碑 审批和生产开发,并将继续提供投资动力。

项目成果

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会议论文数量(0)
专利数量(1)

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Girish Kulkarni其他文献

Girish Kulkarni的其他文献

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{{ truncateString('Girish Kulkarni', 18)}}的其他基金

Rapid and non-invasive device for drug detection through sweat
通过汗液快速、非侵入性检测药物的装置
  • 批准号:
    10540571
  • 财政年份:
    2020
  • 资助金额:
    $ 41.86万
  • 项目类别:
Rapid and non-invasive device for drug detection through sweat
通过汗液快速、非侵入性检测药物的装置
  • 批准号:
    10544121
  • 财政年份:
    2020
  • 资助金额:
    $ 41.86万
  • 项目类别:
Rapid and non-invasive device for drug detection through sweat
通过汗液快速、非侵入性检测药物的装置
  • 批准号:
    10665052
  • 财政年份:
    2020
  • 资助金额:
    $ 41.86万
  • 项目类别:

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