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Chronic graft-versus-host disease

Chronic graft-versus-host disease
慢性移植物抗宿主病
批准号：
10262362
负责人：
Edward Cowen
金额：
$97.3万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10262362
关键词：
CalcinosisCase SeriesClinicalClinical TrialsCutaneousFunctional disorderImatinibInstitutesOutputPublicationsResearch PersonnelRisk FactorsRoleSkinSkin ManifestationsSpecialistSpecimenUnited States National Institutes of HealthWhole-Body Irradiationchronic graft versus host diseaseclinical centermultidisciplinarynovelskin disorder

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英文摘要
This effort continues to be very productive as evidenced by the yearly publication output related to GVHD, including publication of the Branch initiated imatinib clinical trial. In addition, I have made several important contributions to the identification of novel skin manifestations of cGVHD, as well as identified the role of total body irradiation as a risk factor for cGVHD. Current projects including ssRNA analysis of cutaneous GVHD specimens to better understand the pathophysiology of skin disease. Clinical projects including the first topical study of ruxolitinib for skin GVHD and a case series on cutaneous calcinosis in skin GVHD.
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