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Anakinra for neutrophilic pustular skin disease

Anakinra for neutrophilic pustular skin disease
阿那白滞素（Anakinra）治疗中性粒细胞性脓疱性皮肤病
批准号：
8938186
负责人：
Edward Cowen
金额：
$28.08万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8938186
关键词：
ClinicalCollaborationsDiseaseEnrollmentGoalsInterleukin-1LaboratoriesOutcomePET/CT scanPathway interactionsPatientsProtocols documentationPustular psoriasisSamplingSerumTherapeuticTissuesTreatment Protocolsanakinracardiovascular disorder riskdesignskin disorder

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英文摘要
To date, eight patients have enrolled on this treatment protocol. A goal of 25-30 patients has been established to determine if anakinra has efficacy for pustular neurtrophilic skin disease. In addition to the clinical outcomes, tissue and serum samples are being sent to the lab of Raphaela Goldbach-Mansky, Maria Morasso, Alison McBride, and Nehal Mehta in order to further investigate the biologic pathways responsible for pustular psoriasis, including risk of cardiovascular disease as assessed by PET/CT.
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