Penn+Plus Clinical Research Center

项目摘要/摘要 宾夕法尼亚大学下尿路系统预防临床中心 (宾夕法尼亚++CC)是一名多元化、经验丰富、忠诚和宝贵的成员 预防下尿路症状(PLUS)网络，展示一个杰出的团队 跨学科调查人员带来青少年和妇女骨盆健康方面的专业知识 保健、健康行为和预防科学、仪器开发和流行病学。我们 的独特之处在于我们对实施科学的关注和我们在 城乡交汇，受益于巨大而独特的 宾夕法尼亚大学的资源。在第一阶段，宾夕法尼亚++调查人员做出了重大贡献 到第一阶段的所有PLUS出版物和演示文稿。这包括发表的11篇文章 或在印刷中，提交了6份手稿，26份提交了国内和国际陈述 在第二阶段，为了加强我们与社区的接触，我们与 与宾夕法尼亚大学社区参与核心，将制定一个现实的计划，纳入 社区合作伙伴，并增加了新的团队成员作为联合调查员，Heather博士 Klusaritz和Terri Lipman，他们在基于社区的参与性研究方面拥有专业知识 方法：研究方法。我们提出了第二阶段工作的具体目标，以满足所有规定的需求 在RFA中，包括支持具有全国代表性的以人口为基础的大型队列研究 膀胱健康(目标1)，这是一个开发和验证评估膀胱的新工具的项目 青春期女孩和妇女的自我护理(目标2)，并试行以社区为基础的 促进膀胱健康计划(目标3)。

PROJECT SUMMARY/ABSTRACT The University of Pennsylvania Prevention of Lower Urinary Tract Systems Clinical Center (PENN+PLUS CC) is a diverse, experienced, committed and invaluable member of the Prevention of Lower Urinary Tract Symptoms (PLUS) Network, presenting an exceptional team of interdisciplinary investigators bringing expertise in adolescent and women’s pelvic health care, health behavior and prevention science, instrument development, and epidemiology. We are distinguished by our focus on implementation science and our unique location at the intersection of urban and rural areas and benefit from the significant and unique wealth of resources of UPenn. In Phase 1, the PENN+PLUS investigators made significant contributions to all PLUS publications and presentations during Phase 1. This includes 11 articles published or in press, 6 submitted manuscripts, and 26 refereed national and international presentations For Phase 2, to bolster the strength of our engagement with the community, we have partnered with the Penn Community Engagement Core, which will develop a realistic plan for inclusion of community partners, and have added new team members as Co-investigators, Drs Heather Klusaritz and Terri Lipman, who have expertise in community-based participatory research methods. We propose specific aims for Phase 2 efforts that address all of the needs stipulated in the RFA, including support for a nationally representative population-based large cohort study of bladder health (Aim 1), a project to develop and validate a novel tool for evaluating bladder self-care among adolescent girls and women (Aim 2), and pilot testing of a community-based bladder health promotion program (Aim 3).