Indigenous Trauma & Resilience Research Center

本土创伤

• 批准号: 10091058
• 负责人: Donald Keith Warne
• 金额: $ 211.5万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10091058
• 关键词: Address; Advisory Committees; Age; American Indians; Assimilations; Award; Basic Science; Behavioral; Biological; Centers of Research Excellence; Cessation of life; Chippewa; Chronic Disease; Collection; Communities; Community Outreach; Core Grant; Development; Enrollment; Ensure; Epigenetic Process; Faculty; Food; Funding; Funding Opportunities; Future; Goals; Grant; Health; Health Promotion; Human Subject Research; Indigenous; Individual; Infant Mortality; Interdisciplinary Study; Link; Mentors; Methods; Monoclonal Antibody R24; Native-Born; North Dakota; Outcome; Peer Review; Personal Satisfaction; Population; Post-Traumatic Stress Disorders; Poverty; Pregnancy; Principal Investigator; Publishing; Research; Research Assistant; Research Infrastructure; Research Personnel; Research Project Grants; Risk Factors; Sampling; Scholarship; Schools; Senior Scientist; Services; Social Conditions; Stress; Suicide; Teton Sioux Indian; Training; Training Activity; Translational Research; Trauma; Tribes; Turtles; Unemployment; United States National Institutes of Health; Universities; Work; academic program; addiction; allostatic load; base; career; community based participatory research; community engagement; emotional trauma; experience; faculty research; graduate student; health disparity; health inequalities; human subject; improved; indigenous community; infrastructure development; interest; intergenerational; member; perceived stress; programs; protective factors; psychological trauma; ranpirnase; resilience; skills; success; tribal community

OVERALL PROJECT ABSTRACT Indigenous populations experience significant trauma-related health disparities, including addiction, post- traumatic stress disorder, chronic diseases, infant mortality, and suicide. Many of these disparities are worse for American Indians (AIs) in the Dakotas. AI communities also contend with historical and intergenerational trauma from decades of traumatic losses and forced assimilation. Hence, we will establish the Indigenous Trauma & Resilience Research Center at UND to address the health impact of unresolved trauma and the protective factors of cultural connectedness and resilience. The Center will consist of three interrelated research projects—each led by an early career investigator and assisted by senior scientist mentors. Objectives: 1. Establish a nationally-recognized and acclaimed Indigenous Trauma & Resilience Research Center at UND with a goal to improve AI health and well-being. 2. Provide support and mentoring to the Project Leaders to enable future success in obtaining R01 funding. 3. Establish Administrative, Community Engagement & Outreach, and Human Subjects Cores that will support the Center and will provide services to strengthen research capacity to address Indigenous health. Methods: Three research projects include: (1) Historical trauma and resilience as a biological state and its association with the effects of the traditional Indigenous food chokeberry; (2) Impact of boarding school attendance on perceived stress, allostatic load and resilience; and (3) Stress and health in American Indian pregnancies. We will leverage existing assets at UND, including several Institutional Development Award (IDeA) programs. Mentoring will be provided to support the project leaders through an Administrative Core consisting of the Program Director/Principal Investigator (PD/PI), Internal and External Advisory Committees, and a group of high-level scientific Project Mentors. Each project leader will use community-based, participatory research principles and will complete the Tribal Community Engagement Training Module that was developed by the PD/PI. A Community Engagement & Outreach Core will be led by Dr. Melanie Nadeau of the Turtle Mountain Band of Chippewa Indians from ND. Cultural considerations for human subjects research and collection of biological samples will be supported by a Human Subjects Core that will provide technical assistance regarding research compliance and addressing cultural norms. Significant opportunities exist for meta-scholarship in which COBRE stakeholders will publish best and promising practices to support community-engaged human subjects research with Indigenous populations. The center will be sustainable and competitive for numerous other grant programs, including Research Project Grants (R01) and related funding.

总体项目摘要