A Training Program for Interdisciplinary Cancer Research

要求提供支助，以继续在哥伦比亚大学开展成功的癌症研究培训方案。 加州尔湾（UCI）。这个新更名的跨学科癌症研究培训计划（IDCR） 建立在40多年的博士生和博士后发展经验的基础上 成为科学领导者。随着癌症研究和治疗的性质不断演变， 我们培训计划的重点。我们强调跨学科的方法来推进知识， 癌症生物学和治疗，为学员提供一个高度协作的环境，包括教师 来自UCI五所不同学校的导师。课程强调对研究文献的批判性分析， 癌症和相关学科，最新的研究方法，以及对转化科学的关注， 随着治疗学和诊断学的发展我们共同提供的科学基础 提供的专业发展活动将培养一批训练有素的专家， 从学术界和工业界的Vantage位置成功地解决了癌症问题。程序 受益于UCI Chao家庭综合癌症中心（a NCI指定的综合癌症中心），UCI癌症研究所，研究生部，以及 其他校园办公室该计划提供了跨癌症连续体的研究机会， 从病因学到治疗学，包括来自生物科学，医学，药学学院的教师 以及药学、物理科学和工程学。有30个培训学院，每个 以癌症为中心的研究项目和校外资金我们请求支持四个博士后 和四名博士前实习生;一个额外的博士前职位将由我们的研究生部支持。 该计划由两名共同主任领导，他们都是具有杰出研究生产力记录的高级教师 和训练，以及合作的历史。在准备这次更新申请时，我们进行了一次 严格的自我评估与输入的学员，教师和外部顾问。这一过程使我们 实施一个修订后的计划，以满足当前UCI学员的具体需求。一个持续的元素 该计划将是一个严格和明确的课程设置（“癌症生物学A和B部分”，“临床 癌症基础科学家”），建立有关基础和临床/转化癌症研究的知识。 其他将继续进行的重要组成部分包括一年两次的项目务虚会、基础教育年度研讨会 癌症研究，并获得特殊的专业发展机会（根据 NIH-BEST奖，并继续与校园支持）。一个根本性的变化将是重新设计我们的期刊 俱乐部和研究进展会谈，以最大限度地与不同的培训教师互动，并扩大积极的 学习跨学科癌症研究方法。我们还将在程序中实施几项更改 管理，以提高教师的参与和优化辅导，评估和招聘。

Support is requested to continue a successful cancer research training program at the University of California, Irvine (UCI). This newly renamed Training Program for Interdisciplinary Cancer Research (IDCR) builds on a foundation of more than 40 years of experience developing PhD students and postdoctoral fellows to become scientific leaders. As the nature of cancer research and treatment have evolved, so has the focus of our training program. We emphasize interdisciplinary approaches to advance knowledge in cancer biology and treatment, offering trainees a highly collaborative environment that includes faculty mentors from five different Schools at UCI. Coursework emphasizes critical analysis of research literature in cancer and related disciplines, the most current research methods, and a focus on translational science such as the development of therapeutics and diagnostics. The scientific foundation we provide together with professional development activities offered will produce a cohort of well-trained experts armed to successfully attack the cancer problem from vantage points in both academia and industry. The Program benefits from outstanding institutional support from the UCI Chao Family Comprehensive Cancer Center (a NCI-designated comprehensive cancer center), the UCI Cancer Research Institute, Graduate Division, and other campus offices. The Program provides research opportunities across the cancer continuum from etiology to therapeutics, encompassing faculty from the Schools of Biological Sciences, Medicine, Pharmacy and Pharmaceutical Sciences, Physical Sciences, and Engineering. There are thirty training faculty, each with a cancer-focused research program and extramural funding. We request support for four postdoctoral and four predoctoral trainees; one additional predoctoral position will be supported by our Graduate Division. The Program is led two co-Directors, both senior faculty with outstanding records of research productivity and training, and a history of collaboration. In preparation for this renewal application, we have carried out a rigorous self-evaluation with input from trainees, faculty, and externaladvisors. This process has led us to implement a revised program that meets the specific needs of current UCI trainees. A continuing element of the Program will be a rigorous and well-defined set of courses (“Cancer Biology parts A and B”, "Clinical Cancer for Basic Scientists") that build knowledge about basic and clinical/translational cancer research. Other strong components that will continue are the biannual program retreat, the annual symposium in basic cancer research, and access to exceptional professional development opportunities (established under a NIH-BEST award and continuing with campus support). A fundamental change will be to redesign our journal clubs and research-in-progress talks to maximize interaction with diverse training faculty and expand active learning of interdisciplinary cancer research approaches. We will also implement several changes in program administration to increase faculty participation and to optimize mentoring, evaluation, and recruitment.