Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes

以数据为依据的分级护理 (DiSC) 可改善青少年艾滋病毒治疗结果

• 批准号: 10579767
• 负责人: Grace John-Stewart
• 金额: $ 29.97万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-06 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10579767
• 关键词: Adherence; Administrative Supplement; Adolescent; Adolescent and Young Adult; Adult; Age; Assessment tool; Biological Assay; Caregiver support; Caregivers; Caring; Childhood; Client; Client satisfaction; Clinic; Clinical; Cluster randomized trial; Consent; Data; Development; Educational workshop; Effectiveness; Effectiveness of Interventions; Enrollment; Ethics; Failure; Family; Frequencies; Funding; HIV; HIV Seropositivity; HIV-infected adolescents; Health Personnel; Health Services; Intensive Care; Intervention; Kenya; Mental Health Services; Modeling; Outcome; Participant; Patients; Policies; Prospective cohort; Research; Resources; Risk; Risk Assessment; Services; Testing; Treatment outcome; Viral; Viral Load result; Wait Time; Work; Workload; base; care outcomes; cofactor; cohort; design; effectiveness evaluation; effectiveness trial; follow-up; improved; improved outcome; insight; multidisciplinary; parent grant; primary outcome; programs; recruit; routine care; secondary outcome; standard of care; therapy development; tool; treatment as usual

ABSTRACT This administrative supplement requests funds to provide viral load assays for DiSC participants to optimize utility of stepped tool and to retain cluster a RCT design that includes viral suppression as an outcome. Our data- informed stepped care (DiSC) intervention assigns adolescents and young adults (AYA) in HIV care in Kenya to different intensities of health services according to their need. To assign AYA to specific services, health care workers use a risk assessment tool to identify AYA needing intensified care. They also identify AYA thriving in HIV care needing less intensive services to enable programs to appropriately allocate limited resources. Unfortunately, viral load supplies have been limited in Kenya resulting in absence of viral load assays for over a year for many AYA HIV care clients. We request budgetary support to cover viral load assays for participating AYA at two points: at enrollment into the trial to inform step allocation and at exit for secondary outcome of viral suppression. This will provide important insights on the effectiveness of the intervention and mechanisms of effectiveness and will add important value to the DiSC RCT. Scientific aims are unchanged.

摘要

项目成果

Data-informed stepped care to improve youth engagement in HIV care in Kenya: a protocol for a cluster randomised trial of a health service intervention.

• DOI: 10.1136/bmjopen-2022-062134
• 发表时间: 2022-10-31
• 期刊: BMJ OPEN
• 影响因子: 2.9
• 作者: Kohler, Pamela;Agot, Kawango;Njuguna, Irene N.;Dyer, Jessica;Badia, Jacinta;Jiang, Wenwen;Beima-Sofie, Kristin;Chhun, Nok;Inwani, Irene;Shah, Seema K.;Richardson, Barbra A.;Chaktoura, Nahida;John-Stewart, Grace
• 通讯作者: John-Stewart, Grace