Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes
Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes
批准号:
10579767
负责人:
Grace John-Stewart
金额:
$29.97万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
已结题
起止时间:
2022-04-06 至 2023-08-31
关键词:
AdherenceAdministrative SupplementAdolescentAdolescent and Young AdultAdultAgeAssessment toolBiological AssayCaregiver supportCaregiversCaringChildhoodClientClient satisfactionClinicClinicalCluster randomized trialConsentDataDevelopmentEducational workshopEffectivenessEffectiveness of InterventionsEnrollmentEthicsFailureFamilyFrequenciesFundingHIVHIV SeropositivityHIV-infected adolescentsHealth PersonnelHealth ServicesIntensive CareInterventionKenyaMental Health ServicesModelingOutcomeParticipantPatientsPoliciesProspective cohortResearchResourcesRiskRisk AssessmentServicesTestingTreatment outcomeViralViral Load resultWait TimeWorkWorkloadbasecare outcomescofactorcohortdesigneffectiveness evaluationeffectiveness trialfollow-upimprovedimproved outcomeinsightmultidisciplinaryparent grantprimary outcomeprogramsrecruitroutine caresecondary outcomestandard of caretherapy developmenttooltreatment as usual
中文摘要
点击翻译按钮获取中文摘要
英文摘要
ABSTRACT
This administrative supplement requests funds to provide viral load assays for DiSC participants to optimize
utility of stepped tool and to retain cluster a RCT design that includes viral suppression as an outcome. Our data-
informed stepped care (DiSC) intervention assigns adolescents and young adults (AYA) in HIV care in Kenya to
different intensities of health services according to their need. To assign AYA to specific services, health care
workers use a risk assessment tool to identify AYA needing intensified care. They also identify AYA thriving in
HIV care needing less intensive services to enable programs to appropriately allocate limited resources.
Unfortunately, viral load supplies have been limited in Kenya resulting in absence of viral load assays for over a
year for many AYA HIV care clients. We request budgetary support to cover viral load assays for participating
AYA at two points: at enrollment into the trial to inform step allocation and at exit for secondary outcome of viral
suppression. This will provide important insights on the effectiveness of the intervention and mechanisms of
effectiveness and will add important value to the DiSC RCT. Scientific aims are unchanged.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1136/bmjopen-2022-062134
发表时间:
2022-10-31
期刊:
BMJ OPEN
影响因子:
2.9
作者:
[Kohler, Pamela, Agot, Kawango, Njuguna, Irene N., Dyer, Jessica, Badia, Jacinta, Jiang, Wenwen, Beima-Sofie, Kristin, Chhun, Nok, Inwani, Irene, Shah, Seema K., Richardson, Barbra A., Chaktoura, Nahida, John-Stewart, Grace]
通讯作者:
John-Stewart, Grace
Drug, microbiome, and immune determinants of birth and neurodevelopmental outcomes in children with exposure to HIV infection
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批准号:10381032
-
项目类别:
-
资助金额:$431.95万
-
财政年份:2022
-
负责人:Grace John-Stewart
-
依托单位:
Administrative Core
-
批准号:10381033
-
项目类别:
-
资助金额:$65.21万
-
财政年份:2022
-
负责人:Grace John-Stewart
-
依托单位:
HEU outcomes: population-evaluation and screening strategies (HOPE)
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批准号:10645291
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项目类别:
-
资助金额:$66.35万
-
财政年份:2020
-
负责人:Grace John-Stewart
-
依托单位:
HEU outcomes: population-evaluation and screening strategies (HOPE)
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批准号:10661848
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项目类别:
-
资助金额:$67.01万
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财政年份:2020
-
负责人:Grace John-Stewart
-
依托单位:
HEU outcomes: population-evaluation and screening strategies (HOPE)
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批准号:10063773
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项目类别:
-
资助金额:$39.75万
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财政年份:2020
-
负责人:Grace John-Stewart
-
依托单位:
HEU outcomes: population-evaluation and screening strategies (HOPE)
-
批准号:10764153
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项目类别:
-
资助金额:$29.84万
-
财政年份:2020
-
负责人:Grace John-Stewart
-
依托单位:
Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes
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批准号:10252949
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项目类别:
-
资助金额:$92.87万
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财政年份:2018
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负责人:Grace John-Stewart
-
依托单位:
Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes
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批准号:10227279
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项目类别:
-
资助金额:$93.48万
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财政年份:2018
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负责人:Grace John-Stewart
-
依托单位:
Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes
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批准号:9923276
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项目类别:
-
资助金额:$15.36万
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财政年份:2018
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负责人:Grace John-Stewart
-
依托单位:
Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes
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批准号:10468750
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项目类别:
-
资助金额:$95.92万
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财政年份:2018
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负责人:Grace John-Stewart
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依托单位:
Infant immune mechanisms of HIV reservoir size and decay
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批准号:9395120
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项目类别:
-
资助金额:$77.88万
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财政年份:2017
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负责人:Grace John-Stewart
-
依托单位:
Infant immune mechanisms of HIV reservoir size and decay
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批准号:10200873
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项目类别:
-
资助金额:$66.92万
-
财政年份:2017
-
负责人:Grace John-Stewart
-
依托单位:
PrEP Adherence Among AGYW: A Multidimensional Evaluation
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批准号:10192772
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项目类别:
-
资助金额:$57.3万
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财政年份:2017
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负责人:Grace John-Stewart
-
依托单位:
Transitioning from Pediatric to Adult HIV Care in Kenya
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批准号:9205809
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项目类别:
-
资助金额:$34.76万
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财政年份:2016
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负责人:Grace John-Stewart
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依托单位:
Delivering PrEP in Pregnancy
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批准号:9912703
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项目类别:
-
资助金额:$65.31万
-
财政年份:2016
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负责人:Grace John-Stewart
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依托单位:
Evaluation of mHealth strategies to optimize adherence and efficacy of PMTCT/ART
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批准号:9060183
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项目类别:
-
资助金额:$66.43万
-
财政年份:2014
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负责人:Grace John-Stewart
-
依托单位:
Evaluation of mHealth strategies to optimize adherence and efficacy of PMTCT/ART
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批准号:8728688
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项目类别:
-
资助金额:$68.51万
-
财政年份:2014
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负责人:Grace John-Stewart
-
依托单位:
Hiv-1 Counseling and Testing for Children at Home (CATCH)
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批准号:8836566
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项目类别:
-
资助金额:$13.15万
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财政年份:2014
-
负责人:Grace John-Stewart
-
依托单位:
Evaluation of mHealth strategies to optimize adherence and efficacy of PMTCT/ART
-
批准号:8842162
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项目类别:
-
资助金额:$69.89万
-
财政年份:2014
-
负责人:Grace John-Stewart
-
依托单位:
Hiv-1 Counseling and Testing for Children at Home (CATCH)
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批准号:8749101
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项目类别:
-
资助金额:$24.19万
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财政年份:2014
-
负责人:Grace John-Stewart
-
依托单位:
海外基金