Genetic studies of homologous recombination deficiency in hispanic gastric cancer
Genetic studies of homologous recombination deficiency in hispanic gastric cancer
批准号:
10578426
负责人:
Luis Guillermo Carvajal Carmona
金额:
$5.91万
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-06-08 至 2024-05-31
关键词:
AddressAffectBRCA1 geneCDH1 geneCancer EtiologyCancer PatientCessation of lifeClinicalCountryDNADataDiagnosisDiseaseE-CadherinEarly DiagnosisEarly treatmentEtiologyFundingGene MutationGenesGeneticGenetic ResearchGenetic studyGenomicsGerm-Line MutationHispanicHispanic PopulationsIndividualInheritedLatinoLatino PopulationMalignant NeoplasmsMedicineMinorityModelingMolecularMutationNot Hispanic or LatinoPALB2 geneParentsPathway interactionsPatientsPatternPenetrancePopulationPrevalenceRAD51C geneResearchRiskRisk AssessmentRisk FactorsSNP arraySamplingSingle Nucleotide PolymorphismStatistical Data InterpretationStomach NeoplasmsTestingThe Cancer Genome AtlasTimeVariantWorkbasecancer genomecancer health disparitycancer riskcancer survivalcancer therapycohortdriver mutationearly onsetexome sequencinggastric cancer preventiongene repairhigh riskhomologous recombinationimprovedindividualized preventionmalignant stomach neoplasmmodel buildingmolecular phenotypemolecular subtypesmortalitymutation carriernovelparent grantpolygenic risk scorerisk variantscreening programsurvival disparitysurvival outcometumorwhole genome
中文摘要
工作范围
目的1:确定拉美裔胃癌患者候选单核苷酸多态性选择
并审查项目中多基因建模.ims的判别性准确性。
目的2:探讨生殖系单核苷酸多态与突变的关系
这些信号与影响胃分子亚型特征的因素有关
肿瘤。
英文摘要
Scope of Work
Aim 1: To identify candidate single nucleotide polymorphism selection in Hispanic gastric cancer patients
and review discriminatory accuracy for polygenic modeling.ims in the project.
Aim 2: To investigate the association of germline single nucleotide polymorphisms with mutation
signatures and which has association in affecting the molecular subtype characterization of gastric
tumors.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
University of California and UT Southwestern D-PDTC
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批准号:10733391
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项目类别:
-
资助金额:$106.11万
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财政年份:2023
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负责人:Luis Guillermo Carvajal Carmona
-
依托单位:
Admin Core
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批准号:10733392
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项目类别:
-
资助金额:$22.65万
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财政年份:2023
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Advancing gastric cancer precision medicine in Latinos through patient-derived modeling
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批准号:10733395
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项目类别:
-
资助金额:$31.79万
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财政年份:2023
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Preclinical studies of KRAS and EGFR mutations in lung cancer PDXs
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批准号:10582478
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项目类别:
-
资助金额:$20.0万
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财政年份:2022
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
UC Davis Multi-Disciplinary Cancer Research Training Program to Advance Precision Cancer Prevention and Care in Latin America.
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批准号:10438437
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项目类别:
-
资助金额:$27.0万
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财政年份:2022
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Bridges to Doctorate Program between Fresno State and UC Davis
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批准号:10674976
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项目类别:
-
资助金额:$27.4万
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财政年份:2020
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Bridges to Doctorate Program between Fresno State and UC Davis
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批准号:10223383
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项目类别:
-
资助金额:$32.38万
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财政年份:2020
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Bridges to Doctorate Program between Fresno State and UC Davis
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批准号:10024812
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项目类别:
-
资助金额:$12.36万
-
财政年份:2020
-
负责人:Luis Guillermo Carvajal Carmona
-
依托单位:
Bridges to Doctorate Program between Fresno State and UC Davis
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批准号:10454971
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项目类别:
-
资助金额:$26.88万
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财政年份:2020
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Development of Research And Writing Skills (DRAWS): A tool for broader assessment to enhance research and research training
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批准号:10393926
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项目类别:
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资助金额:$0.67万
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财政年份:2020
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
University of California Minority Patient-Derived Xenograft (PDX) Development and Trial Center (UCaMP) to Reduce Cancer Health Disparities
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批准号:10011077
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项目类别:
-
资助金额:$1.2万
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财政年份:2018
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负责人:Luis Guillermo Carvajal Carmona
-
依托单位:
Genetic studies of homologous recombination deficiency in hispanic gastric cancer
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批准号:10172867
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项目类别:
-
资助金额:$52.7万
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财政年份:2018
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负责人:Luis Guillermo Carvajal Carmona
-
依托单位:
Genetic studies of homologous recombination deficiency in hispanic gastric cancer
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批准号:10411392
-
项目类别:
-
资助金额:$7.26万
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财政年份:2018
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Genetic studies of homologous recombination deficiency in hispanic gastric cancer
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批准号:10425289
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项目类别:
-
资助金额:$38.08万
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财政年份:2018
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负责人:Luis Guillermo Carvajal Carmona
-
依托单位:
Genetic studies of homologous recombination deficiency in hispanic gastric cancer
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批准号:10524102
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项目类别:
-
资助金额:$1.11万
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财政年份:2018
-
负责人:Luis Guillermo Carvajal Carmona
-
依托单位:
University of California Minority Patient-Derived Xenograft (PDX) Development and Trial Center (UCaMP) to Reduce Cancer Health Disparities
-
批准号:9905142
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项目类别:
-
资助金额:$32.29万
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财政年份:2018
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
Dissecting gastric cancer clonality with genomic analyses and patient xenografts
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批准号:9188431
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项目类别:
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资助金额:$17.07万
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财政年份:2016
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负责人:Luis Guillermo Carvajal Carmona
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依托单位:
海外基金