西班牙裔胃癌同源重组缺陷的遗传学研究-猫眼课题宝

西班牙裔胃癌同源重组缺陷的遗传学研究

批准号：

10578426

负责人：

Luis Guillermo Carvajal Carmona

金额：

$5.91万

依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

依托单位国家：

美国

项目类别：

财政年份：

2018

资助国家：

美国

项目状态：

已结题

起止时间：

2018-06-08 至 2024-05-31

来源：

https://reporter.nih.gov/project-details/10578426

关键词：

Address Affect BRCA1 gene CDH1 gene Cancer Etiology Cancer Patient Cessation of life Clinical Country DNA Data Diagnosis Disease E-Cadherin Early Diagnosis Early treatment Etiology Funding Gene Mutation Genes Genetic Genetic Research Genetic study Genomics Germ-Line Mutation Hispanic Hispanic Populations Individual Inherited Latino Latino Population Malignant Neoplasms Medicine Minority Modeling Molecular Mutation Not Hispanic or Latino PALB2 gene Parents Pathway interactions Patients Pattern Penetrance Population Prevalence RAD51C gene Research Risk Risk Assessment Risk Factors SNP array Sampling Single Nucleotide Polymorphism Statistical Data Interpretation Stomach Neoplasms Testing The Cancer Genome Atlas Time Variant Work base cancer genome cancer health disparity cancer risk cancer survival cancer therapy cohort driver mutation early onset exome sequencing gastric cancer prevention gene repair high risk homologous recombination improved individualized prevention malignant stomach neoplasm model building molecular phenotype molecular subtypes mortality mutation carrier novel parent grant polygenic risk score risk variant screening program survival disparity survival outcome tumor whole genome

项目摘要

项目成果

Luis Guillermo Carvajal Carmona的其他基金

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中文摘要

翻译

工作范围目的1：确定西班牙裔胃癌患者的候选单核苷酸多态性选择和审查的判别准确性多基因建模。目的2：探讨生殖系单核苷酸多态性与基因突变的关系标签，并与影响胃粘膜上皮细胞的分子亚型特征有关。肿瘤的

英文摘要

Scope of Work Aim 1: To identify candidate single nucleotide polymorphism selection in Hispanic gastric cancer patients and review discriminatory accuracy for polygenic modeling.ims in the project. Aim 2: To investigate the association of germline single nucleotide polymorphisms with mutation signatures and which has association in affecting the molecular subtype characterization of gastric tumors.

期刊论文(1)

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会议论文

University of California and UT Southwestern D-PDTC

批准号：

10733391
项目类别：
资助金额：

$106.11万
财政年份：

2023
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Admin Core

批准号：

10733392
项目类别：
资助金额：

$22.65万
财政年份：

2023
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Advancing gastric cancer precision medicine in Latinos through patient-derived modeling

批准号：

10733395
项目类别：
资助金额：

$31.79万
财政年份：

2023
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Preclinical studies of KRAS and EGFR mutations in lung cancer PDXs

批准号：

10582478
项目类别：
资助金额：

$20.0万
财政年份：

2022
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

UC Davis Multi-Disciplinary Cancer Research Training Program to Advance Precision Cancer Prevention and Care in Latin America.

批准号：

10438437
项目类别：
资助金额：

$27.0万
财政年份：

2022
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Bridges to Doctorate Program between Fresno State and UC Davis

批准号：

10674976
项目类别：
资助金额：

$27.4万
财政年份：

2020
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

CALIFORNIA STATE UNIVERSITY FRESNO

Bridges to Doctorate Program between Fresno State and UC Davis

批准号：

10223383
项目类别：
资助金额：

$32.38万
财政年份：

2020
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

CALIFORNIA STATE UNIVERSITY FRESNO

Bridges to Doctorate Program between Fresno State and UC Davis

批准号：

10024812
项目类别：
资助金额：

$12.36万
财政年份：

2020
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

CALIFORNIA STATE UNIVERSITY FRESNO

Bridges to Doctorate Program between Fresno State and UC Davis

批准号：

10454971
项目类别：
资助金额：

$26.88万
财政年份：

2020
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

CALIFORNIA STATE UNIVERSITY FRESNO

Development of Research And Writing Skills (DRAWS): A tool for broader assessment to enhance research and research training

批准号：

10393926
项目类别：
资助金额：

$0.67万
财政年份：

2020
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

CALIFORNIA STATE UNIVERSITY FRESNO

University of California Minority Patient-Derived Xenograft (PDX) Development and Trial Center (UCaMP) to Reduce Cancer Health Disparities

批准号：

10011077
项目类别：
资助金额：

$1.2万
财政年份：

2018
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Genetic studies of homologous recombination deficiency in hispanic gastric cancer

批准号：

10411392
项目类别：
资助金额：

$7.26万
财政年份：

2018
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Genetic studies of homologous recombination deficiency in hispanic gastric cancer

批准号：

10172867
项目类别：
资助金额：

$52.7万
财政年份：

2018
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Genetic studies of homologous recombination deficiency in hispanic gastric cancer

批准号：

10425289
项目类别：
资助金额：

$38.08万
财政年份：

2018
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Genetic studies of homologous recombination deficiency in hispanic gastric cancer

批准号：

10524102
项目类别：
资助金额：

$1.11万
财政年份：

2018
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

University of California Minority Patient-Derived Xenograft (PDX) Development and Trial Center (UCaMP) to Reduce Cancer Health Disparities

批准号：

9905142
项目类别：
资助金额：

$32.29万
财政年份：

2018
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

Dissecting gastric cancer clonality with genomic analyses and patient xenografts

批准号：

9188431
项目类别：
资助金额：

$17.07万
财政年份：

2016
负责人：

Luis Guillermo Carvajal Carmona
依托单位：

UNIVERSITY OF CALIFORNIA AT DAVIS

海外基金