Core 2: Clinical Resource Core

摘要 阿尔茨海默病(AD)是对老年人健康的一大威胁，也是一场迫在眉睫的公共卫生灾难。 诊断和治疗方面所需的解决方案只有通过研究才能实现。我们对此的贡献 总体项目是为项目提供临床资源支持。这包括临床共识 诊断、系统神经心理测试结果、神经影像数据、研究质量获得的脑脊液 腰椎穿刺术和脑部尸检。 我们的核心将利用由斯坦福AD中心和 斯坦福大学尤德尔中心。其他样品也将由我们的长期合作伙伴道格博士提供 加州大学圣地亚哥分校广告中心的加拉斯科博士和班纳研究所的托马斯·比奇博士。《临床》 资源核心的具体目标是：1)一致的临床诊断和神经心理测试结果，2) 脑脊液样本和3)脑尸检 。

Abstract Alzheimer's disease (AD) is a major threat to health of older individuals and is a looming public health disaster. Needed solutions in diagnostics and therapeutics will come only through research. Our contribution to this overall project is to provide clinical resources to support the Projects. This includes consensus clinical diagnosis, systematic neuropsychological test results, neuroimaging data, CSF obtained by research quality lumbar puncture, and brain autopsy. Our Core will leverage existing clinical research infrastructure provided by the Stanford AD Center and the Stanford Udall Center. Additional samples also will be provided by our long-time collaborators, Dr. Doug Galasko from the UCSD AD Center, and Dr. Thomas Beach from Banner Research Institute. The Clinical Resource Core's Specific Aims are: 1) Consensus Clinical Diagnosis and Neuropsychological Test Results, 2) CSF Samples and 3) Brain Autopsy .