Northeast Node of the National Drug Abuse Clinical Trials Network
国家药物滥用临床试验网络东北节点
基本信息
- 批准号:10583143
- 负责人:
- 金额:$ 25.48万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-09-01 至 2025-02-28
- 项目状态:未结题
- 来源:
- 关键词:Accident and Emergency departmentAchievementAlcoholsArtificial IntelligenceAuthorization documentationBehavior TherapyBioinformaticsCannabisCaringClinicalClinical TreatmentClinical TrialsClinical Trials NetworkCommunicationCommunitiesCommunity HealthcareCommunity NetworksComplementDataData AnalyticsData ScienceDrug abuseExperimental DesignsFederally Qualified Health CenterFire - disastersFundingHIVHealth Services AccessibilityHealth behaviorHealthcareHuman immunodeficiency virus testIndividualInfrastructureInternationalJusticeLeadLeadershipLinkMaineMedicalMental HealthMental disordersNational Clinical Trials NetworkNational Institute of Drug AbuseNew HampshireOpioidPatientsPersonsPharmaceutical PreparationsPharmacy facilityPhenotypePoliciesPregnant WomenPrimary Health CareProviderPublicationsResearchResearch InfrastructureResearch MethodologyResearch PersonnelResourcesRoleRuralRural CommunityScienceSecuritySeriesStimulantStrategic PlanningSubstance Use DisorderSystemTechnologyTimeTobaccoTrainingTranslational ResearchTreatment EffectivenessUnited States Food and Drug AdministrationVermontVisionWorkYouthaddictionbasebehavioral healthchronic painclinical practicecocaine usecollegecommunity organizationscomorbiditydata privacydesigndigitaldigital healthdigital treatmentdisorder preventionexperienceflexibilityhandheld mobile devicehealth care settingshigh risk populationhigh schoolimplementation scienceimprovedinnovationinsightmarijuana usemedical specialtiesmedication compliancemeetingsmembermobile computingnovelopioid useopioid use disorderpersonalized health carepredictive modelingrandomized trialranpirnaserecruitresearch and developmentresearch studyrural settingscale upscreeningsmart watchsocial mediaspecial interest groupsubstance usesubstance use treatmenttelehealthtreatment disparitywearable sensor technology
项目摘要
Project Summary/Abstract
This proposal is a competing renewal application of the Northeast Node of the National Drug Abuse
Treatment Clinical Trials Network (CTN), which joined the CTN in 2015. The Northeast Node brought
hundreds of community and healthcare partners across the states of New Hampshire, Vermont, and Maine to
the CTN community for the first time. These states have among the very highest rates of substance use in the
U.S., including opioid use, and they include some of the most rural communities in the U.S. The Node has
brought significant expertise to the CTN in conducting practical, rigorous, innovative, and highly impactful trials
focused on improving the treatment of substance use disorders (SUDs) in community systems in the Northeast
and in partnership with other CTN Nodes across the nation. Node Investigators have extensive experience in
leading national and multi-national clinical trials, digital technology; medication and behavioral treatments for
opioid use disorder; co-occurring SUDs and mental health disorders; SUD and chronic pain; SUD in pregnant
women; opioid, cannabis, tobacco, alcohol, stimulant, and polydrug treatment; SUD prevention and treatment
among youth; and implementation science. The Northeast Node is embedded within the Center for Technology
and Behavioral Health (CTBH), a NIDA-funded P30 “Center of Excellence”. The Node thus brings significant
expertise in developing, evaluating, and implementing digital treatments for SUDs, with a focus on overcoming
the striking disparities in treatment access and treatment quality evident in healthcare across the globe.
In the renewal period, the Node proposes to enhance its activities and contributions to the national CTN
to embrace advances in scientific discovery and research innovations that offer great promise for increasing
the reach and effectiveness of treatments for SUDs. The Node will engage a broader group of investigators
that bring additional expertise in data science (bioinformatics, predictive modeling, artificial intelligence, social
media, data privacy/security) and experimental design (micro-randomized trials, adaptive designs, and
implementation/systems science). With this expanded group of partners, it will support and grow a productive
research agenda in the CTN with a focus on (a) digital health and data analytics, including research focused on
providing personalized, science-based resources to individuals with SUD via digital technology and (b)
expanding low threshold access to science-based SUD care, particularly in rural contexts (e.g., general
medical settings; pharmacies; and community organizations). And the Node will lead an expansion of CTN
research on the (c) rapidly evolving landscape of cannabis use as well as (d) co-morbid SUD and mental
health disorders. The Node will establish Community and Policy Advisory Boards to complement the existing
communication infrastructure between Node investigators and their partners, with a focus on identifying the
most significant and timely SUD needs in our communities and scaling-up and sustaining best practices.
项目总结/摘要
这一提案是全国禁毒办东北节点的竞争性续期申请
治疗临床试验网络(CTN),于2015年加入CTN。东北节点带来了
新罕布什尔州、佛蒙特州和缅因州的数百个社区和医疗保健合作伙伴,
CTN社区第一次这些州是美国药物使用率最高的州之一。
美国,包括阿片类药物的使用,他们包括美国一些最农村的社区。
为CTN带来了重要的专业知识,以进行实用,严格,创新和高度影响力的试验
专注于改善东北部社区系统中物质使用障碍(SUD)的治疗
并与全国其他CTN节点合作。节点调查员在以下方面拥有丰富的经验:
领先的国家和跨国临床试验,数字技术;药物和行为治疗,
阿片类药物使用障碍; SUD与精神健康障碍共病; SUD与慢性疼痛;妊娠期SUD
妇女;阿片类药物、大麻、烟草、酒精、兴奋剂和多种药物治疗; SUD预防和治疗
青年;以及实施科学。东北节点嵌入技术中心
和行为健康(CTBH),一个NIDA资助的P30“卓越中心”。因此,节点带来了重大的
开发,评估和实施SUD数字治疗的专业知识,重点是克服
在地球仪的医疗保健中,治疗的可及性和治疗质量存在显著差异。
在更新期间,该节点建议加强其活动,为国家CTN做出贡献
拥抱科学发现和研究创新的进步,为增加
SUD治疗的范围和有效性。该节点将吸引更广泛的调查人员
带来数据科学(生物信息学、预测建模、人工智能、社交
媒体,数据隐私/安全)和实验设计(微随机试验,自适应设计,
执行/系统科学)。有了这个扩大的合作伙伴集团,它将支持和发展一个富有成效的
CTN的研究议程,重点是(a)数字健康和数据分析,包括重点研究
通过数字技术向SUD患者提供个性化的、基于科学的资源,以及(B)
扩大低门槛获得科学的可持续发展保健,特别是在农村地区(例如,一般
医疗机构;药房;和社区组织)。Node将引领CTN的扩张
关于(c)迅速变化的大麻使用情况以及(d)共同发病的SUD和精神疾病的研究
健康失调该节点将建立社区和政策咨询委员会,以补充现有的
Node调查人员及其合作伙伴之间的通信基础设施,重点是确定
最重要和及时的可持续城市发展的需求,在我们的社区和扩大和维持最佳做法。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Lisa A. Marsch其他文献
Barreras de acceso, autoreconocimiento y reconocimiento en depresión y trastornos del consumo del alcohol: un estudio cualitativo
- DOI:
10.1016/j.rcp.2020.11.021 - 发表时间:
2021-06-01 - 期刊:
- 影响因子:
- 作者:
Carlos Gómez-Restrepo;Paula Cárdenas;Arturo Marroquín-Rivera;Magda Cepeda;Fernando Suárez-Obando;José Miguel Uribe-Restrepo;Sergio Castro;Leonardo Cubillos;William C. Torrey;Sophia M. Bartels;Catherine Van Arcken-Martínez;Sena Park;Deepak John;Lisa A. Marsch - 通讯作者:
Lisa A. Marsch
Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? Early experiences in the feasibility study phase of a National Drug Abuse Treatment Clinical Trials Network Trial
- DOI:
10.1186/s13722-021-00233-x - 发表时间:
2021-04-20 - 期刊:
- 影响因子:3.200
- 作者:
Yih-Ing Hser;Allison J. Ober;Alex R. Dopp;Chunqing Lin;Katie P. Osterhage;Sarah E. Clingan;Larissa J. Mooney;Megan E. Curtis;Lisa A. Marsch;Bethany McLeman;Emily Hichborn;Laurie S. Lester;Laura-Mae Baldwin;Yanping Liu;Petra Jacobs;Andrew J. Saxon - 通讯作者:
Andrew J. Saxon
Relación entre las características sociodemográficas de los participantes del proyecto DIADA y la tasa de cumplimiento al seguimiento en la fase inicial de la intervención
- DOI:
10.1016/j.rcp.2020.11.019 - 发表时间:
2021-06-01 - 期刊:
- 影响因子:
- 作者:
María Paula Cárdenas Charry;Maria Paula Jassir Acosta;José Miguel Uribe Restrepo;Magda Cepeda;Pablo Martínez Camblor;Leonardo Cubillos;Sophia M. Bartels;Sergio Castro;Lisa A. Marsch;Carlos Gómez-Restrepo - 通讯作者:
Carlos Gómez-Restrepo
Comparative efficacy of a computer-based HIV testing video intervention in sites of varying HIV prevalence
- DOI:
10.1016/j.drugalcdep.2014.09.040 - 发表时间:
2015-01-01 - 期刊:
- 影响因子:
- 作者:
Ian D. Aronson;Sonali Rajan;Lisa A. Marsch;Juline Koken;Theodore Bania - 通讯作者:
Theodore Bania
Caracterización de los usuarios de las redes sociales dentro del sistema de atención primaria en Colombia y predictores de su uso de las redes sociales para comprender su salud
- DOI:
10.1016/j.rcp.2020.12.010 - 发表时间:
2021-06-01 - 期刊:
- 影响因子:
- 作者:
Sophia M. Bartels;Pablo Martinez-Camblor;John A. Naslund;Fernando Suárez-Obando;William C. Torrey;Leonardo Cubillos;Makeda J. Williams;Sergio M. Castro;José M. Uribe-Restrepo;Carlos Gómez-Restrepo;Lisa A. Marsch - 通讯作者:
Lisa A. Marsch
Lisa A. Marsch的其他文献
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{{ truncateString('Lisa A. Marsch', 18)}}的其他基金
Technology-based Treatments for Substance Use Disorders
基于技术的药物使用障碍治疗
- 批准号:
10268734 - 财政年份:2021
- 资助金额:
$ 25.48万 - 项目类别:
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