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Novel Candidate Genes, Lung Function and Allergic Airways Disease

Novel Candidate Genes, Lung Function and Allergic Airways Disease
新候选基因、肺功能和过敏性气道疾病
批准号:
nhmrc : 546428
负责人:
A/Pr Chrishan Samuel
金额:
$38.8万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31

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中文摘要
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英文摘要
We propose to study airway remodelling (structural changes to the airway) and in asthma using human samples and rodent models of asthma. We are particularly interested in investigating the role of trefoil peptide 2 and relaxin, two genes identified as determining lung function. To do this we need to understand the mechanisms of airway remodelling and its impact on disease severity in the patient. A strength of this study is availability of samples from a large study of human asthma.
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Pharmacological inhibition of IRAP as a novel antifibrotic strategy
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  • 项目类别:
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  • 财政年份:
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  • 依托单位:
Pharmacological inhibition of IRAP as a novel antifibrotic strategy
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Unraveling fibrosis by pharmacological targeting of the G protein-coupled receptor, RXFP1
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  • 项目类别:
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Unraveling fibrosis by pharmacological targeting of the G protein-coupled receptor, RXFP1
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    nhmrc : 1122170
  • 项目类别:
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  • 资助金额:
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  • 负责人:
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  • 依托单位:
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