Novel Candidate Genes, Lung Function and Allergic Airways Disease
Novel Candidate Genes, Lung Function and Allergic Airways Disease
批准号:
nhmrc : 546428
负责人:
A/Pr Chrishan Samuel
金额:
$38.8万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
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英文摘要
We propose to study airway remodelling (structural changes to the airway) and in asthma using human samples and rodent models of asthma. We are particularly interested in investigating the role of trefoil peptide 2 and relaxin, two genes identified as determining lung function. To do this we need to understand the mechanisms of airway remodelling and its impact on disease severity in the patient. A strength of this study is availability of samples from a large study of human asthma.
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Pharmacological inhibition of IRAP as a novel antifibrotic strategy
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批准号:nhmrc : GNT1146049
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项目类别:Project Grants
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资助金额:$103.64万
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财政年份:2018
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负责人:A/Pr Chrishan Samuel
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依托单位:
Pharmacological inhibition of IRAP as a novel antifibrotic strategy
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批准号:nhmrc : 1146049
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项目类别:Project Grants
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资助金额:$70.07万
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财政年份:2018
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负责人:A/Pr Chrishan Samuel
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依托单位:
Unraveling fibrosis by pharmacological targeting of the G protein-coupled receptor, RXFP1
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批准号:nhmrc : GNT1122170
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项目类别:Project Grants
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资助金额:$79.86万
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财政年份:2017
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负责人:A/Pr Chrishan Samuel
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依托单位:
Unraveling fibrosis by pharmacological targeting of the G protein-coupled receptor, RXFP1
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批准号:nhmrc : 1122170
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项目类别:Project Grants
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资助金额:$54.45万
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财政年份:2017
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负责人:A/Pr Chrishan Samuel
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依托单位:
Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.
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批准号:nhmrc : GNT1101552
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项目类别:Project Grants
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资助金额:$104.93万
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财政年份:2016
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负责人:A/Pr Chrishan Samuel
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依托单位:
Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.
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批准号:nhmrc : 1101552
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项目类别:Project Grants
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资助金额:$72.15万
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财政年份:2016
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负责人:A/Pr Chrishan Samuel
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依托单位:
Tubulointerstitial Epigenetics- The Underlying Basis of Progressive Fibrosis in Kidney Disease
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批准号:nhmrc : 1078694
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项目类别:Project Grants
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资助金额:$25.27万
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财政年份:2015
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负责人:A/Pr Chrishan Samuel
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依托单位:
Tubulointerstitial Epigenetics- The Underlying Basis of Progressive Fibrosis in Kidney Disease
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批准号:nhmrc : GNT1078694
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项目类别:Project Grants
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资助金额:$36.71万
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财政年份:2015
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负责人:A/Pr Chrishan Samuel
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依托单位:
Developing Relaxin Peptides as Novel Therapies for Fibrosis
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批准号:nhmrc : 1041766
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项目类别:Research Fellowships
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资助金额:$50.1万
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财政年份:2013
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负责人:A/Pr Chrishan Samuel
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依托单位:
Developing Novel Therapies for Fibrosis
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批准号:nhmrc : GNT1041766
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项目类别:Research Fellowships
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资助金额:$59.08万
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财政年份:2013
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负责人:A/Pr Chrishan Samuel
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依托单位:
Relaxin therapy reverses large artery remodelling and stiffening in aged and hypertensive models
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批准号:nhmrc : 1004235
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项目类别:Project Grants
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资助金额:$29.67万
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财政年份:2011
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负责人:A/Pr Chrishan Samuel
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依托单位:
Molecular mechanisms of renal fibrosis
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批准号:nhmrc : 628634
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项目类别:NHMRC Project Grants
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资助金额:$25.0万
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财政年份:2010
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负责人:A/Pr Chrishan Samuel
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依托单位:
Investigating the anti-fibrotic properties of relaxin in the normal and diseased heart
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批准号:nhmrc : 454636
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项目类别:Career Development Fellowships
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资助金额:$31.95万
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财政年份:2007
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负责人:A/Pr Chrishan Samuel
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依托单位:
海外基金