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Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.

Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.
了解 AT2R 对女性的心脏保护作用:通过松弛素在 AT1 和 AT2 受体功能平衡之间切换。
批准号:
nhmrc : 1101552
负责人:
A/Pr Chrishan Samuel
金额:
$72.15万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2019-12-31

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中文摘要
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英文摘要
Women are protected from cardiovascular disease as compared to age-matched men, an effect lost with age. Understanding protective factors that act in females could be used to treat hypertension, heart failure and stroke in males at all ages, and maintain protection in elderly women. Our studies aim to determine if relaxin, an ovarian hormone, can promote cardiovascular health in women.
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