Core A: Administrative Core

核心A：行政核心

• 批准号: 10588795
• 负责人: Carol Fuzeti Elias
• 金额: $ 16.15万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-01 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10588795
• 关键词: Administrator; Advertisements; Advisory Committees; Animals; Biotechnology; Budgets; Charge; Communication; Complex; Contracts; Counseling; Data; Data Analyses; Databases; Development; Diabetes Mellitus; Ensure; Equipment; Fee-for-Service Plans; Feedback; Funding; Germ-Free; Guidelines; Income; Institution; Laboratories; Leadership; Metabolic; Michigan; Modeling; Monitor; Mus; National Institute of Diabetes and Digestive and Kidney Diseases; Obesity; Phenotype; Physiological; Preparation; Principal Investigator; Procedures; Progress Reports; Protocols documentation; Quality Control; Records; Recovery; Reporting; Research; Research Personnel; Resources; Schedule; Secure; Services; Standardization; Technology; Training; Universities; Work; animal care; behavioral phenotyping; cost; data submission; experience; meetings; metabolic phenotype; nutrition; programs; synergism; web site

Abstract/Summary – Administrative Core The Administrative Core will be responsible for the overall leadership and scientific oversight of the Michigan Metabolic Phenotyping of live Models of Obesity and Diabetes (Mi-MPMOD) Center. The Core will provide administrative assistance to the Animal Care and Germ-Free Core and the Metabolic, Physiological and Behavioral (MPB) Phenotyping Core and ensure that their services are delivered efficiently and to the highest possible standards. The leadership team has extensive administrative experience and is centrally located in the North Campus Research Complex at the Elizabeth W. Caswell Diabetes Institute (CDI), adjacent to administrative cores of the Michigan Diabetes Research Center (MDRC), the Michigan Nutrition and Obesity Research Center (MNORC) and the CDI. This clustering of related Administrative Cores facilitates an efficient use of space and equipment and leverages the collective experience of all centers’ administrators assuring the transfer of best practices among them. The administrative core will: a) Coordinate the receipt of animals and assignments for the appropriate phenotyping services; b) monitor studies progress until completion of data analysis and submission of final reports to the requesting investigator(s); c) ensure secure processing and signing of all necessary conditions of use statements, contracts, service fees, and data records as well as the subsequent data submission to the MPMOD Consortium and Coordinating Unit (CU) database; d) manage budgetary and workflow records, oversee cost recovery, program income and adjustment of service charges; e) re-budget Center funds based on the cores service activity and scientific needs; f) promote the availability of MPMOD resources to local investigators, regional partners, and nationwide research institutions, including academic and for-profit biotechnology and pharma companies; g) develop communication strategies to specifically target underrepresented PIs and small laboratories or institutions that have not received significant federal research funding through advertisement, seminars, and direct contact with the academic departments; h) facilitate the development of new research technology and training resources for the Center’s MPB Phenotyping Core; and i) meet regularly with the Advisory committees and oversee the preparation and submission of annual progress report to NIDDK. The Administrative Core will work closely with the Centers’ Consortium and the national CU by actively participating in the solicitation and review of applications for the MPMOD Consortium’s funding programs. It will also work in synergy with the Consortium and CU to minimize overlap of services and establish, standardize, document, and distribute phenotyping protocols and quality control procedures to laboratories nationwide.

摘要/摘要 - 行政核心 行政核心将负责密歇根州的整体领导和科学监督 肥胖和糖尿病现场模型（MI-MPMOD）中心的代谢表型。核心将提供 对动物护理和无菌核心以及代谢，生理和 行为（MPB）表型核心，并确保其服务有效地交付，并达到最高 可能的标准。领导团队拥有丰富的行政经验，位于中央 伊丽莎白·W·卡斯韦尔糖尿病研究所（CDI）的北校园研究综合体 密歇根州糖尿病研究中心（MDRC）的行政核心，密歇根州的营养和肥胖症 研究中心（MNORC）和CDI。相关行政核心设施的这种聚类有效 使用太空和设备，并利用所有中心管理员的集体经验 其中最佳实践的转移。行政核心将：a）协调动物的接收和 适当的表型服务的作业； b）监测研究进展直到完成数据 分析和提交最终报告给请求的调查员； c）确保安全处理和 签署所有必要条件的使用声明，合同，服务费和数据记录以及 随后的数据提交到MPMOD联盟和协调单元（CU）数据库； d）管理 预算和工作流记录，海外成本回收，计划收入和服务费用调整； e）基于核心服务活动和科学需求的重新预算中心资金； f）促进可用性 MPMOD资源向当地调查人员，区域合作伙伴和全国研究机构，包括 学术和营利性生物技术和制药公司； g）发展沟通策略 特别针对尚未收到大量大量的PIS和小型实验室或机构的目标 联邦研究通过广告，半货形和与学术部门的直接联系； h）促进该中心MPB的新研究技术和培训资源的开发 表型核心；我）定期与咨询委员会会面，并监督准备工作 提交给NIDDK的年度进度报告。行政核心将与中心紧密合作 财团和国家铜通过积极参与申请和审查的申请 MPMOD财团的资金计划。它也将与财团和CU协同作用，以最大程度地减少 服务和机构重叠，标准化，记录和分发表型协议和质量 全国实验室的控制程序。