Core A: Administrative Core

摘要/摘要-行政核心 行政核心将负责密歇根大学的整体领导和科学监督。 肥胖和糖尿病活体模型的代谢表型（Mi-MPMOD）中心。核心将提供 动物护理和无菌核心和代谢，生理和 行为（MPB）表型核心，并确保他们的服务是高效和最高的交付 可能的标准。领导团队拥有丰富的行政经验， 北校区研究综合体在伊丽莎白W。Caswell糖尿病研究所（CDI），毗邻 密歇根糖尿病研究中心（MDRC），密歇根营养和肥胖 研究中心（MNORC）和CDI。相关管理核心的这种集群有助于高效地 利用空间和设备，并利用所有中心管理人员的集体经验， 在它们之间交流最佳做法。行政核心将：a）协调动物的接收， 分配适当的表型分析服务; B）监测研究进展，直至完成数据 分析并向提出请求的研究者提交最终报告; c）确保安全处理， 签署所有必要的使用条件声明、合同、服务费和数据记录，以及 随后向MPMOD联合体和协调单位（CU）数据库提交数据; d）管理 预算和工作流程记录，监督成本回收，计划收入和调整服务收费; e）根据核心服务活动和科学需求重新预算中心资金; f）促进 向当地研究者、区域合作伙伴和全国性研究机构提供MPMOD资源，包括 学术和营利性生物技术和制药公司; g）制定沟通战略， 专门针对代表性不足的PI和小型实验室或机构， 联邦研究基金通过广告，研讨会，并与学术部门的直接联系; h）为中心的MPB开发新的研究技术和培训资源提供便利 表型核心;以及i）定期与咨询委员会会面，并监督准备工作， 向NIDDK提交年度进度报告。行政核心将与各中心的 联合会和国家CU通过积极参与征集和审查申请， MPMOD财团的资助计划。该公司亦会与联合会和CU合作，尽量减少 重叠的服务和建立，标准化，文件化，并分发表型方案和质量 全国实验室的控制程序。

Abstract/Summary – Administrative Core The Administrative Core will be responsible for the overall leadership and scientific oversight of the Michigan Metabolic Phenotyping of live Models of Obesity and Diabetes (Mi-MPMOD) Center. The Core will provide administrative assistance to the Animal Care and Germ-Free Core and the Metabolic, Physiological and Behavioral (MPB) Phenotyping Core and ensure that their services are delivered efficiently and to the highest possible standards. The leadership team has extensive administrative experience and is centrally located in the North Campus Research Complex at the Elizabeth W. Caswell Diabetes Institute (CDI), adjacent to administrative cores of the Michigan Diabetes Research Center (MDRC), the Michigan Nutrition and Obesity Research Center (MNORC) and the CDI. This clustering of related Administrative Cores facilitates an efficient use of space and equipment and leverages the collective experience of all centers’ administrators assuring the transfer of best practices among them. The administrative core will: a) Coordinate the receipt of animals and assignments for the appropriate phenotyping services; b) monitor studies progress until completion of data analysis and submission of final reports to the requesting investigator(s); c) ensure secure processing and signing of all necessary conditions of use statements, contracts, service fees, and data records as well as the subsequent data submission to the MPMOD Consortium and Coordinating Unit (CU) database; d) manage budgetary and workflow records, oversee cost recovery, program income and adjustment of service charges; e) re-budget Center funds based on the cores service activity and scientific needs; f) promote the availability of MPMOD resources to local investigators, regional partners, and nationwide research institutions, including academic and for-profit biotechnology and pharma companies; g) develop communication strategies to specifically target underrepresented PIs and small laboratories or institutions that have not received significant federal research funding through advertisement, seminars, and direct contact with the academic departments; h) facilitate the development of new research technology and training resources for the Center’s MPB Phenotyping Core; and i) meet regularly with the Advisory committees and oversee the preparation and submission of annual progress report to NIDDK. The Administrative Core will work closely with the Centers’ Consortium and the national CU by actively participating in the solicitation and review of applications for the MPMOD Consortium’s funding programs. It will also work in synergy with the Consortium and CU to minimize overlap of services and establish, standardize, document, and distribute phenotyping protocols and quality control procedures to laboratories nationwide.