Assessing the Impact of Cannabis Legalization on Adolescent Cannabis Use and Cannabis-Related Health Conditions
评估大麻合法化对青少年大麻使用和大麻相关健康状况的影响
基本信息
- 批准号:10588148
- 负责人:
- 金额:$ 69.01万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-05-01 至 2027-02-28
- 项目状态:未结题
- 来源:
- 关键词:Accident and Emergency departmentAccidentsAcuteAddressAdolescenceAdolescentAdvertisingAmericanAnxietyAreaBrainCaliforniaCannabinoidsCannabisCannabis policyClinicalCommunitiesComplementDataDecision AidDecision MakingDevelopmentDiagnosisEducationElectronic Health RecordEmergency Department PhysicianEmergency department visitEventFocus GroupsFutureGeographic Information SystemsHealthHealth PersonnelHealth PolicyHealthcareHeterogeneityHomeIndividualIntegrated Delivery of Health CareIntegrated Health Care SystemsInterruptionInterventionInterviewIntoxicationKnowledgeLawsLegalLocal GovernmentLocationLow incomeMapsMarijuana DependenceMarketingMedical MarijuanaMedicineMental DepressionMental HealthMethodsNational Institute of Drug AbuseNatural experimentParentsPatientsPerceptionPoisoningPoliciesPopulation HeterogeneityProviderPsychosesPublic HealthPublic Health PracticeQuasi-experimentRecreationReportingResearchRespiratory DiseaseRespiratory Signs and SymptomsRiskRisk FactorsSamplingSchemeSchizophreniaSeriesShapesStudy modelsSubgroupSuicideSyndromeSystemTaxesTeenagersTestingTimeUS StateVehicle crashWithdrawalYouthaddictioncigarette smokingclinical careclinical practicecontextual factorsdesigndisorder riskepidemiology studyhealth service usehealth warninghigh riskillicit drug useinnovationinsightmarijuana legalizationmarijuana usemarijuana use disordermeetingsmotor vehicle injurypediatric departmentpediatricianpsychiatric comorbiditypublic health prioritiespublic health relevancerespiratoryscreeningstandard caresubstance usetrend
项目摘要
PROJECT SUMMARY/ABSTRACT
Adolescent cannabis use is increasingly recognized as an important public health problem with significant
adverse health consequences. Recreational cannabis legalization (RCL) has high potential to increase risk for
adolescent cannabis use and cannabis-related health conditions. However, the effects of RCL on adolescents
are unknown. With a highly representative sample of nearly 1 million adolescents (N=900,000) regularly
screened for cannabis use in Kaiser Permanente Northern California’s large integrated healthcare delivery
system from 2015 to 2023, this multi-method study will address the pressing public health questions of whether
and how California state RCL and heterogeneity of local regulatory schemes impact the risk of adolescent
cannabis use and cannabis-related health conditions. We will use a quasi-experimental interrupted time series
design to test whether adolescent cannabis use, cannabis-related health conditions (e.g., cannabis use
disorder, other substance use, respiratory symptoms, mental health problems, cannabis-related accidents,
acute cannabis intoxication, cannabinoid hyperemesis syndrome), and cannabis-related healthcare use (e.g.,
emergency department, addiction treatment) and rise post-RCL. We will also examine local RCL policies
(retailer bans or caps, product and advertising restrictions, taxes, health warnings) and use geographic
information systems methods to map retailer location (e.g., distance from home address to the closest retailer)
onto individual-level electronic health record data collected in clinical care to test whether the effects of RCL
are stronger among those who live in communities with less restrictive local policies, adjusting for pre-RCL
medical cannabis policies. We will conduct hypothesis-driven moderation analyses to identify sub-groups
whose risk for cannabis use and cannabis-related health conditions may be greatest following RCL. To gain
further clinical insight into our quantitative data and guide next steps, we will conduct focus groups with
adolescents and interviews with addiction medicine clinicians, pediatricians, and emergency department
physicians to gain insight into how RCL impacts adolescent cannabis use and addiction treatment need from
the perspective of both patients and providers. Together, results will have immediate public health and clinical
implications, providing urgently needed data to identify potentially actionable areas for future policy adaptations
and aid decision making for public health practices to reduce adolescent cannabis use and cannabis-related
harms.
项目概要/摘要
青少年吸食大麻越来越被认为是一个重要的公共卫生问题,具有重大影响
不良的健康后果。娱乐性大麻合法化(RCL)极有可能增加大麻风险
青少年大麻使用和与大麻相关的健康状况。然而,RCL 对青少年的影响
未知。定期抽取近 100 万青少年 (N=900,000) 的高度代表性样本
在 Kaiser Permanente 北加州大型综合医疗保健服务中筛查大麻使用情况
系统从 2015 年到 2023 年,这项多方法研究将解决紧迫的公共卫生问题:
以及加利福尼亚州 RCL 和地方监管计划的异质性如何影响青少年的风险
大麻使用和与大麻相关的健康状况。我们将使用准实验中断时间序列
旨在测试青少年是否使用大麻、与大麻相关的健康状况(例如,使用大麻
疾病、其他物质使用、呼吸道症状、心理健康问题、大麻相关事故、
急性大麻中毒、大麻素剧吐综合征)以及与大麻相关的医疗保健用途(例如,
急诊室、成瘾治疗)并在 RCL 后升职。我们还将研究当地的 RCL 政策
(零售商禁令或上限、产品和广告限制、税收、健康警告)并使用地理信息
绘制零售商位置地图的信息系统方法(例如,从家庭住址到最近零售商的距离)
分析在临床护理中收集的个人电子健康记录数据,以测试 RCL 是否有影响
根据 RCL 前的情况进行调整,居住在当地政策限制较少的社区的人们的影响力更强
医用大麻政策。我们将进行假设驱动的调节分析来识别子组
RCL 后,其使用大麻和大麻相关健康状况的风险可能最大。为了获得
为了进一步了解我们的定量数据并指导后续步骤,我们将开展焦点小组讨论
青少年以及对成瘾医学临床医生、儿科医生和急诊科的采访
医生可以深入了解 RCL 如何影响青少年大麻使用和成瘾治疗需求
患者和提供者的观点。总之,结果将立即影响公共卫生和临床
影响,提供迫切需要的数据,以确定未来政策调整的潜在可行领域
并协助公共卫生实践决策,以减少青少年大麻使用和大麻相关问题
危害。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kelly Corinne Young-Wolff其他文献
Kelly Corinne Young-Wolff的其他文献
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{{ truncateString('Kelly Corinne Young-Wolff', 18)}}的其他基金
Modes of Cannabis Administration and Polysubstance Use among Women Before and During Pregnancy
妇女怀孕前和怀孕期间的大麻管理和多物质使用模式
- 批准号:
10801994 - 财政年份:2023
- 资助金额:
$ 69.01万 - 项目类别:
Assessing the Impact of Cannabis Legalization on Adolescent Cannabis Use and Cannabis-Related Health Conditions
评估大麻合法化对青少年大麻使用和大麻相关健康状况的影响
- 批准号:
10367873 - 财政年份:2022
- 资助金额:
$ 69.01万 - 项目类别:
Identifying Risk Factors for Prenatal Substance and Polysubstance Use
识别产前药物和多种药物使用的风险因素
- 批准号:
9891038 - 财政年份:2017
- 资助金额:
$ 69.01万 - 项目类别:
Interaction of Genes, Stress, and Cognitions in the Development of Alcoholism
酗酒发展过程中基因、压力和认知的相互作用
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8120994 - 财政年份:2009
- 资助金额:
$ 69.01万 - 项目类别:
Interaction of Genes, Stress, and Cognitions in the Development of Alcoholism
酗酒发展过程中基因、压力和认知的相互作用
- 批准号:
7753051 - 财政年份:2009
- 资助金额:
$ 69.01万 - 项目类别:
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