Administrative Supplement to Physical Activity, Sedentary Behavior, and Venous Thromboembolism Risk
对体力活动、久坐行为和静脉血栓栓塞风险的行政补充
基本信息
- 批准号:10273740
- 负责人:
- 金额:$ 5.34万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-08-19 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:AccelerometerAdministrative SupplementAgingAreaBiological MarkersBlood coagulationCardiac rehabilitationCardiovascular DiseasesCardiovascular systemClinicalComplexCross-Over StudiesDataData CollectionDeep Vein ThrombosisDoctor of PhilosophyElderlyEpidemiologistEpidemiologyEvaluationEventFemaleFibrin fragment DFundingFutureGenerationsGoalsGuidelinesHemostatic AgentsHemostatic functionHourIncidenceIndividualK-Series Research Career ProgramsLifeLife StyleMalignant NeoplasmsMeasuresMentored Research Scientist Development AwardMentorsMethodologyMorbidity - disease rateNational Heart, Lung, and Blood InstituteNested Case-Control StudyNurses&apos Health StudyObesityOutcomeParentsPatient Self-ReportPersonsPhysical activityPopulationPrognosisPublic HealthPublishingPulmonary EmbolismRecommendationReportingResearchResearch DesignRiskRisk FactorsScientistSecondary PreventionStrenuous ExerciseSurvivorsThrombinTrainingTriad Acrylic ResinUnited StatesUnited States National Institutes of HealthVenousWomanWomen&aposs HealthWorkactivated Protein Cadverse outcomebasecardiovascular risk factorcareercareer developmentcohortdesignepidemiology studyimprovedinnovationmalemoderate-to-vigorous physical activitymodifiable riskmortalitypublic health relevancesedentary lifestylethromboticvenous thromboembolism
项目摘要
Summary
Venous thromboembolism (VTE) is the third most common cardiovascular disease in the United States.
Venous stasis, which can occur during prolonged periods of inactivity, is a known risk factor for VTE; however,
the relationship between physical activity and VTE is inconsistent and guidance regarding physical activity after
a VTE is lacking. The overarching goal of this proposed “Administrative Supplement for Continuity and
Retention of NIH Mentored Career Development (K) Award Recipients and Scholars” is to provide
supplemental support of the scientific and training aims of the NHLBI-funded K01, “Physical Activity, Sedentary
Behavior, and Venous Thromboembolism Risk”, following a life event. Dr. Laura B. Harrington's ongoing parent
K01 award aims to further our understanding of physical activity and sedentary behavior in relation to: (1)
incident VTE risk, (2) short-term VTE risk following physical activity, (3) long-term prognosis following an
incident VTE, and (4) hemostatic factor levels, which are associated with thrombotic event risk. This study
leverages existing data from the Women's Health Initiative and the Nurses' Health Studies I and II cohorts in
addition to newly collecting data in the setting of a case-crossover study. Innovative aspects of the proposed
work include the evaluation of accelerometer-measured physical activity and sedentary behavior in relation to
VTE risk, the evaluation of VTE risk following physical activity using case-crossover methodology, the
evaluation of physical activity and sedentary behavior with long-term prognosis among VTE survivors, and the
evaluation of usual physical activity in relation to hemostatic parameter measures. Not only are the proposed
scientific aims of
总结
静脉血栓栓塞(VTE)是美国第三大常见的心血管疾病。
静脉淤滞,可能发生在长期不活动期间,是VTE的已知风险因素;然而,
体力活动和VTE之间的关系是不一致的,
缺乏职业教育。这一拟议的“连续性和
保留NIH指导职业发展(K)奖获得者和学者”是为了提供
补充支持NHLBI资助的K 01“体育活动,久坐不动”的科学和培训目标
行为和静脉血栓栓塞风险”。劳拉B医生。哈灵顿的现任家长
K 01奖旨在进一步了解身体活动和久坐行为与以下方面的关系:(1)
偶发性VTE风险,(2)体力活动后的短期VTE风险,(3)
偶发性VTE和(4)止血因子水平,与血栓形成事件风险相关。本研究
利用妇女健康倡议和护士健康研究I和II队列的现有数据,
除了在病例交叉研究中新收集的数据外。拟议战略的创新方面
工作包括评估加速度计测量的身体活动和久坐不动的行为,
VTE风险,使用病例交叉方法评价体力活动后的VTE风险,
评估VTE幸存者的体力活动和久坐行为与长期预后,
评价与止血参数测量相关的日常体力活动。不仅提议
科学目的
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Laura Brienne Harrington其他文献
Laura Brienne Harrington的其他文献
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{{ truncateString('Laura Brienne Harrington', 18)}}的其他基金
Venous Thromboembolism Sequelae in a Population-based Inception Cohort
基于人群的初始队列中的静脉血栓栓塞后遗症
- 批准号:
10556744 - 财政年份:2023
- 资助金额:
$ 5.34万 - 项目类别:
Physical Activity, Sedentary Behavior, and Venous Thromboembolism Risk
体力活动、久坐行为和静脉血栓栓塞风险
- 批准号:
9975213 - 财政年份:2018
- 资助金额:
$ 5.34万 - 项目类别:
Physical Activity, Sedentary Behavior, and Venous Thromboembolism Risk
体力活动、久坐行为和静脉血栓栓塞风险
- 批准号:
10202701 - 财政年份:2018
- 资助金额:
$ 5.34万 - 项目类别:
Physical Activity, Sedentary Behavior, and Venous Thromboembolism Risk
体力活动、久坐行为和静脉血栓栓塞风险
- 批准号:
9766351 - 财政年份:2018
- 资助金额:
$ 5.34万 - 项目类别:
Physical Activity, Sedentary Behavior, and Venous Thromboembolism Risk
体力活动、久坐行为和静脉血栓栓塞风险
- 批准号:
9598236 - 财政年份:2018
- 资助金额:
$ 5.34万 - 项目类别:
Physical Activity, Sedentary Behavior, and Venous Thromboembolism Risk
体力活动、久坐行为和静脉血栓栓塞风险
- 批准号:
10461777 - 财政年份:2018
- 资助金额:
$ 5.34万 - 项目类别:
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