通过重复经颅磁刺激治疗兴奋剂成瘾-猫眼课题宝

通过重复经颅磁刺激治疗兴奋剂成瘾

批准号：

10237180

负责人：

JONG H YOON

金额：

$0.0万

依托单位：

VETERANS ADMIN PALO ALTO HEALTH CARE SYS

依托单位国家：

美国

项目类别：

财政年份：

2020

资助国家：

美国

项目状态：

已结题

起止时间：

2020-09-01 至 2023-04-30

来源：

https://reporter.nih.gov/project-details/10237180

关键词：

Abstinence Adaptive Behaviors Affective Aftercare Amphetamines Behavioral Biological Markers Brain Brain region Clinical Cocaine Cognitive Controlled Study Data Development Disease Dopamine Double-Blind Method FDA approved Feasibility Studies Frequencies Functional Magnetic Resonance Imaging Functional disorder Health Homelessness Intervention Left Legal Major Depressive Disorder Measures Methods Morbidity - disease rate Occupational Participant Patient Selection Personal Satisfaction Pharmaceutical Preparations Placebos Prediction of Response to Therapy Prefrontal Cortex Process Property Psychopathology Psychostimulant dependence Randomized Refractory Relapse Research Design Rewards Role Services Signal Transduction Suicide Toxicology Urine Veterans adaptive learning addiction base cost effective design disability drug of abuse functional MRI scan functional status improved magnetic field methamphetamine use neuropsychiatry psychosocial randomized controlled study relapse prediction relating to nervous system repetitive transcranial magnetic stimulation reward processing sham-controlled study social deficits stimulant use stimulant use disorder treatment comparison treatment group

项目摘要

项目成果

JONG H YOON的其他基金

相似基金

相关文献

中文摘要

翻译

点击翻译按钮获取中文摘要

英文摘要

Stimulant use disorder accounts for significant disability and dysfunction among Veterans. We currently do not have effective somatic treatments for this condition. This proposal will conduct a feasibility study to determine our ability to administer and complete a double-blind, sham-controlled randomized study using repetitive transcranial stimulation (rTMS) for treating stimulant use disorder. Half of the participants will be randomly assigned to receive sham treatment and the other half to receive active rTMS to the dorsolateral prefrontal cortex (DLPFC). We will also obtain pilot data supporting the efficacy of rTMS on reducing relapse rates and improving psychosocial functioning. And lastly, we will complete an exploratory aim in which we will obtain pilot data on the ability of fMRI scans to yield biomarkers that will be useful in selecting which Veterans would most benefit from intensive interventions such as rTMS

期刊论文(0)

专著(0)

科研奖励(0)

会议论文