Core A: Administrative Core

核心A：行政核心

• 批准号: 10264623
• 负责人: RUSSELL H. SWERDLOW
• 金额: $ 50.57万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10264623
• 关键词: Address; Advisory Committees; Advocate; Alzheimer' s Disease; Alzheimer' s disease related dementia; Area; Automobile Driving; Budgets; Clinical; Clinical Trials; Consent; Consultations; Data; Development; Education; Ensure; Faculty; Fund Raising; Funding; Genomics; Goals; Government; Grant; Growth; Infrastructure; Intervention Studies; Kansas; Metabolism; Mitochondria; Molecular; Monitor; Patient Care; Pilot Projects; Play; Prevention Research; Prevention strategy; Productivity; Program Development; Progress Reports; Public Relations; Research; Research Personnel; Resources; Role; Services; Site Visit; Strategic Planning; United States National Institutes of Health; Universities; Visit; Work; aging brain; base; design; effective therapy; empowered; falls; lifestyle intervention; meetings; mitochondrial metabolism; neuroimaging; operation; programs; ranpirnase; recruit; success; symposium; treatment strategy

ABSTRACT: ADMINISTRATIVE CORE The Administrative Core oversees operational and strategic planning for the University of Kansas Alzheimer's Disease Research Center (KU ADRC). Over a decade of P30 support, the Core managed growth that saw us become a leader in AD mitochondria/metabolism, lifestyle intervention, and prevention research. Supporting these programs required us to develop and implement unique infrastructure that promotes specialized molecular, clinical trial, recruitment, education, and patient care initiatives. In addition to defining Center strategy, the Core manages the resources needed to support our investigators. This includes biospecimen procurement plans; consent and compliance requirements; ensuring biospecimen storage; and facilitating access to biospecimens, data, consultation, and other Center services. We advise our other cores, monitor their productivity, and promote their seamless and synergistic cooperation. We verify NIA programmatic obligations are efficiently met and maintain Internal and External Advisory Committees. Up to this point we ran an immensely successful pilot project program; from 2011 through 2019 we saw 27 of 40 (68%) of our pilot recipients receive external grant support. The Core ensures all KU ADRC components receive adequate financial resources. Beyond managing our P30 budget, we accomplish this by identifying and procuring dollars from institutional ADRC stakeholders, developing philanthropy, and submitting P30 supplements. Whether designing strategy, tracking down dollars, identifying space, building resources, developing investigators, or growing the Center and advancing its agenda, the Administrative Core plays an integral role in both short-and-long term KU ADRC successes. Over the past 10 years we clearly transformed AD, AD-related, and brain aging research at the University of Kansas. During our next cycle we will continue our trajectory of guided, strategic growth that advances the AD research field and moves us closer to effective treatments and prevention strategies. We will accomplish these goals by focusing on a defined set of specific aims that include: (1) Managing infrastructure and routine operations; (2) Developing and empowering intellectual assets; and (3) Defining goals and amplifying impact.

摘要：管理核心 行政核心负责堪萨斯大学的运营和战略规划 阿尔茨海默氏病研究中心（KU ADRC）。多十年的P30支持，核心管理的增长 这使我们成为AD线粒体/代谢，生活方式干预和预防研究的领导者。 支持这些计划需要我们开发和实施促进的独特基础架构 专门的分子，临床试验，招聘，教育和患者护理计划。 除了定义中心战略外，核心还管理支持我们的资源 调查人员。这包括生物测量采购计划；同意和合规要求；确保 生物测量存储；并促进获得生物测量，数据，咨询和其他中心服务的访问。 我们建议我们的其他核心，监控其生产力，并促进他们的无缝和协同合作。 我们验证了NIA的编程义务，并维护内部和外部咨询 委员会。到目前为止，我们开展了一项成功的试点项目计划；从2011年到2019年 我们看到40名（68％）的飞行员收件人获得了外部赠款支持。核心确保所有KU ADRC 组件获得足够的财务资源。除了管理P30预算外，我们还通过 从机构ADRC利益相关者那里识别和采购美元，发展慈善事业并提交 P30补充剂。 是否设计策略，追踪美元，识别空间，建设资源，开发 调查人员或发展中心并推进其议程，行政核心在 两个短期的KU ADRC术语取得了成功。在过去的十年中，我们清楚地改变了广告，广告相关， 和堪萨斯大学的大脑老化研究。在下一个周期中，我们将继续我们的轨迹 指导，战略增长，发展了广告研究领域，并使我们更接近有效的治疗和 预防策略。我们将通过关注一组定义的特定目标来实现这些目标 包括：（1）管理基础架构和常规操作； （2）发展和授权智力 资产; （3）定义目标并放大影响。