Core A: Administrative Core

核心A：行政核心

• 批准号: 10264623
• 负责人: RUSSELL H. SWERDLOW
• 金额: $ 50.57万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10264623
• 关键词: Address; Advisory Committees; Advocate; Alzheimer' s Disease; Alzheimer' s disease related dementia; Area; Automobile Driving; Budgets; Clinical; Clinical Trials; Consent; Consultations; Data; Development; Education; Ensure; Faculty; Fund Raising; Funding; Genomics; Goals; Government; Grant; Growth; Infrastructure; Intervention Studies; Kansas; Metabolism; Mitochondria; Molecular; Monitor; Patient Care; Pilot Projects; Play; Prevention Research; Prevention strategy; Productivity; Program Development; Progress Reports; Public Relations; Research; Research Personnel; Resources; Role; Services; Site Visit; Strategic Planning; United States National Institutes of Health; Universities; Visit; Work; aging brain; base; design; effective therapy; empowered; falls; lifestyle intervention; meetings; mitochondrial metabolism; neuroimaging; operation; programs; ranpirnase; recruit; success; symposium; treatment strategy

ABSTRACT: ADMINISTRATIVE CORE The Administrative Core oversees operational and strategic planning for the University of Kansas Alzheimer's Disease Research Center (KU ADRC). Over a decade of P30 support, the Core managed growth that saw us become a leader in AD mitochondria/metabolism, lifestyle intervention, and prevention research. Supporting these programs required us to develop and implement unique infrastructure that promotes specialized molecular, clinical trial, recruitment, education, and patient care initiatives. In addition to defining Center strategy, the Core manages the resources needed to support our investigators. This includes biospecimen procurement plans; consent and compliance requirements; ensuring biospecimen storage; and facilitating access to biospecimens, data, consultation, and other Center services. We advise our other cores, monitor their productivity, and promote their seamless and synergistic cooperation. We verify NIA programmatic obligations are efficiently met and maintain Internal and External Advisory Committees. Up to this point we ran an immensely successful pilot project program; from 2011 through 2019 we saw 27 of 40 (68%) of our pilot recipients receive external grant support. The Core ensures all KU ADRC components receive adequate financial resources. Beyond managing our P30 budget, we accomplish this by identifying and procuring dollars from institutional ADRC stakeholders, developing philanthropy, and submitting P30 supplements. Whether designing strategy, tracking down dollars, identifying space, building resources, developing investigators, or growing the Center and advancing its agenda, the Administrative Core plays an integral role in both short-and-long term KU ADRC successes. Over the past 10 years we clearly transformed AD, AD-related, and brain aging research at the University of Kansas. During our next cycle we will continue our trajectory of guided, strategic growth that advances the AD research field and moves us closer to effective treatments and prevention strategies. We will accomplish these goals by focusing on a defined set of specific aims that include: (1) Managing infrastructure and routine operations; (2) Developing and empowering intellectual assets; and (3) Defining goals and amplifying impact.

摘要：行政核心 行政核心负责监督堪萨斯大学的运营和战略规划 阿尔茨海默病研究中心（KU ADRC）。经过十多年的P30支持，Core成功实现了增长 这使我们成为AD线粒体/代谢，生活方式干预和预防研究的领导者。 支持这些计划需要我们开发和实施独特的基础设施， 专业分子、临床试验、招募、教育和患者护理计划。 除了定义中心战略外，核心还管理支持我们的 investigators.这包括生物标本采购计划;同意和合规要求;确保 生物样本存储;以及方便访问生物样本、数据、咨询和其他中心服务。 我们为其他核心提供建议，监控他们的生产力，并促进他们的无缝协同合作。 我们验证NIA计划义务是否得到有效履行，并保持内部和外部咨询 委员会。到目前为止，我们在2011年至2019年期间开展了一个非常成功的试点项目计划。 我们看到40名试点受援者中有27名（68%）获得了外部赠款支持。核心确保所有KU ADRC 各组成部分获得充足的财政资源。除了管理我们的P30预算外，我们还通过以下方式实现这一目标： 从ADRC机构利益相关者那里确定和获得资金，发展慈善事业，并提交 P30补充剂 无论是设计战略、追踪资金、确定空间、建设资源、开发 调查员，或发展中心和推进其议程，行政核心发挥着不可或缺的作用， 短期和长期的KU ADRC成功。在过去的10年里，我们清楚地改变了广告，广告相关， 以及堪萨斯大学的大脑老化研究。在我们的下一个周期，我们将继续我们的轨道， 指导性的战略增长，推进AD研究领域，使我们更接近有效的治疗方法， 预防战略。我们将通过专注于一系列明确的具体目标来实现这些目标， 包括：（1）管理基础设施和日常业务;（2）发展和增强知识产权 资产;（3）确定目标，扩大影响。