Research Training in Pediatric Critical Care Medicine

儿科重症监护医学研究培训

• 批准号: 10593956
• 负责人: JEFFREY R FINEMAN
• 金额: $ 14.29万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-15 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10593956
• 关键词: Childhood; Critical Care; Medicine; Research Training

ABSTRACT The need for increased academic physician-scientists in Pediatric Critical Care Medicine, and collaborative rigorous investigation of new treatment modalities with focus on pathobiology, health disparities, and long-term morbidities, is clear. This renewal application requests the resources to continue our four-year post-doctoral research training program in Pediatric Critical Care Medicine within the Department of Pediatrics at the University of California, San Francisco. The goal of the program, which began in 2006, is to increase the number of highly trained, successfully funded and sustainable pediatric critical care physician-scientists, who will perform high level laboratory, clinical-translational, and/or health services research that will ultimately improve our understanding of the pathobiology of critical illness, improve short and long-term outcomes, and reduce the incidence of children with residual disabilities and/or chronic disease. To this end, this program aims to provide comprehensive science training and mentoring career development for pediatricians with an M.D. or M.D./Ph.D. degree who commit themselves to an academic career with a strong research component. The key elements of the training program are (1) a mentored research experience, (2) scientific course work, (3) career development workshops, (4) interdisciplinary experiences, (5) continuing review and evaluation. The centerpiece of the program is the continuation of a 4-year fellowship training program, with two years devoted to intense research training in basic laboratory, clinical-translational, health services, or epidemiologic science related to pediatric critical care disease. A large number of exceptionally qualified faculty have committed their support as mentors for fellows supported by the proposed training grant. These faculty are affiliated with several of the UCSF campuses and organized research units and programs (i.e., the Cardiovascular Research Institute and the Department of Epidemiology and Biostatistics), and several UCSF clinical campuses including UCSF Benioff Children’s Hospitals in SF and Oakland, and the Zuckerberg SF General Hospital and Trauma Center. All fellows will take courses in (1) Responsible conduct in research; (2) Scientific writing; (3) Art of lecturing; (4) Statistical Analysis; and (5) Bioinformatics. In addition, all trainees and faculty will complete DEI training. A strong Trainees Mentoring Program will support post-doctoral fellows in their training and career development. Mentors will meet with the fellow on a regular basis, to assist him/her in setting and monitoring training and career goals. The program has a strong track record in recruiting and training pediatric sub-specialists. Amongst the 16 trainees who have completed training, 15 career development awards have been received. In addition, our first two trainees have received RO1 funding, and 15 of the 16 continue in full-time academic faculty appointments. Thus, the rationale for this renewal is based on the well-documented need for well-designed training programs to prepare pediatric-scientists for a sustained productive career in Pediatric Critical Care research and the fact that UCSF has the vision, experience and infrastructure to train the next generation of leaders in pediatric science.

摘要 在儿科重症监护医学领域需要更多的学术内科医生和科学家，并合作 对新的治疗方式进行严格的调查，重点是病理生物学、健康差距和长期 病态，是显而易见的。这份续签申请需要资源来继续我们四年的博士后课程 大学儿科儿科危重病医学研究培训计划 加利福尼亚州，旧金山。这项始于2006年的计划的目标是增加高度 训练有素、资助成功、可持续的儿科重症监护内科医生-科学家，他们将表现出色 实验室水平、临床翻译和/或医疗服务研究，最终将改善我们的 了解危重疾病的病理生物学，改善短期和长期结果，并减少 残障儿童和/或慢性病儿童的发病率。为此，该计划旨在提供 为拥有医学博士学位或医学博士学位的儿科医生提供全面的科学培训和指导职业发展。 学位，致力于学术事业，具有很强的研究成分。的关键要素 培训计划是(1)有指导的研究经验，(2)科学课程工作，(3)职业发展 讲习班，(4)跨学科经验，(5)持续审查和评价。该中心的核心是 该计划是为期四年的奖学金培训计划的继续，其中两年致力于密集的研究 与儿科相关的基础实验室、临床翻译、卫生服务或流行病学方面的培训 重症监护疾病。一大批非常合格的教职员工承诺支持他们担任导师。 由拟议的培训补助金资助的研究员。这些教员隶属于加州大学旧金山分校的几个 并组织了研究单位和方案(即心血管研究所和 流行病学和生物统计学系)，以及包括加州大学伯尼奥夫分校在内的几个加州大学临床分校 位于旧金山和奥克兰的儿童医院，以及扎克伯格旧金山综合医院和创伤中心。所有研究员 将学习以下课程：(1)负责任的研究行为；(2)科学写作；(3)讲课艺术；(4)统计学 分析；(5)生物信息学。此外，所有学员和教职员工将完成Dei培训。实力雄厚的实习生 导师计划将支持博士后研究员的培训和职业发展。导师们将会面 定期与研究员合作，协助他/她制定和监督培训和职业目标。这个 该计划在招募和培训儿科分科专家方面有着良好的记录。在16名实习生中 完成培训的人员，获得了15个职业发展奖。另外，我们的前两个 学员已获得RO1资助，16名学员中有15名继续担任全职教职。因此， 这种更新的理由是基于对精心设计的培训计划的良好记录的需求，以 让儿科科学家为在儿科重症监护研究中持续富有成效的职业生涯做好准备，以及 加州大学旧金山分校拥有培养下一代儿科科学领导者的远见、经验和基础设施。

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有先见之明的预言家？

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Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.

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• DOI: 10.1097/pcc.0000000000002175
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• DOI: 10.1016/j.jtcvs.2013.08.009
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