Research Training in Pediatric Critical Care Medicine

儿科重症监护医学研究培训

• 批准号: 10593956
• 负责人: JEFFREY R FINEMAN
• 金额: $ 14.29万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-15 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10593956
• 关键词: Childhood; Critical Care; Medicine; Research Training

ABSTRACT The need for increased academic physician-scientists in Pediatric Critical Care Medicine, and collaborative rigorous investigation of new treatment modalities with focus on pathobiology, health disparities, and long-term morbidities, is clear. This renewal application requests the resources to continue our four-year post-doctoral research training program in Pediatric Critical Care Medicine within the Department of Pediatrics at the University of California, San Francisco. The goal of the program, which began in 2006, is to increase the number of highly trained, successfully funded and sustainable pediatric critical care physician-scientists, who will perform high level laboratory, clinical-translational, and/or health services research that will ultimately improve our understanding of the pathobiology of critical illness, improve short and long-term outcomes, and reduce the incidence of children with residual disabilities and/or chronic disease. To this end, this program aims to provide comprehensive science training and mentoring career development for pediatricians with an M.D. or M.D./Ph.D. degree who commit themselves to an academic career with a strong research component. The key elements of the training program are (1) a mentored research experience, (2) scientific course work, (3) career development workshops, (4) interdisciplinary experiences, (5) continuing review and evaluation. The centerpiece of the program is the continuation of a 4-year fellowship training program, with two years devoted to intense research training in basic laboratory, clinical-translational, health services, or epidemiologic science related to pediatric critical care disease. A large number of exceptionally qualified faculty have committed their support as mentors for fellows supported by the proposed training grant. These faculty are affiliated with several of the UCSF campuses and organized research units and programs (i.e., the Cardiovascular Research Institute and the Department of Epidemiology and Biostatistics), and several UCSF clinical campuses including UCSF Benioff Children’s Hospitals in SF and Oakland, and the Zuckerberg SF General Hospital and Trauma Center. All fellows will take courses in (1) Responsible conduct in research; (2) Scientific writing; (3) Art of lecturing; (4) Statistical Analysis; and (5) Bioinformatics. In addition, all trainees and faculty will complete DEI training. A strong Trainees Mentoring Program will support post-doctoral fellows in their training and career development. Mentors will meet with the fellow on a regular basis, to assist him/her in setting and monitoring training and career goals. The program has a strong track record in recruiting and training pediatric sub-specialists. Amongst the 16 trainees who have completed training, 15 career development awards have been received. In addition, our first two trainees have received RO1 funding, and 15 of the 16 continue in full-time academic faculty appointments. Thus, the rationale for this renewal is based on the well-documented need for well-designed training programs to prepare pediatric-scientists for a sustained productive career in Pediatric Critical Care research and the fact that UCSF has the vision, experience and infrastructure to train the next generation of leaders in pediatric science.

摘要 需要增加儿科重症监护医学的学术医生-科学家， 严格研究新的治疗方式，重点关注病理生物学，健康差异和长期 疾病，是明确的。这一更新申请要求的资源，继续我们的四年博士后 该大学儿科系儿科重症监护医学研究培训项目 来自加州的弗朗西斯科。该计划于2006年开始，其目标是增加高度 经过培训，成功资助和可持续的儿科重症监护医生-科学家，他们将在 水平的实验室，临床转化和/或卫生服务研究，最终将提高我们的 了解危重病的病理生物学，改善短期和长期结果，并减少 患有残余残疾和/或慢性病的儿童的发病率。为此，该计划旨在提供 为儿科医生提供全面的科学培训和指导职业发展。或医学博士/博士 谁致力于自己的学术生涯与一个强大的研究组成部分。的关键要素 培训计划是（1）指导研究经验，（2）科学课程工作，（3）职业发展 讲习班，（4）跨学科的经验，（5）不断审查和评价。的核心 该计划是一个为期4年的奖学金培训计划的延续，其中两年用于深入研究 基础实验室、临床转化、卫生服务或与儿科相关的流行病学科学培训 重症监护疾病大量非常合格的教师承诺作为导师提供支持 为拟议培训补助金支助的研究员提供培训。这些教师隶属于加州大学旧金山分校的几个 校园和有组织的研究单位和计划（即，心血管研究所和 流行病学和生物统计学系）和几个UCSF临床校区，包括UCSF贝尼奥夫 旧金山和奥克兰的儿童医院，以及扎克伯格旧金山综合医院和创伤中心。全体院士 我将参加以下课程：（1）负责任的研究行为;（2）科学写作;（3）演讲艺术;（4）统计 （5）生物信息学。此外，所有学员和教师将完成DEI培训。一个强大的学员 导师计划将支持博士后研究员的培训和职业发展。导师们会见面 定期与学员进行交流，协助学员制定和监督培训和职业目标。的 该计划在招募和培训儿科专科医生方面拥有良好的记录。在16名学员中， 在完成培训后，获得了15个职业发展奖。此外，我们的前两个 受训人员获得了RO 1资助，16人中有15人继续担任全职学术教师。因此，在本发明中， 这种更新的理由是基于对设计良好的培训计划的需求， 准备儿科科学家在儿科重症监护研究和事实， UCSF拥有培养儿科科学下一代领导者的愿景，经验和基础设施。

项目成果

Validation of a self-efficacy instrument and its relationship to performance of crisis resource management skills.

• DOI: 10.1007/s10459-011-9274-7
• 发表时间: 2011-12
• 期刊: ADVANCES IN HEALTH SCIENCES EDUCATION
• 影响因子: 4
• 作者: Plant, Jennifer L.;van Schaik, Sandrijn M.;Sliwka, Diane C.;Boscardin, Christy K.;O'Sullivan, Patricia S.
• 通讯作者: O'Sullivan, Patricia S.

The Prescient Prognosticator? Hepatoma-derived Growth Factor in Pulmonary Hypertension.

有先见之明的预言家？

• DOI: 10.1164/rccm.201606-1159ed
• 发表时间: 2016
• 期刊: American journal of respiratory and critical care medicine
• 影响因子: 24.7
• 作者: Kameny,RebeccaJohnson;Fineman,JeffreyR
• 通讯作者: Fineman,JeffreyR

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.

• DOI: 10.1172/jci161077
• 发表时间: 2022-05-16
• 期刊: JOURNAL OF CLINICAL INVESTIGATION
• 影响因子: 15.9
• 作者: Bertero, Thomas;Lu, Yu;Annis, Sofia;Hale, Andrew;Bhat, Balkrishen;Saggar, Rajan;Saggar, Rajeev;Wallace, W. Dean;Ross, David J.;Vargas, Sara O.;Graham, Brian B.;Kumar, Rahul;Black, Stephen M.;Fratz, Sohrab;Fineman, Jeffrey R.;West, James D.;Haley, Kathleen J.;Waxman, Aaron B.;Chau, B. Nelson;Cottrill, Katherine A.;Chan, Stephen Y.
• 通讯作者: Chan, Stephen Y.

Clinical Characteristics, Major Morbidity, and Mortality in Trauma-Related Pediatric Acute Respiratory Distress Syndrome.

创伤相关小儿急性呼吸窘迫综合征的临床特征、主要发病率和死亡率。

• DOI: 10.1097/pcc.0000000000002175
• 发表时间: 2020
• 期刊: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
• 作者: Nair,AlisonB;Cohen,MitchellJ;Flori,HeidiR
• 通讯作者: Flori,HeidiR

Preoperative B-type natriuretic peptide levels are associated with outcome after total cavopulmonary connection (Fontan).

• DOI: 10.1016/j.jtcvs.2013.08.009
• 发表时间: 2014-07
• 期刊: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
• 影响因子: 6
• 作者: Radman, Monique;Keller, Roberta L.;Oishi, Peter;Datar, Sanjeev A.;Wellnitz, Kari;Azakie, Anthony;Hanley, Frank;Char, Danton;Hsu, Jong-Hau;Amrinovin, Rambod;Adatia, Ian;Fineman, Jeffrey R.
• 通讯作者: Fineman, Jeffrey R.