Research Training in Pediatric Critical Care Medicine

儿科重症监护医学研究培训

• 批准号: 10593956
• 负责人: JEFFREY R FINEMAN
• 金额: $ 14.29万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-15 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10593956
• 关键词: Childhood; Critical Care; Medicine; Research Training

ABSTRACT The need for increased academic physician-scientists in Pediatric Critical Care Medicine, and collaborative rigorous investigation of new treatment modalities with focus on pathobiology, health disparities, and long-term morbidities, is clear. This renewal application requests the resources to continue our four-year post-doctoral research training program in Pediatric Critical Care Medicine within the Department of Pediatrics at the University of California, San Francisco. The goal of the program, which began in 2006, is to increase the number of highly trained, successfully funded and sustainable pediatric critical care physician-scientists, who will perform high level laboratory, clinical-translational, and/or health services research that will ultimately improve our understanding of the pathobiology of critical illness, improve short and long-term outcomes, and reduce the incidence of children with residual disabilities and/or chronic disease. To this end, this program aims to provide comprehensive science training and mentoring career development for pediatricians with an M.D. or M.D./Ph.D. degree who commit themselves to an academic career with a strong research component. The key elements of the training program are (1) a mentored research experience, (2) scientific course work, (3) career development workshops, (4) interdisciplinary experiences, (5) continuing review and evaluation. The centerpiece of the program is the continuation of a 4-year fellowship training program, with two years devoted to intense research training in basic laboratory, clinical-translational, health services, or epidemiologic science related to pediatric critical care disease. A large number of exceptionally qualified faculty have committed their support as mentors for fellows supported by the proposed training grant. These faculty are affiliated with several of the UCSF campuses and organized research units and programs (i.e., the Cardiovascular Research Institute and the Department of Epidemiology and Biostatistics), and several UCSF clinical campuses including UCSF Benioff Children’s Hospitals in SF and Oakland, and the Zuckerberg SF General Hospital and Trauma Center. All fellows will take courses in (1) Responsible conduct in research; (2) Scientific writing; (3) Art of lecturing; (4) Statistical Analysis; and (5) Bioinformatics. In addition, all trainees and faculty will complete DEI training. A strong Trainees Mentoring Program will support post-doctoral fellows in their training and career development. Mentors will meet with the fellow on a regular basis, to assist him/her in setting and monitoring training and career goals. The program has a strong track record in recruiting and training pediatric sub-specialists. Amongst the 16 trainees who have completed training, 15 career development awards have been received. In addition, our first two trainees have received RO1 funding, and 15 of the 16 continue in full-time academic faculty appointments. Thus, the rationale for this renewal is based on the well-documented need for well-designed training programs to prepare pediatric-scientists for a sustained productive career in Pediatric Critical Care research and the fact that UCSF has the vision, experience and infrastructure to train the next generation of leaders in pediatric science.

抽象的 需要增加儿科重症监护医学领域的学术医师科学家和协作 对新的治疗方式进行严格研究，重点关注病理学、健康差异和长期治疗 发病率，一目了然。此续签申请需要资源来继续我们四年的博士后研究 大学儿科系儿科重症监护医学研究培训项目 加利福尼亚州、旧金山。该计划于 2006 年开始实施，其目标是增加高水平人才的数量。 训练有素、成功资助和可持续的儿科重症监护医师科学家，他们将表现出色 水平实验室、临床转化和/或健康服务研究，最终将改善我们的 了解危重疾病的病理学，改善短期和长期结果，并减少 患有残余残疾和/或慢性疾病的儿童的发生率。为此，该计划旨在提供 为拥有医学博士或医学博士/博士学位的儿科医生提供全面的科学培训和职业发展指导。 致力于从事具有强大研究成分的学术职业的学位。的关键要素 培训计划包括 (1) 指导研究经验，(2) 科学课程作业，(3) 职业发展 研讨会，(4) 跨学科经验，(5) 持续审查和评估。的核心部分是 该计划是为期 4 年的奖学金培训计划的延续，其中两年致力于深入研究 与儿科相关的基础实验室、临床转化、卫生服务或流行病学方面的培训 重症监护疾病。一大批优秀的教师作为导师提供了支持 供受拟议培训补助金支持的研究员使用。这些教师隶属于 UCSF 的几所大学 校园和有组织的研究单位和项目（即心血管研究所和 流行病学和生物统计学系）以及加州大学旧金山分校的几个临床校区，包括加州大学旧金山分校贝尼奥夫分校 旧金山和奥克兰的儿童医院，以及扎克伯格旧金山综合医院和创伤中心。各位同仁 将参加 (1) 负责任的研究行为课程； (2) 科学写作； （三）讲授艺术； （四）统计 分析; (5)生物信息学。此外，所有学员和教师都将完成 DEI 培训。实力雄厚的练习生 指导计划将支持博士后研究员的培训和职业发展。导师将见面 定期与该研究员合作，协助他/她设定和监控培训和职业目标。这 该计划在招募和培训儿科专科医生方面拥有良好的记录。 16名练习生中 完成培训的人员已获得 15 项职业发展奖。另外，我们的前两个 学员已获得 RO1 资助，16 名学员中的 15 名继续担任全职学术教员。因此， 此次更新的理由是基于有充分记录的需要精心设计的培训计划，以 为儿科科学家在儿科重症监护研究领域的持续富有成效的职业生涯做好准备，事实上 加州大学旧金山分校拥有培养下一代儿科科学领导者的愿景、经验和基础设施。

项目成果

Validation of a self-efficacy instrument and its relationship to performance of crisis resource management skills.

• DOI: 10.1007/s10459-011-9274-7
• 发表时间: 2011-12
• 期刊: ADVANCES IN HEALTH SCIENCES EDUCATION
• 影响因子: 4
• 作者: Plant, Jennifer L.;van Schaik, Sandrijn M.;Sliwka, Diane C.;Boscardin, Christy K.;O'Sullivan, Patricia S.
• 通讯作者: O'Sullivan, Patricia S.

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.

• DOI: 10.1172/jci161077
• 发表时间: 2022-05-16
• 期刊: JOURNAL OF CLINICAL INVESTIGATION
• 影响因子: 15.9
• 作者: Bertero, Thomas;Lu, Yu;Annis, Sofia;Hale, Andrew;Bhat, Balkrishen;Saggar, Rajan;Saggar, Rajeev;Wallace, W. Dean;Ross, David J.;Vargas, Sara O.;Graham, Brian B.;Kumar, Rahul;Black, Stephen M.;Fratz, Sohrab;Fineman, Jeffrey R.;West, James D.;Haley, Kathleen J.;Waxman, Aaron B.;Chau, B. Nelson;Cottrill, Katherine A.;Chan, Stephen Y.
• 通讯作者: Chan, Stephen Y.

The Prescient Prognosticator? Hepatoma-derived Growth Factor in Pulmonary Hypertension.

有先见之明的预言家？

• DOI: 10.1164/rccm.201606-1159ed
• 发表时间: 2016
• 期刊: American journal of respiratory and critical care medicine
• 影响因子: 24.7
• 作者: Kameny,RebeccaJohnson;Fineman,JeffreyR
• 通讯作者: Fineman,JeffreyR

Clinical Characteristics, Major Morbidity, and Mortality in Trauma-Related Pediatric Acute Respiratory Distress Syndrome.

创伤相关小儿急性呼吸窘迫综合征的临床特征、主要发病率和死亡率。

• DOI: 10.1097/pcc.0000000000002175
• 发表时间: 2020
• 期刊: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
• 作者: Nair,AlisonB;Cohen,MitchellJ;Flori,HeidiR
• 通讯作者: Flori,HeidiR

Preoperative B-type natriuretic peptide levels are associated with outcome after total cavopulmonary connection (Fontan).

• DOI: 10.1016/j.jtcvs.2013.08.009
• 发表时间: 2014-07
• 期刊: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
• 影响因子: 6
• 作者: Radman, Monique;Keller, Roberta L.;Oishi, Peter;Datar, Sanjeev A.;Wellnitz, Kari;Azakie, Anthony;Hanley, Frank;Char, Danton;Hsu, Jong-Hau;Amrinovin, Rambod;Adatia, Ian;Fineman, Jeffrey R.
• 通讯作者: Fineman, Jeffrey R.