HD2A RASC-SUD Implementation Support Core

HD2A RASC-SUD 实施支持核心

• 批准号: 10596437
• 负责人: Sara J. Becker
• 金额: $ 59.12万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10596437
• 关键词: Action Research; Adoption; Advocacy; African American population; American; Asian Americans; Behavior Therapy; Black race; COVID-19 pandemic; Caring; Catalogs; Clinical Trials Network; Communities; Continuity of Patient Care; Data; Death Rate; Dissemination and Implementation; Engineering; Evaluation; Faculty; Funding; Goals; Harm Reduction; Healthcare; Healthcare Systems; Helping to End Addiction Long-term; Intervention; Investments; Justice; Lead; Leadership; Learning; Link; Measures; Mediation; Methodology; Methods; Motivation; National Institute of Drug Abuse; Native Americans; Native Hawaiian; Needles; Not Hispanic or Latino; Opioid; Overdose; Overdose reduction; Pacific Islander; Pain; Pharmaceutical Preparations; Pharmacology; Phase; Policies; Prevention; Public Health; Public Health Practice; Publications; Recovery Support; Research; Research Institute; Research Personnel; Resources; Role; Science; Scientist; Services; Substance Use Disorder; System; Technology Transfer; Time; Translating; Translational Research; Uninsured; United States National Institutes of Health; United States Substance Abuse and Mental Health Services Administration; addiction; base; caucasian American; dissemination science; evidence base; gaps in access; health equity; implementation facilitation; implementation intervention; implementation measures; implementation outcomes; implementation research; implementation science; implementation strategy; improved; innovation; knowledge base; marginalized population; opioid use disorder; overdose death; overdose prevention; overdose risk; program dissemination; psychosocial; resource guides; shared decision making; social stigma; substance use treatment; symposium

This study is part of the NIH’s Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative bolsters research across NIH to improve treatment for opioid misuse and addiction and to develop concrete strategies capable of providing rapid and durable solutions to the opioid crisis. SUD IMPLEMENTATION SUPPORT CORE: PROJECT SUMMARY/ABSTRACT Drug overdose fatalities have continued to rise despite massive federal investment in developing and disseminating evidence-based pharmacological and behavioral interventions for substance use disorders (SUDs). Attempts to move the needle on overdose deaths have stalled because of challenges translating research knowledge and evidence-based SUD interventions into public health practice. Access to evidence- based SUD interventions remains woefully limited throughout the U.S. health care system, particularly for historically marginalized populations such as Black/African-Americans, Native Hawaiians/Pacific Islanders, Asian Americans, and the uninsured. Equitable translation of research findings into practice is the domain of dissemination and implementation (D&I) science. A core component of the HD2A Research Adoption Support Center (RASC), the SUD Implementation Support (SUD-IS) Core will bring the best of D&I science to the Innovation Projects to guide the selection, implementation, and sustainment of evidence-based, locally appropriate SUD interventions to reduce overdose risk in hard hit communities. Core leadership will unify implementation scientists and SUD researchers - with the proximal goal of enhancing the impact of the Innovation Projects and the ultimate goal of improving public health - by leveraging cutting-edge D&I measures and methods, and capitalizing on our team’s commitment to team science. Thematically and operationally in tandem with the RASC and other cores, the SUD-IS Core will elevate the Innovation Projects through dynamic and iterative phases of ASSESS, ASSIST, and ADVANCE. We will first ASSESS the current state of evidence for SUD interventions in order to: a) develop a systematic catalog of evidence-based and emerging practices; and b) develop an SUD Intervention D&I Resource Guide for the Innovation Projects and any SUD intervention implementation project based on five key D&I constructs (e.g., contextual determinants, evidentiary support for the intervention, stakeholder engagement, implementation strategies, and implementation outcomes including equity and stigma). We will then ASSIST the Innovation Projects using information gathered in the ASSESS phase in order to: a) enhance motivation to enhance their studies with tailored D&I approaches that draw upon Core expertise; b) provide a D&I Implementation Support Plan and use a shared decision-making approach to determine how best to offer technical assistance; and c) co-lead the RASC Learning Collaborative. Finally, we will ADVANCE the Innovation Projects’ activities with respect to sustainment, equity, and stigma reduction: linking projects with the field at large, promoting impacts on policy/financing and facilitating ongoing stakeholder engagement towards advocacy. Perfectly aligned with the RASC, together we take a major step toward closing the persistent and inequitable gap of access to proven pharmacologic and psychosocial treatments for SUD.

这项研究是 NIH 帮助消除成瘾长期 (HEAL) 计划的一部分，该计划旨在加快科学解决国家阿片类药物公共卫生危机的速度。 NIH HEAL Initiative 支持 NIH 的研究，以改善阿片类药物滥用和成瘾的治疗，并制定能够为阿片类药物危机提供快速、持久解决方案的具体策略。 SUD 实施支持核心：项目摘要/摘要 尽管联邦投入巨资开发和传播针对药物滥用障碍 (SUD) 的循证药理学和行为干预措施，但药物过量死亡人数仍在持续上升。由于将研究知识和基于证据的 SUD 干预措施转化为公共卫生实践方面存在挑战，解决药物过量死亡问题的尝试已陷入停滞。令人遗憾的是，在整个美国医疗保健系统中，获得基于证据的 SUD 干预措施仍然受到严重限制，特别是对于历史上被边缘化的人群，如黑人/非裔美国人、夏威夷原住民/太平洋岛民、亚裔美国人和没有保险的人。将研究成果公平地转化为实践是传播和实施 (D&I) 科学的领域。作为 HD2A 研究采用支持中心 (RASC) 的核心组成部分，SUD 实施支持 (SUD-IS) 核心将为创新项目带来最好的 D&I 科学，以指导选择、实施和维持基于证据的、适合当地的 SUD 干预措施，以减少重灾区的用药过量风险。核心领导层将通过利用尖端的 D&I 措施和方法，并利用我们团队对团队科学的承诺，团结实施科学家和 SUD 研究人员，其近期目标是增强创新项目的影响，最终目标是改善公众健康。在主题和操作上，SUD-IS 核心将与 RASC 和其他核心相结合，通过动态和迭代的 ASSESS、ASSIST 和 ADVANCE 阶段来提升创新项目。我们将首先评估 SUD 干预措施的证据现状，以便： a) 制定基于证据和新兴实践的系统目录； b) 根据五个关键的 D&I 结构（例如背景决定因素、干预的证据支持、利益相关者参与、实施策略以及包括公平和耻辱在内的实施结果），为创新项目和任何 SUD 干预实施项目制定 SUD 干预 D&I 资源指南。然后，我们将使用在评估阶段收集的信息协助创新项目，以便： a) 通过利用核心专业知识的定制 D&I 方法来增强加强研究的动力； b) 提供 D&I 实施支持计划并使用共同决策方法来确定如何最好地提供技术援助； c) 共同领导 RASC 学习协作组织。最后，我们将推进创新项目在维持、公平和减少耻辱方面的活动：将项目与整个领域联系起来，促进对政策/融资的影响，并促进利益相关者持续参与宣传。我们与 RASC 完全一致，共同朝着缩小 SUD 获得经过验证的药物和心理社会治疗方面持续且不公平的差距迈出了重要一步。