Aging in Puerto Rico: Longitudinal Follow-Up of the PREHCO Study

波多黎各的老龄化：PREHCO 研究的纵向追踪

• 批准号: 10600164
• 负责人: Michael Gabriel Crowe
• 金额: $ 13.28万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10600164
• 关键词: Adult; Age; Aging; Archives; Area; Buffers; Categories; Characteristics; Chronic; Chronic Disease; Cognitive; Control Locus; Cross-Cultural Comparison; Data; Data Collection; Disasters; Elderly; Emotional Stability; Event; Exposure to; Family; Funding; Funding Opportunities; Future; Goals; Government; Hair; Health; Health and Retirement Study; Hispanic Populations; Home; Household; Hurricane; Hydrocortisone; Impaired cognition; Injury; International; Island; Life; Life Cycle Stages; Measures; Mental Health; Mexican Americans; Minority Groups; Outcome; Participant; Performance; Personal Satisfaction; Persons; Physical Function; Population Heterogeneity; Population Study; Proxy; Puerto Rican; Puerto Rico; Quality of life; Reporting; Resources; Risk; Sampling; Self Efficacy; Sister; Social Network; Social support; Stress; Subgroup; Survivors; Time; Translating; Visit; Vulnerable Populations; age group; aging population; base; biopsychosocial; biopsychosocial factor; cognitive function; cognitive testing; cohort; coping; cost effective; depressive symptoms; design; disability; enhancing factor; epidemiology study; experience; follow-up; genetic analysis; home test; hypothalamic-pituitary-adrenal axis; informant; insight; insurance claims; migration; mortality; novel; perceived stress; population based; repository; resilience; saliva sample; social; stressor; theories

PROJECT SUMMARY/ABSTRACT In the past decade, Puerto Rico has experienced rapid population aging, financial collapse, mass outward migration of younger people, and then Hurricane Maria. Now is an ideal time to build on the only population- based cohort of older adults in Puerto Rico, unique in having data on health and function prior to these major events. Households across Puerto Rico were visited to identify the first island-wide sample of adults age 60+ years for the Puerto Rican Elderly: Health Conditions (PREHCO) study. A wide range of measures relevant to health and aging, including in-home testing of cognitive and physical function, was collected at baseline (2002/2003) and four years later (2006/2007). We propose to gather two new waves of data related to aging, stress and health in a sample of approximately 1,000 PREHCO survivors. The current project will a) extend PREHCO follow-up to between 16 and 20 years after baseline; b) examine life course predictors of major aging outcomes, namely cognitive impairment, disability, and mortality; c) collect data on hurricane-related stressors and mental health; d) add hair cortisol as a marker of chronic hypothalamic pituitary adrenal (HPA) axis activation; and e) add cognitive and proxy informant measures that align with the Health and Retirement Study (HRS). Our project will enable the following specific aims: Aim 1. Examine longitudinal life course biopsychosocial predictors of cognitive health, cortisol levels, mental health, disability, and mortality 16-20 years after baseline. Aim 2. Examine cross-sectional associations between stressors, resilience-enhancing factors, perceived stress, cortisol, and health, as well as changes in health two years later. Aim 3. Increase utility of PREHCO for cross-cultural comparisons. Puerto Rico is an important part of the U.S. that has largely been omitted from U.S. population-based studies of aging. PREHCO participants are now age 76+ years and given accelerating mortality rates for this age group, our proposal to gather two new time points of follow-up data for PREHCO represents a time-limited opportunity to add to our knowledge about aging, stress, and health in an understudied and potentially vulnerable population.

项目摘要/摘要 在过去的十年中，波多黎各经历了迅速的人口衰老，金融崩溃，大规模向外 年轻人的迁移，然后是玛丽亚飓风。现在是建立唯一人群的理想时机 - 基于波多黎各的老年人队列，在这些专业之前拥有有关健康和功能的数据 事件。参观了波多黎各的家庭，以确定60岁以上成年人的第一个范围内样本 波多黎各老年人的年份：健康状况（PREHCO）研究。与 在基线时收集了健康和衰老，包括认知和身体机能的内部测试 （2002/2003）和四年后（2006/2007）。我们建议收集与衰老有关的两个新数据浪潮， 大约1,000名PreHCO幸存者的样本中的压力和健康。当前项目将a）扩展 基线后16至20年之间的PREHCO随访； b）检查主要衰老的生活课程预测指标 结果，即认知障碍，残疾和死亡率； c）收集有关飓风相关压力源的数据 和心理健康； d）添加头发皮质醇作为慢性下丘脑垂体肾上腺（HPA）轴的标记 激活; e）添加与健康和退休研究保持一致的认知和代理线人措施 （HRS）。我们的项目将实现以下特定目标：目标1。检查纵向生活课程 认知健康，皮质醇水平，心理健康，残疾和死亡率的生物心理社会预测指标16-20 基线后几年。目标2。检查压力源之间的横截面关联，增强弹性 因素，感知压力，皮质醇和健康以及两年后健康的变化。目标3。增加 Prehco用于跨文化比较的实用性。波多黎各是美国的重要组成部分 从美国衰老研究中省略了。 PREHCO参与者现在年龄在76岁以上，并且 鉴于该年龄段的加速死亡率，我们提出的提议收集两个新的随访时间点 PREHCO的数据代表了一个有时的机会，可以增加我们对衰老，压力和 在一个研究且潜在脆弱的人群中的健康状况。