Renovation of Core Laboratories for the DC Intellectual and Developmental Disabilities Research Center

华盛顿特区智力与发育障碍研究中心核心实验室改造

• 批准号: 10866636
• 负责人: Tarik F Haydar
• 金额: $ 674.91万
• 依托单位: CHILDREN'S NATIONAL AT WALTER REED, LLC
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2023-12-12
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10866636
• 关键词: Renovation; Core; Laboratories; DC; Intellectual

Project Summary Children’s National Hospital (CNH) proposes to relocate 15,520 GSF of advanced core facility research space in support of its NIH funded District of Columbia Intellectual and Developmental Disabilities Research Center (DC- IDDRC). The relocation and expansion of this program will be from CNH Sheikh Zayed campus to the new Children’s National Research and Innovation Campus located at the former Walter Reed Army Medical Center site in Northwest Washington, D.C., 4 miles from the hospital. The project involves renovation/modernization of one floor of the former Armed Forces Institute of Pathology building originally constructed in 1955. The total cost of this construction is estimated to be $9,446,951. This CO6 requests a budget of $8,000,000 with the remainder of the cost (approximately $1,446,951) being funded by CNH. This state-of-the-art core facility will allow the conduct and expansion of genetic and neuroscience research initiatives of the DC-IDDRC, an interdisciplinary and inter-institutional research center. The mission of this IDDRC is to improve the understanding and treatment of children with developmental disabilities, including autism, cerebral palsy, epilepsy, inherited metabolic disorders and intellectual disability. The new space will support 3 cores that will be accessible to investigators from the four institutions that comprise the DC-IDDRC: CNH, George Washington University (GW), Georgetown University and Howard University. The construction will also include shared hoteling laboratory space for DC-IDDRC investigators whose laboratories are not on- site but who are utilizing the core facility. The proposed DC-IDDRC cores consist of: 1) Cell and Tissue Microscopy, 2) Genomics and Bioinformatics, and 3) Induced Pluripotent Stem Cells (IPSC).

项目摘要 国立儿童医院(CNH)提议搬迁15,520 GSF的先进核心设施研究空间 为支持其由NIH资助的哥伦比亚特区智力和发育障碍研究中心 (DC-IDDRC)。该项目的搬迁和扩展将从CNH谢赫·扎耶德校区迁至 新的儿童国家研究和创新园区位于前沃尔特里德陆军医疗中心 中心位于华盛顿特区西北部，距离医院4英里。该项目涉及 原军队病理学院大楼一层翻新/现代化改造 它建于1955年。这项工程的总费用估计为9446 951美元。此CO6请求 预算8,000,000美元，其余费用(约1,446,951美元)由CNH提供资金。这 最先进的核心设施将允许进行和扩展遗传和神经科学研究 DC-IDDRC是一个跨学科和跨机构的研究中心的倡议。这件事的使命是 IDDRC旨在增进对发育障碍儿童的理解和治疗，包括 自闭症、脑瘫、癫痫、遗传性代谢障碍和智力残疾。新的空间将 支持3个核心，这3个核心将可供组成DC-IDDRC的四个机构的调查人员使用： CNH、乔治华盛顿大学(GW)、乔治城大学和霍华德大学。建筑工程 还将包括为DC-IDDRC调查人员提供共享酒店实验室空间，其实验室不在- 网站，但谁正在使用核心设施。建议的DC-IDDRC核心包括：1)细胞和组织 显微镜，2)基因组学和生物信息学，3)诱导多能干细胞(IPSC)。