Training to provide the knowledge, skills, and culture to the next generation of cardiovascular scientists
Training to provide the knowledge, skills, and culture to the next generation of cardiovascular scientists
批准号:
10602446
负责人:
Brandon J Biesiadecki
金额:
$36.56万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
未结题
起止时间:
2017-07-01 至 2027-06-30
中文摘要
项目总结
心血管疾病仍然是美国的头号死因。高效发展
未来识别和治疗心血管疾病的新诊断和治疗方法将需要高度
由最好的基础、翻译和临床研究人员组成的协作和多学科团队。至
要实现这一总体目标,心血管研究人员首先必须具备多学科知识
在高度跨学科、协作和翻译的团队中具有技能和工作能力,以高效地传递知识
从长凳到床边,到社区,再到后背。第二,获得最佳生产率,以实现
为了改善人群的心血管健康,至关重要的是要利用
整个科学工作者。我们已经建立了一个培训计划,以满足这两个未得到满足的需求,
最终需要以最佳方式培训和留住下一代最好的心血管研究人员。
该培训计划的目标是:
1.提供多方面的心血管研究培训,以便在协作、多学科的团队中工作
这将促进科学成果的有效转化,以改善人类健康。
2.通过培训提高优秀科研人员和领导者的数量
向所有受训人员宣传妇女,改善妇女成功的文化,并促进留住妇女
在心血管研究领域从事独立的科学事业。
除了高级心脏生理学和生物统计学课程,严谨性和可重复性,以及
负责任地开展科研培训,在第一届实施了几项创新计划活动
资金周期,以实现这些目标。领导技能和提高妇女地位研讨会提供了这两个方面
在博士前水平具有关键专业发展和领导技能的男性和女性,以提高
改变女性的职业轨迹,改变女性成功的文化,留住最好的科学研究人员
在职业生涯的后期阶段。这些研讨会还为学员提供了宝贵的网络机会,
杰出的来访心血管科学家。临床导师计划允许学员学习
临床医学中的语言和文化,并发展形成未来合作所需的技能
医生。分子和细胞心脏生理学正在进行的演示具有高度互动性
提高学员的研究和演示技能,强调严谨和
再现性。在这次更新中,我们将继续扩展这些计划,包括Career
导师制,以满足学员个性化的职业目标。在俄亥俄州立大学,我们有一个高度
协作和多学科科学基础设施,旨在支持
心血管研究、教育和培训。这个T32应用程序的导师都已确定
在各自领域的科学家,对培训充满热情,并致力于本培训计划的目标。
英文摘要
PROJECT SUMMARY
Cardiovascular disease remains the number one cause of death in the United States. The efficient development
of future novel diagnostics and therapies to identify and treat cardiovascular disease will require highly
collaborative and multi-disciplinary teams consisting of the best basic, translational and clinical investigators. To
achieve this overarching goal, it will first be essential for cardiovascular researchers to possess multi-disciplinary
skills and work in highly inter-disciplinary, collaborative and translational teams to efficiently move knowledge
from the bench to the bedside, to the community and back. Second, to obtain optimal productivity towards
improving cardiovascular health of the population, it is essential to utilize the contributions from the best of the
entire scientific workforce. We have established a Training Program addressing these two unmet needs that will
ultimately be required to optimally train and retain the next generation of the best cardiovascular investigators.
The goals of this Training Program are:
1. To provide multi-faceted cardiovascular research training to work in collaborative, multidisciplinary teams
that will facilitate efficient translation of scientific findings to improve human health.
2. To enhance the numbers of outstanding researchers and leaders by providing training for the advancement
of women to all trainees, improving the culture for women to succeed, and promoting the retention of women
in independent scientific careers in cardiovascular research.
In addition to advanced Cardiac Physiology and Biostatistics coursework, Rigor and Reproducibility, and
Responsible Conduct of Research Training, several innovative Program Activities were implemented in the first
funding cycle to achieve these goals. Leadership Skills and Advancement of Women workshops supply both
men and women with key professional development and leadership skills at the predoctoral level to improve the
career trajectory of women and change the culture for women to succeed to retain the best scientific investigators
at later career stages. These workshops also provide valuable networking opportunities for trainees with
prominent visiting cardiovascular scientists. The Clinical Mentorship program allows trainees to learn the
language and culture within clinical medicine and to develop the skills needed to form future collaborations with
physicians. Molecular and Cellular Cardiophysiology research-in-progress presentations are highly interactive
and improve both the research and presentation skills of the trainees as well as emphasize rigor and
reproducibility. In this renewal, we will continue to expand upon these programs by also including Career
Mentorship to meet the individualized career goals of trainees. At The Ohio State University, we have a highly
collaborative and multi-disciplinary scientific infrastructure that has been created to support translational
cardiovascular research, education, and training. The mentors on this T32 application are all established
scientists in their field, have a passion for training, and are committed to the goals of this Training program.
期刊论文(15)
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Loss of ADAMTS19 causes progressive non-syndromic heart valve disease.
ADAMTS19 的缺失会导致进行性非综合征性心脏瓣膜疾病。
DOI:
10.1038/s41588-019-0536-2
发表时间:
2020
期刊:
Nature genetics
影响因子:
30.8
作者:
[Wünnemann,Florian, Ta-Shma,Asaf, Preuss,Christoph, Leclerc,Severine, vanVliet,PatrickPiet, Oneglia,Andrea, Thibeault,Maryse, Nordquist,Emily, Lincoln,Joy, Scharfenberg,Franka, Becker-Pauly,Christoph, Hofmann,Philipp, Hoff,Kirstin, Audain,E]
通讯作者:
Audain,E
Non-contrast estimation of diffuse myocardial fibrosis with dual energy CT: A phantom study.
双重能量CT的弥漫性心肌纤维化的非对比度估计:一项幻影研究。
DOI:
10.1016/j.jcct.2017.12.002
发表时间:
2018-01
期刊:
Journal of cardiovascular computed tomography
影响因子:
5.4
作者:
[Kumar V, McElhanon KE, Min JK, He X, Xu Z, Beck EX, Simonetti OP, Weisleder N, Raman SV]
通讯作者:
Raman SV
DOI:
10.1161/circimaging.117.005447
发表时间:
2017-11
期刊:
Circulation. Cardiovascular imaging
影响因子:
--
作者:
[Kumar V, Hsueh WA, Raman SV]
通讯作者:
Raman SV
DOI:
10.1016/j.hfc.2022.02.003
发表时间:
2022-07
期刊:
HEART FAILURE CLINICS
影响因子:
3.4
作者:
[Scott, Shane S., Greenlee, Ashley N., Matzko, Anna, Stein, Matthew, Naughton, Michael T., Zaramo, Taborah Z., Schwendeman, Ethan J., Mohammad, Somayya J., Diallo, Mamadou, Revan, Rohith, Shimmin, Gabriel, Tarun, Shwetabh, Ferrall, Joel, Ho, Thai H., Smith, Sakima A.]
通讯作者:
Smith, Sakima A.
DOI:
10.3389/fcvm.2021.681948
发表时间:
2021
期刊:
Frontiers in cardiovascular medicine
影响因子:
3.6
作者:
[Breikaa RM, Lilly B]
通讯作者:
Lilly B
共 10 条
Troponin I phosphorylation as a novel novel cardiac inotrope
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批准号:10660193
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项目类别:
-
资助金额:$67.12万
-
财政年份:2023
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负责人:Brandon J Biesiadecki
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依托单位:
Training to provide the knowledge, skills, and culture to the next generation of cardiovascular scientists
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批准号:10331226
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项目类别:
-
资助金额:$35.74万
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财政年份:2017
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负责人:Brandon J Biesiadecki
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依托单位:
Integrated crosstalk of thin filament post-translational modifications
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批准号:9061802
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项目类别:
-
资助金额:$38.5万
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财政年份:2013
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负责人:Brandon J Biesiadecki
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依托单位:
Integrated crosstalk of thin filament post-translational modifications
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批准号:8726470
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项目类别:
-
资助金额:$37.73万
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财政年份:2013
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负责人:Brandon J Biesiadecki
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依托单位:
Integrated crosstalk of thin filament post-translational modifications
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批准号:8851003
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项目类别:
-
资助金额:$6.43万
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财政年份:2013
-
负责人:Brandon J Biesiadecki
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依托单位:
Integrated crosstalk of thin filament post-translational modifications
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批准号:8504053
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项目类别:
-
资助金额:$36.55万
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财政年份:2013
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负责人:Brandon J Biesiadecki
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依托单位:
Integrated Crosstalk of Thin Filament Post-translational Modifications
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批准号:9448622
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项目类别:
-
资助金额:$38.98万
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财政年份:2013
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负责人:Brandon J Biesiadecki
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依托单位:
Integrated Crosstalk of Thin Filament Post-translational Modifications
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批准号:10192786
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项目类别:
-
资助金额:$39.0万
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财政年份:2013
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负责人:Brandon J Biesiadecki
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依托单位:
Post-translational Modification in Cardiac Muscle
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批准号:8115759
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项目类别:
-
资助金额:$24.9万
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财政年份:2009
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负责人:Brandon J Biesiadecki
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依托单位:
Post-translational Modification in Cardiac Muscle
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批准号:7939634
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项目类别:
-
资助金额:$24.9万
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财政年份:2009
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负责人:Brandon J Biesiadecki
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依托单位:
Post-translational Modification in Cardiac Muscle
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批准号:7935758
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项目类别:
-
资助金额:$24.9万
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财政年份:2009
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负责人:Brandon J Biesiadecki
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依托单位:
The Role of Tropomyosin Post-translational Modification in Cardiac Muscle
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批准号:7363212
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项目类别:
-
资助金额:$9.0万
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财政年份:2008
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负责人:Brandon J Biesiadecki
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依托单位:
The Role of Tropomyosin Post-translational Modification in Cardiac Muscle
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批准号:7628088
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项目类别:
-
资助金额:$9.0万
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财政年份:2008
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负责人:Brandon J Biesiadecki
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依托单位:
The role of tropomyosin phosphorylation in muscle.
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批准号:7207942
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项目类别:
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资助金额:$5.04万
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财政年份:2005
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负责人:Brandon J Biesiadecki
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依托单位:
The role of tropomyosin phosphorylation in muscle.
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批准号:6994009
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项目类别:
-
资助金额:$4.83万
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财政年份:2005
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负责人:Brandon J Biesiadecki
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依托单位:
海外基金