ISU VDL Ambient Ionization Equipment Proposal

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2022 Vet-LIRN Grant for Ambient Ionization Equipment Project Summary: The purpose of this application is to purchase Coated Blade Spray (CBS) equipment for mass spectrometry analysis. As analytical technologies improve it is essential for labs to have new and improved analytical equipment. Coated Blade Spray mass spectrometry (CBS-MS) is an approximately 8 year-old analytical technology that allows for the rapid analysis of several types of samples in minutes. The Coated Blade Spray ionization source is interfaced directly with the mass spectrometer and provides an ambient ionization platform for multiple sample types and compounds. The time-consuming chromatography step of traditional liquid chromatography mass spectrometry (LC-MS) analysis is eliminated with CBS-MS. The total analysis time for samples with CBS-MS is under 2 minutes per sample. This new analytical technology would greatly enhance the capacity of both the ISU VDL analytical laboratory and the Vet-LIRN network.