2023 Epithelial Differentiation and Keratinization GRC & GRS

项目摘要 2023年戈登上皮分化和角化研究会议（GRC-EDK） 在上皮生物学的首要国际会议，证明了国际定期出席 这一领域的领导者，申请人的规模和压倒性的积极与会者评论。关于GRC- EDK自1979年以来每两年举办一次，展示最新的概念和技术进步 一直在推动该领域的发展，对人类健康产生直接影响。到 保持过去会议的卓越品质，2023年的这次会议题为"创新机制， 调节上皮生物学及其在生理学，衰老和疾病中的意义"的目的是带来 在干细胞生物学，癌症，再生医学，免疫， 衰老，表观遗传学，皮肤病，新的单细胞分子技术，全球基因组学，和新的 治疗本次会议的目标和长期计划是提出和讨论最新的 通过正式和非正式讨论， 为未来的发现和新的治疗方法创造协同团队方法的新机会 展望未来，推动整个领域的发展。科学的卓越植根于多样性， 尊重主题、地点和性别。超过20%的演讲者来自直接领域之外，85%没有 在2019年的会议上发言，超过30%的口头报告将从提交的摘要中选出， 容纳最新的激动人心的故事，并确保为早期职业生涯提供充足的演讲机会 调查员和学员。2023年会议相对孤立的位置和住宅性质，以及 下午的非正式时间，最大限度地增加科学讨论、指导互动的机会， 新的合作。最后，会议第一天的一个电源小时将催化重要的讨论 寻找识别和解决科学歧视的方法。2023年，我们将继续致力于 通过第五届戈登上皮分化研究研讨会和 角化（GRS-EDK），紧接在GRC-EDK之前。组织和举办GRS会议 实习科学家提供了一个独特的机会，不仅讨论他们的科学在一个非正式的支持 此外，还可以与同龄人建立网络，并发展终身合作。GRS-EDK还将采用 职业指导小组讨论，特别强调向职业独立过渡， 学术界与工业界，以及性别和种族多样性在科学中的重要性。总的来说，这些 计划反映了NIAMS研究所通过三个基本领域执行的愿景：1）向前发展 皮肤生物学领域的前沿研究; 2）促进关键研究成果转化为临床 实践，以及3）促进早期研究人员和学员的职业生涯，以保持最高水平的 这一领域的创新。

Project Summary The 2023 Gordon Research Conference on Epithelial Differentiation and Keratinization (GRC-EDK) is the premier international meeting in epithelial biology, evidenced by the regular attendance of international leaders in this field, the size of its applicant pool and the overwhelmingly positive attendee reviews. The GRC- EDK has been held bi-annually since 1979 and showcases the latest conceptual and technological advances in epithelial biology which have consistently moved the field forward with direct impact on human health. To maintain the pre-eminent quality of past meetings, this meeting in 2023 entitled “Novel mechanisms of regulation in epithelial biology and their implication in physiology, aging and disease” aims to bring together preeminent speakers at the forefront of stem cell biology, cancer, regenerative medicine, immunity, aging, epigenetics, skin diseases, novel single cell molecular technologies, global genomics, and novel therapies. The objectives and long-term plans of this conference is to present and discuss the latest developments in these different fields of expertise through both formal and informal discussion as well as generate new opportunities of synergestic team approaches towards future discoveries and novel therapeutic prospects to advance the field as a whole. The excellence of the science is rooted into the diversity with respect to topic, location and gender. Over 20% of speakers are from outside the immediate field, 85% did not speak in the 2019 meeting, and over 30% of oral presentations will be selected from submitted abstracts to accommodate late breaking exciting stories and ensure plentiful speaking opportunities for early career investigators and trainees. The relatively isolated location and residential nature of the 2023 Conference, and the informal afternoon periods, maximize opportunities for scientific discussions, mentoring interactions and new collaborations. Finally, a power hour on the first day of the conference will catalyze important discussions for ways to recognize and tackle discriminations in science. For 2023, we will continue our commitment to trainee mentorship through the 5th Gordon Research Seminar on Epithelial Differentiation and Keratinization (GRS-EDK), immediately preceding the GRC-EDK. GRS meetings are organized and featured by trainee scientists providing a unique opportunity to not only discuss their science in an informal supportive setting but also to network with peers and develop life-long collaborations. The GRS-EDK will also feature a career mentoring panel discussion with special emphases on transitioning to career independence, careers in academia versus industry, and the importance of gender and racial diversity within science. Collectively, these programs reflect the vision of NIAMS institute executed through three fundamental areas 1) moving forward cutting edge research in the area of skin biology; 2) promoting translation of key research findings to clinical practice, and 3) furthering the careers of early stage investigators and trainees to maintain the highest level of innovation of this field.