Facing Eating Disorder Fears for Anorexia Nervosa: A Virtual Relapse Prevention Program Targeted at Approach and Avoidance Behaviors

面对饮食失调对神经性厌食症的恐惧:针对接近和回避行为的虚拟复发预防计划

基本信息

  • 批准号:
    10611448
  • 负责人:
  • 金额:
    $ 19.56万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-05-01 至 2025-04-30
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY/ABSTRACT Anorexia nervosa (AN) is chronic and disabling; most individuals never achieve full remission, even after acute treatment, and 50% of those who access acute treatment will relapse within 6- months of discharge. AN relapse-prevention treatments are urgently needed that can disrupt the persistent cycle of admission and discharge from acute treatment. Importantly, existing treatments do not differ from control treatments in the ability to alter cognitive-behavioral AN pathology, which is the primary remaining symptomatology at discharge from acute care. The inability to alter cognitive-behavioral pathology is a function of the limited availability of treatments that include skills training to promote behavior change in a “real-world” context, outside of treatment facilities. As such, relapse-prevention treatments should explicitly target core cognitive-behavioral pathology to facilitate approach behaviors (e.g., facing fear foods) in the real-world. Our scientific premise, developed from our past work, is that the application of a virtual format of Facing Eating Disorder Fears (FED-F) for AN will facilitate engagement in approach behaviors and minimize avoidance behaviors - improving outcomes, enhancing full recovery, and decreasing the likelihood of relapse. FED-F is a modular treatment that enhances exposure therapy with psychoeducation and cognitive skills teaching how to face fears of (a) food, (b) weight gain, (c) interoception/body, and (d) social situations. Our study goals are to (1) refine and test the acceptability and feasibility of FED-F delivered post-acute treatment as adjunctive to step-down specialty care, (2) test if this treatment outperforms treatment as usual (TAU), and (3) to examine if treatment targets our hypothesized mechanism of action: approach behaviors. These goals will lead to a highly deployable and accessible virtual treatment targeted at core AN mechanisms that predict relapse. The proposed research uses highly innovative methods; we will use an all-remote technology-based approach, combining a virtual, non- therapist assisted treatment with remote behavioral and momentary assessment of approach/avoidance behaviors. Specific aims are to (1) refine FED-F into a fully virtual format with input from patients and stakeholders and collect preliminary data (N=10) on its feasibility and acceptability, (2) conduct a small pilot RCT of FED-F (n=30) as compared to TAU (n=30), and (3) examine if FED-F targets approach/avoidance behaviors and test if this mechanism is associated with clinical outcomes. Ultimately, this proposal will lead to the creation and dissemination of a highly user-friendly, easily accessible and deployable intervention, delivered during a critical period of care, that can prevent AN relapse, which will decrease mortality, morbidity, and the high costs associated with chronic treatment.
项目摘要/摘要 神经性厌食症(AN)是慢性和致残性的;大多数人从未达到完全缓解, 即使在急性治疗后,50%接受急性治疗的患者会在6- 10天内复发。 数月的出院。迫切需要一种预防复发的治疗方法, 入院和出院急性治疗的持续周期。重要的是,现有 在改变认知行为AN的能力方面,治疗与对照治疗没有差异 病理学,这是从急性护理出院时的主要剩余病理学。的 无法改变认知行为病理是有限的可用性的函数, 包括技能培训在内的治疗,以促进“现实世界”背景下的行为改变, 在治疗设施之外。因此,预防复发的治疗应明确针对 促进接近行为的核心认知行为病理(例如,面对恐惧的食物) 现实世界我们的科学前提是,从我们过去的工作中发展出来的, 面向AN的进食障碍恐惧(FED-F)的虚拟格式将有助于参与 接近行为和尽量减少回避行为-改善结果,增强全面 恢复,并降低复发的可能性。FED-F是一种模块化治疗, 暴露疗法结合心理教育和认知技能,教授如何面对恐惧(a) 食物,(B)体重增加,(c)内感受/身体,和(d)社会情况。我们的研究目标是(1) 完善和测试FED-F提供的急性后治疗的可接受性和可行性, 拒绝逐步降低的专科护理,(2)测试这种治疗是否优于常规治疗 (TAU)和(3)检查治疗是否针对我们假设的作用机制:方法 行为。这些目标将导致一个高度可部署和可访问的虚拟治疗目标 预测复发的核心机制。这项研究采用了高度创新的 方法;我们将使用一个全远程技术为基础的方法,结合虚拟,非 治疗师辅助治疗,远程行为和瞬时评估 接近/回避行为。具体目标是(1)将FED-F改进为完全虚拟的格式 患者和利益相关者的输入,并收集其可行性的初步数据(N=10) 和可接受性,(2)进行FED-F(n=30)与TAU(n= 30)相比的小型试点RCT, 以及(3)检查FED-F是否针对接近/回避行为,并测试该机制是否 与临床结果相关。最终,这一提议将导致创建和 传播一种非常方便用户、容易获得和可部署的干预措施, 在护理的关键时期,这可以防止AN复发,这将降低死亡率, 发病率,以及与慢性治疗相关的高成本。

项目成果

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Cheri Alicia Levinson其他文献

Cheri Alicia Levinson的其他文献

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{{ truncateString('Cheri Alicia Levinson', 18)}}的其他基金

Longitudinal Personalized Dynamics Among Anorexia Nervosa Symptoms, Core Dimensions, and Physiology Predicting Suicide Risk
神经性厌食症症状、核心维度和预测自杀风险的生理学之间的纵向个性化动态
  • 批准号:
    10731597
  • 财政年份:
    2023
  • 资助金额:
    $ 19.56万
  • 项目类别:
Personalized Networks and Sensor Technology Algorithms of Eating Disorder Symptoms Predicting Eating Disorder Outcomes
个性化网络和传感器技术饮食失调症状的算法预测饮食失调的结果
  • 批准号:
    10652078
  • 财政年份:
    2023
  • 资助金额:
    $ 19.56万
  • 项目类别:
Innovations in Personalizing Treatment for Eating Disorders Using Idiographic Methods and the Impact of Personalization on Psychological, Physical, and Sociodemographic Outcomes
使用具体方法对饮食失调进行个性化治疗的创新以及个性化对心理、身体和社会人口学结果的影响
  • 批准号:
    10685796
  • 财政年份:
    2023
  • 资助金额:
    $ 19.56万
  • 项目类别:
Facing Eating Disorder Fears for Anorexia Nervosa: A Virtual Relapse Prevention Program Targeted at Approach and Avoidance Behaviors
面对饮食失调对神经性厌食症的恐惧:针对接近和回避行为的虚拟复发预防计划
  • 批准号:
    10425019
  • 财政年份:
    2022
  • 资助金额:
    $ 19.56万
  • 项目类别:
A Pilot Investigation of Network-Informed Personalized Treatment for Eating Disorders versus Enhanced Cognitive Behavioral Therapy and Dynamic Mechanisms of Change
饮食失调的网络信息个性化治疗与增强认知行为疗法和动态变化机制的试点研究
  • 批准号:
    10612256
  • 财政年份:
    2022
  • 资助金额:
    $ 19.56万
  • 项目类别:
A Pilot Randomized Control Trial of a Relapse Prevention Online Exposure Protocol for Eating Disorders and Mechanisms of Change
针对饮食失调和变化机制的复发预防在线暴露协议的试点随机对照试验
  • 批准号:
    10579874
  • 财政年份:
    2021
  • 资助金额:
    $ 19.56万
  • 项目类别:
A Pilot Randomized Control Trial of a Relapse Prevention Online Exposure Protocol for Eating Disorders and Mechanisms of Change
针对饮食失调和变化机制的复发预防在线暴露协议的试点随机对照试验
  • 批准号:
    10372099
  • 财政年份:
    2021
  • 资助金额:
    $ 19.56万
  • 项目类别:
A Pilot Investigation of Network-Informed Personalized Treatment for Eating Disorders versus Enhanced Cognitive Behavioral Therapy and Dynamic Mechanisms of Change
饮食失调的网络信息个性化治疗与增强认知行为疗法和动态变化机制的试点研究
  • 批准号:
    10542414
  • 财政年份:
    2021
  • 资助金额:
    $ 19.56万
  • 项目类别:
A Pilot Investigation of Network-Informed Personalized Treatment for Eating Disorders versus Enhanced Cognitive Behavioral Therapy and Dynamic Mechanisms of Change
饮食失调的网络信息个性化治疗与增强认知行为疗法和动态变化机制的试点研究
  • 批准号:
    10347759
  • 财政年份:
    2021
  • 资助金额:
    $ 19.56万
  • 项目类别:
Diversity Supplement for 'Personalized Networks and Sensor Technology Algorithms of Eating Disorder Symptoms Predicting Eating Disorder Outcomes'
“饮食失调症状的个性化网络和传感器技术算法预测饮食失调结果”的多样性补充
  • 批准号:
    10329150
  • 财政年份:
    2021
  • 资助金额:
    $ 19.56万
  • 项目类别:
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