TREAT (Time Restricted EATing) to improve cardiometabolic health

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Summary The Research Supplement to Promote Diversity in Health-Related Research to the parent grant 1R01AG065569-02A1 will provide support for the training of Dr Santos-Báez. The 2-year duration of the Research Supplement to Promote Diversity is driven by a number of factors including the necessary amount of required training in: 1) The ABC of clinical research (ethics, IRB applications, responsible conduct of research, rigor of data collection and data recording, establishing a manual of procedure); 2) Methods for assessment of energy balance and glucose metabolism used in the parent grant; 3) Critical review of literature pertinent to the project; 4) Principle of statistical analyses; 5) Scientific writing of abstracts, poster and manuscripts. The timing of this Supplement will coincide with year 3 and 4 of a 5-year parent R01 (end date 6/30/2025). The proposed Diversity Supplement will provide needed training in the design and execution of a clinical trial of time restricted eating in older adults with obesity and prediabetes. The career goal of Dr. Santos-Báez is to become an independent investigator conducting interdisciplinary research with a specific focus on becoming a leader in prevention of metabolic diseases in vulnerable populations. Ultimately, completion of this proposal will establish career launching trajectory in obesity and dysmetabolism. At the completion of the 2-year training, the candidate should be able to develop novel hypotheses, propose appropriate study design and methods to test these hypotheses, and write a K award application.