TREAT (Time Restricted EATing) to improve cardiometabolic health

TREAT（限时进食）可改善心脏代谢健康

• 批准号: 10614729
• 负责人: BLANDINE B LAFERRERE
• 金额: $ 13.32万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10614729
• 关键词: Clinical Research; Clinical Trials; Data; Data Collection; Elderly; Goals; Health; Institutional Review Boards; Interdisciplinary Study; K-Series Research Career Programs; Manuals; Manuscripts; Metabolic Diseases; Methods; Obesity; Parents; Prediabetes syndrome; Prevention; Procedures; Research; Research Design; Research Ethics; Research Personnel; Review Literature; Statistical Data Interpretation; Testing; Time-restricted feeding; Training; Training Support; Vulnerable Populations; Writing; adult obesity; cardiometabolism; career; design; energy balance; glucose metabolism; improved; novel; parent grant; posters; responsible research conduct

Summary The Research Supplement to Promote Diversity in Health-Related Research to the parent grant 1R01AG065569-02A1 will provide support for the training of Dr Santos-Báez. The 2-year duration of the Research Supplement to Promote Diversity is driven by a number of factors including the necessary amount of required training in: 1) The ABC of clinical research (ethics, IRB applications, responsible conduct of research, rigor of data collection and data recording, establishing a manual of procedure); 2) Methods for assessment of energy balance and glucose metabolism used in the parent grant; 3) Critical review of literature pertinent to the project; 4) Principle of statistical analyses; 5) Scientific writing of abstracts, poster and manuscripts. The timing of this Supplement will coincide with year 3 and 4 of a 5-year parent R01 (end date 6/30/2025). The proposed Diversity Supplement will provide needed training in the design and execution of a clinical trial of time restricted eating in older adults with obesity and prediabetes. The career goal of Dr. Santos-Báez is to become an independent investigator conducting interdisciplinary research with a specific focus on becoming a leader in prevention of metabolic diseases in vulnerable populations. Ultimately, completion of this proposal will establish career launching trajectory in obesity and dysmetabolism. At the completion of the 2-year training, the candidate should be able to develop novel hypotheses, propose appropriate study design and methods to test these hypotheses, and write a K award application.

总结 促进健康相关研究多样性的研究补助金 1 R 01 AG 065569 - 02 A1将为Santos-Báez博士的培训提供支持。2年 促进多样性的研究补充的持续时间由许多因素决定 包括以下方面的必要培训：1）临床研究的ABC（伦理学， IRB申请、负责任的研究行为、严格的数据收集和数据记录， 建立程序手册）; 2）能量平衡和血糖评估方法 代谢中使用的父母补助金; 3）与该项目有关的文献的批判性审查; 4） 统计分析原理; 5）论文摘要、海报和手稿的科学写作。的 该补充的时间将与5年期母公司R 01的第3年和第4年（结束日期）一致 2025年6月30日）。拟议的多样性补充将提供设计方面的必要培训， 在患有肥胖症和糖尿病前期的老年人中进行时间限制饮食的临床试验。 Santos-Báez博士的职业目标是成为一名独立的调查员， 跨学科研究，特别关注成为预防代谢性疾病的领导者 弱势群体的疾病。最终，完成这项提案将建立职业生涯 肥胖和代谢障碍的发展轨迹。在两年的培训结束后， 候选人应能够提出新的假设，提出适当的研究设计， 方法来测试这些假设，并写一个K奖的应用程序。