ADMINISTRATIVE CORE

拟议的癌症联盟的研究主题集中在卡波西肉瘤相关人类疱疹病毒和人乳头瘤病毒的分子流行病学，这两种病毒是坦桑尼亚最常见的两种与艾滋病相关的癌症(卡波西肉瘤和宫颈癌)的病原体。该联盟的目标是将内布拉斯加-林肯大学、内布拉斯加大学医学中心和海洋之路癌症研究所(ORCI)的关键专业知识和资源联系起来，在对该联盟的整体研究主题至关重要的三个领域发展ORCI研究基础设施：实验室、流行病学和临床护理。行政/协调核心将提供必要的行政和方案领导和基础设施，以确保联合体高效和有效地运作。行政/协调核心将追求三个具体目标：1)提供必要的行政专业知识和资源，以支持联盟的指导/职业发展核心、共享资源核心和研究项目实现其目标和具体目的；2)实施联盟范围内的一系列活动，旨在创造一个合作研究环境，并为联盟成员之间和其他同事之间的互动提供机会；以及3)提供有效的沟通，以告知和吸引合作伙伴、合作者以及政府或机构利益相关者，以促进联盟的本地和全球发展。行政/协调核心的组织旨在响应、包容和强大，这对于成功处理撒哈拉以南非洲艾滋病毒和癌症联盟计划内、合作和合作机构之间以及与美国国立卫生研究院之间的广泛使命和复杂关系至关重要。这一核心将侧重于满足伙伴关系和合作者在当前快速变化的科学和技术进步的环境中的需求，这将导致一个具有活力的研究项目的可持续联盟，这些项目致力于减少坦桑尼亚和整个撒哈拉以南非洲地区的艾滋病和非艾滋病恶性肿瘤。

The research theme of the proposed Cancer Consortium focuses around the molecular epidemiology of Kaposi's Sarcoma-associated Human Herpesvirus and Human Papilloma Virus, etiological agents of the two most prevalent AIDS-associated cancers in Tanzania (Kaposi's Sarcoma and cervical cancer).The Consortium's goal, which will link key expertise and resources at the University of Nebraska-Lincoln, University of Nebraska Medical Center, and Ocean Road Cancer Institute (ORCI), is to develop a ORCI research infrastructure in three areas critical to the Consortium's overall research theme: laboratory, epidemiology, and clinical care. An Administrative/Coordinating Core will provide the administrative and programmatic leadership and infrastructure necessary to ensure the Consortium functions efficiently and effectively. The Administrative/Coordinating Core will pursue three specific aims: 1) Provide the administrative expertise and resources necessary to support the Consortium's Mentoring/Career Development Core, Shared Resources Cores, and Research Projects in the accomplishment of their goals and specific aims; 2) Implement a Consortium-wide series of activities designed to create a collaborative research environment and provide opportunities for Consortium members to interact with one another and other colleagues; and 3) Provide effective communications to inform and engage the partnership, collaborators, and governmental or institutional stakeholders to promote the Consortium locally and globally. The organization of the Administrative/Coordinating Core is designed to be responsive, inclusive, and robust, which is essential to successfully address the broad mission and complex relationships within the Sub- Saharan African HIV and Cancer Consortium Program, among partnering and collaborating institutions, and with NIH. This core will focus on meeting the needs of the partnership and collaborators in the current climate, of rapidly changing scientific and technological advances, which will result in a sustainable Consortium with vibrant research programs that work toward the reduction of AIDS and non-AIDS malignancies in Tanzania and throughout sub-Saharan Africa.