NeuroHIV and Community Partnership and Disparity Core for Institution # 269291

NeuroHIV 和社区伙伴关系以及机构的差异核心

• 批准号: 10615184
• 负责人: Sarah B Bass
• 金额: $ 10.19万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-05 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615184
• 关键词: Address; Affect; Applications Grants; Awareness; Basic Science; Bioinformatics; Caring; Cellular biology; Clinical; Clinical Research; Communication; Communities; Complement; Consultations; Continuity of Patient Care; Development; Discipline; Disease; Disparity; Fostering; Friends; Goals; HIV; HIV diagnosis; HIV disparities; HIV/AIDS; Health Services; Impairment; Inequity; Infection; Infrastructure; Institution; Intervention; Knowledge; Manuscripts; Memory; Mental Depression; Mentors; Mentorship; Needs Assessment; Neurobehavioral Manifestations; Neurocognitive; Neurocognitive Deficit; Participant; Persons; Population; Positioning Attribute; Poverty; Prevention; Publications; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Risk; Science; Scientist; Services; Social Work; Time; Translating; Translational Research; Twitter; Underrepresented Minority; Underrepresented Populations; Universities; Viral; Viral Genes; Viremia; Work; antiretroviral therapy; care systems; community engaged research; community engagement; community organizations; community partnership; comorbidity; cultural competence; empowerment; ethnic minority population; executive function; experience; gender minority group; health disparity; health inequalities; innovation; interdisciplinary collaboration; marginalized population; member; minority investigator; neuroAIDS; neurobehavioral; patient population; prevent; racial minority population; recruit; service providers; sexual minority group; social determinants; social health determinants; social media; social stigma; structural determinants; symposium; synergism; treatment adherence; web page

SUMMARY Despite many people with HIV (PWH) having well-suppressed infection with antiretroviral treatment (ART), some populations of PWH experience disparities in their engagement in the HIV care continuum from timely HIV diagnosis to viral suppression. These disparities, particularly the delayed initiation of ART and disruptions to HIV care and ART adherence, may place populations deemed at risk or hard to reach at further risk of neuroHIV- related complications, including neurocognitive impairments and neurobehavioral sequelae as well as other comorbid clinical problems. Reducing HIV-related health disparities and health inequities is one of the four goals of the National HIV/AIDS Strategy. The Comprehensive NeuroHIV Center (CNHC) is well-positioned not only to support research that addresses the mechanisms of neuroHIV, but also how to facilitate exciting interdisciplinary collaborations to investigate, prevent, treat, and address disparities that may contribute significantly to neuroHIV- related disease in marginalized populations. By supporting a community-engaged research paradigm, the CNHC will maximize the impact of neuroHIV scientists’ research for populations affected by health disparities while leveraging community members’ expertise about their needs, strengths, and experiences. Thus, in this renewal, we have initiated the NeuroHIV Community Partnership and Disparities Core (NHCPDC) to foster community- partnership and interdisciplinary collaborations that examine, address, and prevent disparities involving neuroHIV. The NHCPDC will aim to (1) conduct a community needs assessment to refine the Core’s research infrastructure services; (2) serve as a primary resource to guide culturally competent research that engages communities and addresses neuroHIV disparities; and (3) disseminate research findings in bidirectional communication with the local and broader community to address neuroHIV disparities. The NHCPDC will work in synergy with the Central Administrative and Management Core to complement its support by aiding research involving neuroHIV disparities; the Developmental Research and Mentorship Core to support a diverse group of researchers and NHCPDC-related studies; and the Clinical and Translational Research Support Core to enhance its services for culturally competent research and expand its recruitment efforts involving underrepresented groups at greater risk of developing neuroHIV; and all Cores, including the Viral Gene Editing and Bioinformatics Core and the Cell Biology and Functional Analysis Core, to help disseminate findings and facilitate community awareness and involvement with respect to the development of neuroHIV. The Core will increase the number of interdisciplinary collaborations and resulting studies and publications. In synergy with the other Cores, the NHCPDC will enhance the quality of the neuroHIV research enterprise by supporting research related to neuroHIV disparities and the continuum of HIV care to prevent, treat, and understand neuroHIV disease in marginalized populations most at risk.

概括 尽管许多艾滋病毒（PWH）患有抗逆转录病毒治疗（ART）的感染良好的人，但有些 PWH的人群经历了及时的HIV参与艾滋病毒护理连续体的经验分布 诊断为病毒抑制。这些差异，特别是艺术和艾滋病毒中断的延迟倡议 护理和艺术依从性，可能会使被认为有风险或难以达到神经hiv的风险的人群 相关并发症，包括神经认知障碍和神经性后遗症以及其他并发症 合并临床问题。减少与HIV相关的健康差异和健康不平等是四个目标之一 国家艾滋病毒/艾滋病战略。综合神经hiv中心（CNHC）的位置很好，不仅是 支持研究神经hiv机制的研究，以及如何促进令人兴奋的跨学科 调查，预防，治疗和解决可能对Neurohiv-的分布的协作 边缘化人群中的相关疾病。通过支持社区参与的研究范例，CNHC 将最大程度地提高神经Hiv科学家对受健康差异影响的人群的影响 利用社区成员对他们的需求，优势和经验的专业知识。在这个续约中， 我们已经启动了Neurohiv社区的伙伴关系和差异核心（NHCPDC），以促进社区 - 伙伴关系和跨学科合作，检查，解决和防止涉及的差异 Neurohiv。 NHCPDC将旨在（1）进行社区需求评估以完善核心的研究 基础架构服务； （2）作为指导参与文化胜任的研究的主要资源 社区和解决神经hiv的差异； （3）在双向中传播研究结果 与当地和更广泛的社区进行沟通，以解决神经hiv的差异。 NHCPDC将起作用 与中央行政和管理核心协同作用，通过协助研究来完成其支持 涉及神经hiv的差异；发展研究和指导核心，以支持一组 研究人员和NHCPDC相关的研究；以及临床和转化研究支持核心以增强 它为具有文化胜任的研究的服务，并扩大其招聘工作涉及的人数不足 患神经hiv的风险更大的群体；以及所有核心，包括病毒基因编辑和生物信息学 核心和细胞生物学和功能分析核心，以帮助传播发现和寄主社区 关于神经hiv的发展的意识和参与。核心将增加 跨学科的合作以及由此产生的研究和出版物。与其他核心协同作用 NHCPDC将通过支持与 神经性差异和HIV护理的连续性，以预防，治疗和理解神经hiv病 边缘化的人口最有风险。