SWG2: End the HIV Epidemic

SWG2：结束艾滋病毒流行

• 批准号: 10615839
• 负责人: ANN K AVERY
• 金额: $ 4.44万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615839
• 关键词: AIDS clinical trial group; AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Advocacy; Affect; Applications Grants; Automobile Driving; Award; Behavioral Research; Biomedical Research; Black race; Clinical; Clinical Trials Unit; Collaborations; Communities; Community Health; County; Data; Development; Diagnosis; Dimensions; Education; Epidemic; Event; Fostering; Funding; Gender; Geographic Locations; Geography; Goals; Grant; Growth; HIV; HIV Infections; HIV Vaccine Trials Network; HIV/AIDS; Health; Hour; Incidence; Institution; Interdisciplinary Study; Intervention; Investments; Joints; Leadership; Link; Medicine; Mentorship; Mission; Policies; Policy Maker; Population; Prevention; Prevention Research; Privatization; Process; Productivity; Public Health; Recording of previous events; Research; Research Infrastructure; Research Personnel; Research Priority; Research Project Grants; Research Proposals; Research Training; Resources; Science; Site; Structure; Training; Underrepresented Minority; United States; United States Dept. of Health and Human Services; United States Health Resources and Services Administration; United States National Institutes of Health; Universities; biobehavior; community based participatory research; community engagement; demographics; design; empowerment; implementation research; implementation science; inter-institutional; interdisciplinary collaboration; investigator training; meetings; member; neighborhood disadvantage; population based; pre-exposure prophylaxis; prevent; programs; response; sex; sexual minority community; sexual minority men; shared decision making; social; success; working group

PROJECT SUMMARY/ABSTRACT: ENDING THE HIV EPIDEMIC SCIENTIFIC WORKING GROUP 2 The U.S. Department of Health and Human Services (HHS) has proposed to end the HIV epidemic in the United States with the ambitious goal of 75% reduction in new HIV infections in 5 years and 90% reduction in 10 years targeting communities hardest hit by the epidemic. Cuyahoga County, where Case Western Reserve University (CWRU) is located, is one of the 48 highest burden counties. CWRU and University of Pittsburgh (Pitt) will create an Ending the HIV Epidemic (EHE) Scientific Working Group (SWG2) within the RUSTBELT CFAR. The overarching goal of the EHE SWG2 is to promote interdisciplinary collaborations that result in successful applications for new HIV prevention and implementation research projects. Pitt has a diverse portfolio of successful biomedical and behavioral research with active community engagement including initiatives such as AIDS-Free Pittsburgh. Recently, Allegheny County has significantly reduced its HIV incidence from 139 cases in 2015 to 85 cases in 2018. CWRU has a strong relationship with local public health officials and the HIV community, in which formal and informal channels have been maintained for over 19 years with deep roots to community inclusion via public and private organizations and numerous community events and educational meetings. EHE SWG2 will build on the regional, cultural, and demographic similarities between Pittsburgh and Cleveland to promote robust HIV prevention research, practice, and research training. The EHE SWG2 has two aims: (1) Expand academic/community/practitioner partnerships to develop research programs that identify gaps across EHE pillars in Cleveland and Pittsburgh. EHE SWG2 will bring together researchers, community stakeholders, and nontraditional partners to address each of the pillars of the National Plan to End the HIV Epidemic. SWG leadership will provide support to investigators to implement an array of successful community- based HIV prevention and implementation research programs. This initiative will produce joint Pitt/CWRU investigative teams and generate valuable pilot data for additional End the HIV Epidemic supplementary proposals and other R21/R34 mechanisms. (2) Facilitate new EHE implementation research projects that align with the pillars of the NIH HIV strategy in communities disproportionately impacted by HIV. EHE SWG2 will develop productive interactions with RUSTBELT CFAR Cores, Sex & Gender SWG1, and the Inter-CFAR Implementation Science Working Group to develop grant proposals for a robust EHE research and practice, leveraging each institution’s strengths to facilitate a new, dynamic program of HIV prevention implementation and research. The EHE SWG2 will utilize an empowered community framework for shared decision-making in EHE research prioritization, design, implementation, and dissemination and support the development of new research initiatives and advocacy for local- and state-level policy changes. By focusing its resources on communities most affected by HIV and developing an effective HIV prevention research infrastructure, the EHE SWG2 represents a key first step on the path to ending the HIV epidemic in the rustbelt region.

项目摘要/摘要：结束艾滋病毒流行科学工作组2 美国卫生与公众服务部(HHS)已提议结束艾滋病在美国的流行 美国雄心勃勃的目标是在5年内减少75%的新艾滋病毒感染，在10年内减少90% 几年来，目标是受疫情影响最严重的社区。凯霍加县，凯斯西部保护区 大学(CWRU)所在的县是48个负担最重的县之一。CWRU和匹兹堡大学(匹兹堡) 将在锈带CFAR内创建一个结束艾滋病毒流行(EHE)科学工作组(SWG2)。 EHE SWG2的首要目标是促进跨学科协作，从而取得成功 申请新的艾滋病毒预防和实施研究项目。皮特拥有不同的投资组合 通过积极的社区参与成功的生物医学和行为研究，包括以下倡议 没有艾滋病的匹兹堡。最近，阿勒格尼县的艾滋病毒发病率从139例大幅下降 从2015年的85起增加到2018年的85起。CWRU与当地公共卫生官员和艾滋病毒 社区，在这个社区中，正式和非正式的渠道已经保持了19年以上，并具有深厚的 通过公共和私人组织以及众多社区活动和教育实现社区包容 开会。EHE SWG2将建立在匹兹堡和匹兹堡之间的区域、文化和人口结构相似性的基础上 克利夫兰促进强有力的艾滋病毒预防研究、实践和研究培训。EHE SWG2有两个 目标：(1)扩大学术/社区/实践者伙伴关系，以制定找出差距的研究计划 横跨克利夫兰和匹兹堡的柱子。EHE SWG2将把研究人员、社区聚集在一起 利益攸关方和非传统合作伙伴处理结束艾滋病毒国家计划的每一个支柱 流行病。SWG领导层将为调查人员提供支持，以实施一系列成功的社区- 以艾滋病毒预防和实施研究方案为基础。这项倡议将产生PIT/CWRU联合 调查小组并为进一步结束艾滋病毒流行补充提供有价值的试点数据 提案和其他R21/R34机制。(2)促进符合以下条件的新的EHE实施研究项目 以美国国立卫生研究院艾滋病毒战略的支柱为基础，在受艾滋病毒影响不成比例的社区开展这项工作。EHE SWG2将 与锈带CFAR核心、性别和性别SWG1以及内部CFAR发展富有成效的互动 实施科学工作组，为健全的环境和环境卫生研究和实践制定赠款建议， 利用每个机构的优势促进新的、充满活力的艾滋病毒预防计划的实施 和研究。EHE SWG2将利用授权的社区框架在 EHE研究的优先顺序、设计、实施和传播，并支持开发新的 研究倡议和倡导地方和州一级的政策变化。通过将其资源集中在 受艾滋病毒影响最严重的社区，并开发有效的艾滋病毒预防研究基础设施，EHE SWG2是在铁锈带地区结束艾滋病毒流行的道路上迈出的关键的第一步。