SWG2: End the HIV Epidemic

SWG2：结束艾滋病毒流行

• 批准号: 10615839
• 负责人: ANN K AVERY
• 金额: $ 4.44万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615839
• 关键词: AIDS clinical trial group; AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Advocacy; Affect; Applications Grants; Automobile Driving; Award; Behavioral Research; Biomedical Research; Black race; Clinical; Clinical Trials Unit; Collaborations; Communities; Community Health; County; Data; Development; Diagnosis; Dimensions; Education; Epidemic; Event; Fostering; Funding; Gender; Geographic Locations; Geography; Goals; Grant; Growth; HIV; HIV Infections; HIV Vaccine Trials Network; HIV/AIDS; Health; Hour; Incidence; Institution; Interdisciplinary Study; Intervention; Investments; Joints; Leadership; Link; Medicine; Mentorship; Mission; Policies; Policy Maker; Population; Prevention; Prevention Research; Privatization; Process; Productivity; Public Health; Recording of previous events; Research; Research Infrastructure; Research Personnel; Research Priority; Research Project Grants; Research Proposals; Research Training; Resources; Science; Site; Structure; Training; Underrepresented Minority; United States; United States Dept. of Health and Human Services; United States Health Resources and Services Administration; United States National Institutes of Health; Universities; biobehavior; community based participatory research; community engagement; demographics; design; empowerment; implementation research; implementation science; inter-institutional; interdisciplinary collaboration; investigator training; meetings; member; neighborhood disadvantage; population based; pre-exposure prophylaxis; prevent; programs; response; sex; sexual minority community; sexual minority men; shared decision making; social; success; working group

PROJECT SUMMARY/ABSTRACT: ENDING THE HIV EPIDEMIC SCIENTIFIC WORKING GROUP 2 The U.S. Department of Health and Human Services (HHS) has proposed to end the HIV epidemic in the United States with the ambitious goal of 75% reduction in new HIV infections in 5 years and 90% reduction in 10 years targeting communities hardest hit by the epidemic. Cuyahoga County, where Case Western Reserve University (CWRU) is located, is one of the 48 highest burden counties. CWRU and University of Pittsburgh (Pitt) will create an Ending the HIV Epidemic (EHE) Scientific Working Group (SWG2) within the RUSTBELT CFAR. The overarching goal of the EHE SWG2 is to promote interdisciplinary collaborations that result in successful applications for new HIV prevention and implementation research projects. Pitt has a diverse portfolio of successful biomedical and behavioral research with active community engagement including initiatives such as AIDS-Free Pittsburgh. Recently, Allegheny County has significantly reduced its HIV incidence from 139 cases in 2015 to 85 cases in 2018. CWRU has a strong relationship with local public health officials and the HIV community, in which formal and informal channels have been maintained for over 19 years with deep roots to community inclusion via public and private organizations and numerous community events and educational meetings. EHE SWG2 will build on the regional, cultural, and demographic similarities between Pittsburgh and Cleveland to promote robust HIV prevention research, practice, and research training. The EHE SWG2 has two aims: (1) Expand academic/community/practitioner partnerships to develop research programs that identify gaps across EHE pillars in Cleveland and Pittsburgh. EHE SWG2 will bring together researchers, community stakeholders, and nontraditional partners to address each of the pillars of the National Plan to End the HIV Epidemic. SWG leadership will provide support to investigators to implement an array of successful community- based HIV prevention and implementation research programs. This initiative will produce joint Pitt/CWRU investigative teams and generate valuable pilot data for additional End the HIV Epidemic supplementary proposals and other R21/R34 mechanisms. (2) Facilitate new EHE implementation research projects that align with the pillars of the NIH HIV strategy in communities disproportionately impacted by HIV. EHE SWG2 will develop productive interactions with RUSTBELT CFAR Cores, Sex & Gender SWG1, and the Inter-CFAR Implementation Science Working Group to develop grant proposals for a robust EHE research and practice, leveraging each institution’s strengths to facilitate a new, dynamic program of HIV prevention implementation and research. The EHE SWG2 will utilize an empowered community framework for shared decision-making in EHE research prioritization, design, implementation, and dissemination and support the development of new research initiatives and advocacy for local- and state-level policy changes. By focusing its resources on communities most affected by HIV and developing an effective HIV prevention research infrastructure, the EHE SWG2 represents a key first step on the path to ending the HIV epidemic in the rustbelt region.

项目概要/摘要：结束艾滋病毒流行病学科学工作组2 美国卫生与公众服务部（HHS）建议结束艾滋病毒在美国的流行。 美国的雄心勃勃的目标是在5年内减少75%的新艾滋病毒感染，在10年内减少90% 多年来针对受疫情影响最严重的社区。凯霍加县凯斯西储 大学（CWRU）所在地，是48个负担最高的县之一。CWRU和匹兹堡大学（皮特） 将在RUSTBELT CFAR内建立一个终止艾滋病毒流行（EHE）科学工作组（SWG 2）。 EHE SWG 2的总体目标是促进跨学科合作，从而成功地 申请新的艾滋病毒预防和实施研究项目。皮特有一个多样化的投资组合， 成功的生物医学和行为研究与积极的社区参与，包括倡议， 无艾滋病匹兹堡最近，阿勒格尼县的艾滋病发病率从139例大幅下降， 从2015年的85例增加到2018年的85例。CWRU与当地公共卫生官员和艾滋病毒感染者有着密切的关系。 社区，其中正式和非正式渠道已保持了19年以上，具有深厚的根基， 通过公共和私营组织以及众多社区活动和教育活动， 会议. EHE SWG 2将建立在匹兹堡和 克利夫兰促进强有力的艾滋病毒预防研究，实践和研究培训。EHE SWG 2有两个 目标：（1）扩大学术界/社区/从业者的伙伴关系，以制定找出差距的研究计划 在克利夫兰和匹兹堡的EHE支柱之间。EHE SWG 2将汇集研究人员，社区 利益攸关方和非传统合作伙伴，以解决国家消除艾滋病毒计划的每一个支柱， 疫情SWG领导层将为调查人员提供支持，以实施一系列成功的社区- 艾滋病预防和实施研究项目。这一举措将产生联合皮特/CWRU 调查小组，并产生宝贵的试点数据，以增加终止艾滋病毒流行的补充 建议和其他R21/R34机制。(2)促进新的EHE实施研究项目， 在受艾滋病毒影响不成比例的社区，与NIH艾滋病毒战略的支柱合作。EHE SWG 2将 与RUSTBELT CFAR核心、性与性别SWG 1和Inter-CFAR发展富有成效的互动 实施科学工作组，为强大的EHE研究和实践制定赠款提案， 利用每个机构的优势，促进新的、有活力的艾滋病毒预防方案的实施 与研究EHE SWG 2将利用授权的社区框架进行共享决策， EHE研究优先级，设计，实施和传播，并支持新的开发 研究倡议和倡导地方和州一级的政策变革。通过集中资源 艾滋病毒影响最严重的社区，并建立有效的艾滋病毒预防研究基础设施，EHE SWG 2代表了在锈带地区结束艾滋病毒流行的道路上迈出的关键的第一步。