The UConn/JAX-GM Training Program in Genomic Science

项目概要 我们建议建立 UConn/JAX-GM 基因组科学培训计划来培训 下一代基因组科学家。该计划利用了独特的组合 康涅狄格大学健康中心 (UConn Health）和位于康涅狄格州法明顿的杰克逊基因组医学实验室（JAX-GM）。一起 康涅狄格大学和 JAX-GM 已经超过了基因组科学专业教师的临界数量 将康涅狄格州法明顿打造成美国领先的基因组研究卓越中心之一 世界。例如，我们的研究人员包括 ENCODE、1000 Genomes、TCGA、 4D 核组和微生物组联盟项目。 JAX 和 UConn 也都有出色的表现 卓越的培训历史。我们的机构提供出色的设施来执行 基因组研究包括优秀的计算资源、轻松访问每个 DNA 和 RNA测序平台、干细胞和基因组工程核心设施以及联合实验室 UConn/JAX-GM 单细胞基因组学设施。我们建议利用我们的专业知识并真正 独特的培训环境，用于教育和指导现代基因组学博士前学员 科学。该培训将包括教学课程、研讨会系列、技术实践 研讨会以及参加基因组学国际会议。学员将接触到 湿式和干式基因组研究，并且能够生成和分析基因组数据。 学员将在系统的基础生物学方面打下坚实的基础 研究以及正确解释数据所需的计算和统计方法。 学员还将接受有关道德科学行为的教育。

PROJECT SUMMARY We propose to establish the UConn/JAX-GM Training Program in Genomic Sciences to train the next generation of genomic Scientists. This program leverages the unique combination of a recent, but thriving relationship between the University of Connecticut Health Center (UConn Health) and Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT. Together UConn and JAX-GM have exceeded the critical mass of faculty specializing in genomic sciences to establish Farmington, CT as one of the leading hubs of excellence in genomic research in the world. For example, our research faculty include leaders of the ENCODE, 1000 Genomes, TCGA, 4D Nucleome, and Microbiome consortium projects. Both JAX and UConn also have outstanding histories of excellence in training. Our institutions provide outstanding facilities to perform genomic research including excellent computational resources, easy access to every DNA and RNA sequencing platform, a stem cell and genome engineering core facility, and a joint UConn/JAX-GM single cell genomics facility. We propose to leverage our expertise and truly unique training environment to educate and mentor pre-doctoral trainees in modern genomic sciences. This training will include didactic courses, seminar series, hands on technical workshops, and attending international conferences in genomics. Trainees will be exposed to both wet and dry genomic research and will be able to both generate and analyze genomic data. Trainees will be given a strong foundation in both the underlying biology of the systems being studied and the computational and statistical methods required to correctly interpret data. Trainees will also be educated about ethical scientific behavior.