The UConn/JAX-GM Training Program in Genomic Science

项目摘要 我们建议建立康州大学/JAX-GM基因组科学培训计划， 下一代基因组科学家该计划利用了独特的组合， 最近，但蓬勃发展的关系之间的康涅狄格大学健康中心（UConn 健康）和杰克逊基因组医学实验室（JAX-GM）在法明顿，CT。一起 康州大学和JAX-GM已经超过了专门从事基因组科学的教师的临界质量 建立法明顿，CT作为卓越的基因组研究的领先枢纽之一， 世界例如，我们的研究人员包括ENCODE，1000个基因组，TCGA， 4D Nucleome和Microbiome联盟项目。JAX和UConn都有出色的 优秀的训练历史。我们的院校提供卓越的设施， 基因组研究，包括优秀的计算资源，容易获得每一个DNA， RNA测序平台，干细胞和基因组工程核心设施，以及联合 UConn/JAX-GM单细胞基因组学设施。我们建议利用我们的专业知识， 独特的培训环境，以教育和指导现代基因组学的博士前学员 以理工科为重该培训将包括教学课程，研讨会系列，动手技术 研讨会以及参加基因组学国际会议。学员将接触到 无论是湿的还是干的基因组研究，都将能够生成和分析基因组数据。 学员将获得一个坚实的基础，在这两个系统的基础生物学， 研究以及正确解释数据所需的计算和统计方法。 学员还将接受有关伦理科学行为的教育。

PROJECT SUMMARY We propose to establish the UConn/JAX-GM Training Program in Genomic Sciences to train the next generation of genomic Scientists. This program leverages the unique combination of a recent, but thriving relationship between the University of Connecticut Health Center (UConn Health) and Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT. Together UConn and JAX-GM have exceeded the critical mass of faculty specializing in genomic sciences to establish Farmington, CT as one of the leading hubs of excellence in genomic research in the world. For example, our research faculty include leaders of the ENCODE, 1000 Genomes, TCGA, 4D Nucleome, and Microbiome consortium projects. Both JAX and UConn also have outstanding histories of excellence in training. Our institutions provide outstanding facilities to perform genomic research including excellent computational resources, easy access to every DNA and RNA sequencing platform, a stem cell and genome engineering core facility, and a joint UConn/JAX-GM single cell genomics facility. We propose to leverage our expertise and truly unique training environment to educate and mentor pre-doctoral trainees in modern genomic sciences. This training will include didactic courses, seminar series, hands on technical workshops, and attending international conferences in genomics. Trainees will be exposed to both wet and dry genomic research and will be able to both generate and analyze genomic data. Trainees will be given a strong foundation in both the underlying biology of the systems being studied and the computational and statistical methods required to correctly interpret data. Trainees will also be educated about ethical scientific behavior.