Brain networks for specific motor control impairments following stroke
中风后特定运动控制障碍的大脑网络
基本信息
- 批准号:10620400
- 负责人:
- 金额:$ 6.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-08-01 至 2025-07-31
- 项目状态:未结题
- 来源:
- 关键词:Alaska NativeAmerican IndiansAwardBase of the BrainBiomechanicsBrainClinicalCommunicationDataDevelopmentDoctor of PhilosophyElectroencephalographyEngineeringFeedbackFemaleFosteringHandImpairmentIndividualKnowledgeMotorMotor CortexPhaseProcessRehabilitation OutcomeRehabilitation therapyReportingResearchResearch PersonnelScientistSensoryStrokeTraining ActivityUnderrepresented MinorityUpper Extremitycareerdesigngrasphand dysfunctionhand rehabilitationimprovedinnovationinsightmalemotor controlmotor impairmentneurological rehabilitationneuromechanismparent grantpersonalized medicinepost strokeprogramsrehabilitation paradigmrehabilitation researchrelating to nervous systemskillsstroke survivor
项目摘要
PROJECT SUMMARY / ABSTRACT
The objective of the parent grant (R01 HD094731) is to determine if combining TheraBracelet with hand task
practice is superior to hand task practice alone for recovery of hand function post-stroke in an adequately
powered study. The parent grant Aim 2 focuses on determining the effect of TheraBracelet on sensorimotor grip
control and neural communication within the cortical sensorimotor network. This diversity supplement will provide
a new insight into the neural mechanisms for different grip control impairments among individual stroke survivors.
Specifically, the aim of this diversity supplement is to determine the brain network responsible for the feedforward
and feedback motor control in stroke survivors. It is hypothesized that feedforward motor control will be
associated with connectivity within the motor cortices during the motor planning phase, while feedback motor
control will be associated with connectivity between the sensory and motor regions during the motor execution
phase. This research is expected to unveil the specific brain network responsible for the feedforward and
feedback motor control of the upper extremity. Innovation is in investigating brain networks and motor controls
together. This new knowledge will be critical for the development of a personalized post-stroke rehabilitation
paradigm: This paradigm may involve first assessing individual motor control processes to determine the specific
motor control that is responsible for clinical motor impairment, followed by design of a personalized treatment to
target the specific brain network responsible for the impaired motor control. Most importantly, this award will
foster the underrepresented minority candidate (Mr. Adam Baker) as a career DPT/PhD researcher. The training
activities will focus on developing new research skills for Mr. Baker to perform the supplement research and
begin his research career. Specifically, Mr. Baker will (1) enhance the overall knowledge of the
neurorehabilitation research field, (2) acquire proficiency in quantifying, analyzing, and interpreting feedforward
and feedback motor control biomechanics data and EEG-based brain network data, and (3) develop a successful
application for a DPT/PhD program. Therefore, this supplement award will contribute to enhancing diversity in
the biomedical workforce, as only 2,000 females are American Indian or Alaskan Native out of 1.76 million
employed scientists and engineers holding doctorates according to NSF report (data suppressed for males due
to reliability).
项目摘要/摘要
家长资助(R01 HD094731)的目标是确定是否将TheraBraclet与手工作业相结合
对于中风后手功能的充分恢复,练习优于单纯的手作业练习
动力研究。家长资助目标2侧重于确定TheraBraclet对感觉运动握力的影响
大脑皮层感觉运动网络内的控制和神经通讯。这一多样性补充将提供
对中风幸存者不同握力控制障碍的神经机制的新见解。
具体地说,这种多样性补充的目的是确定负责前馈的大脑网络
中风幸存者的反馈运动控制。据推测,前馈电机控制将是
在运动规划阶段与运动皮质内的连通性相关联,同时反馈运动
在运动执行过程中,控制将与感觉和运动区之间的连通性有关
相位。这项研究有望揭示负责前馈和前馈的特定大脑网络
上肢的反馈运动控制。创新在于研究大脑网络和运动控制
在一起。这一新知识将对个性化中风后康复的发展至关重要
范式:该范式可能包括首先评估单个运动控制过程,以确定具体的
负责临床运动障碍的运动控制,随后设计了个性化治疗
以负责运动控制受损的特定大脑网络为目标。最重要的是,这个奖项将
培养代表不足的少数族裔候选人(Adam Baker先生)成为职业DPT/博士研究员。培训
活动将集中于为贝克先生开发新的研究技能,以执行补充研究和
开始了他的研究生涯。具体地说,贝克先生将(1)提高对
神经康复研究领域,(2)精通量化、分析和解释前馈
并反馈运动控制生物力学数据和基于脑电信号的脑网络数据,以及(3)研制成功
申请DPT/PHD课程。因此,这项补充奖将有助于增强
生物医学劳动力,176万名女性中只有2000名是美国印第安人或阿拉斯加原住民
根据美国国家科学基金会的报告,拥有博士学位的受雇科学家和工程师(男性数据因
到可靠性)。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Na Jin Seo其他文献
Na Jin Seo的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Na Jin Seo', 18)}}的其他基金
EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
肌电图控制的游戏可重新训练中风后上肢肌肉激活模式
- 批准号:
10635090 - 财政年份:2023
- 资助金额:
$ 6.1万 - 项目类别:
Feasibility of Using Maestro Hand Exoskeleton in Post-stroke Hand Rehabilitation to Improve Joint Coordination
使用 Maestro 手部外骨骼进行中风后手部康复以提高关节协调性的可行性
- 批准号:
10515326 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Feasibility of Using Maestro Hand Exoskeleton in Post-stroke Hand Rehabilitation to Improve Joint Coordination
使用 Maestro 手部外骨骼进行中风后手部康复以提高关节协调性的可行性
- 批准号:
10368417 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Concomitant sensory stimulation during therapy to enhance hand functional recovery post stroke
治疗期间伴随感觉刺激以增强中风后手部功能恢复
- 批准号:
10677809 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
Impact of sensorimotor pathway integrity on hand motor recovery in stroke survivors
感觉运动通路完整性对中风幸存者手部运动恢复的影响
- 批准号:
10621421 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
Concomitant sensory stimulation during therapy to enhance hand functional recovery post stroke
治疗期间伴随感觉刺激以增强中风后手部功能恢复
- 批准号:
10170391 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
Effect of home task-practice compliance in real-world hand use in stroke survivors
家庭任务实践依从性对中风幸存者现实世界手部使用的影响
- 批准号:
10841181 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
Concomitant sensory stimulation during therapy to enhance hand functional recovery post stroke
治疗期间伴随感觉刺激以增强中风后手部功能恢复
- 批准号:
9884892 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
Concomitant sensory stimulation during therapy to enhance hand functional recovery post stroke
治疗期间伴随感觉刺激以增强中风后手部功能恢复
- 批准号:
10728386 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
Concomitant sensory stimulation during therapy to enhance hand functional recovery post stroke
治疗期间伴随感觉刺激以增强中风后手部功能恢复
- 批准号:
10728384 - 财政年份:2020
- 资助金额:
$ 6.1万 - 项目类别:
相似海外基金
Communication in American Indians thru Strategies for Equity 4 Cancer (CASE4Cancer)
美国印第安人通过公平策略进行沟通 4 癌症 (CASE4Cancer)
- 批准号:
10892489 - 财政年份:2023
- 资助金额:
$ 6.1万 - 项目类别:
Digital smoking cessation intervention for nationally-recruited American Indians and Alaska Natives: A full-scale randomized controlled trial
针对全国招募的美洲印第安人和阿拉斯加原住民的数字戒烟干预:一项全面的随机对照试验
- 批准号:
10826067 - 财政年份:2023
- 资助金额:
$ 6.1万 - 项目类别:
Medication Adherence and Cardio-Metabolic Control Indicators among Adult American Indians Receiving Tribal Health Services
接受部落卫生服务的成年美洲印第安人的药物依从性和心脏代谢控制指标
- 批准号:
10419967 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Examination of evolving opioid misuse and overdose risk among American Indians
检查美洲印第安人中不断变化的阿片类药物滥用和过量风险
- 批准号:
10438466 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Examination of evolving opioid misuse and overdose risk among American Indians
检查美洲印第安人中不断变化的阿片类药物滥用和过量风险
- 批准号:
10701719 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Culturally Responsive Palliative Care Messaging for American Indians: An Efficacy Trial
针对美洲印第安人的文化响应姑息治疗信息:功效试验
- 批准号:
10431092 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Culturally Responsive Palliative Care Messaging for American Indians: An Efficacy Trial
针对美洲印第安人的文化响应姑息治疗信息:功效试验
- 批准号:
10709495 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Advancing Palliative Care in Northern Plains American Indians
推进北部平原美洲印第安人的姑息治疗
- 批准号:
10705232 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Long-term consequences of SARS-CoV-2 infection and COVID-19 disease among American Indians: an ambidirectional cohort study in the Cherokee Nation
美洲印第安人中 SARS-CoV-2 感染和 COVID-19 疾病的长期后果:切罗基族的双向队列研究
- 批准号:
10438443 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别:
Advancing Palliative Care in Northern Plains American Indians
推进北部平原美洲印第安人的姑息治疗
- 批准号:
10643600 - 财政年份:2022
- 资助金额:
$ 6.1万 - 项目类别: