The Neuroimmunology Training Program at the University of Utah

犹他大学神经免疫学培训项目

• 批准号: 10621297
• 负责人: Ryan M O'Connell
• 金额: $ 23.33万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10621297
• 关键词: Training Programs; Universities; Utah; neuroimmunology

Neuroimmunology is a rapidly growing field of research that touches a number of critical human diseases including multiple sclerosis, epilepsy, spinal cord injury, and viral encephalopathies. Traditionally, researchers have been trained in either neuroscience or immunology whereas the Neuroimmunology Training Program at the University of Utah seeks to develop and train the next generation of researchers in both fields with a cross- disciplinary approach focused on the interplay between the immune and nervous systems during disease. This application is the result of ongoing collaborations between high caliber faculty on campus who recognized the need to develop a training program specific to the challenges of neuroimmunology. This application requests support for 4 pre-doctoral trainees who will be selected from an outstanding pool of candidates within our relevant graduate programs. The Neuroimmunology Training Program at the University of Utah will formally bring together 17 faculty members from across the neuroimmunology research spectrum to participate in mentorship, program-wide meetings, workshops, and boot camps to share expertise and further develop the neuroimmunology field. The training program will be overseen by two faculty directors and a steering committee focused on selecting and supporting trainees who are highly likely to exhibit continued success within the diverse field of neuroimmunology research. Selected trainees will be expected to participate in specialized training in quantitative literacy, statistical analysis, and scientific rigor and reproducibility within the context of neuroimmunology research. Given the exceptional training track record of our faculty, available and unique resources to support research and robust institutional support, the Neuroimmunology Training Program will provide and outstanding opportunity for trainees to develop intellectually, advance and optimize their thesis research projects, create a valuable network of colleagues, and prepare for a highly successful research career focused on the crossroads of immunology and neuroscience.

神经免疫学是一个快速发展的研究领域，涉及许多严重的人类疾病，包括多发性硬化症、癫痫、脊髓损伤和病毒性脑病。传统上，研究人员要么接受神经科学培训，要么接受免疫学培训，而犹他大学的神经免疫学培训计划旨在培养和培训这两个领域的下一代研究人员，采用跨学科的方法，重点研究疾病期间免疫系统和神经系统之间的相互作用。这个应用程序是校园内高素质教师之间持续合作的结果，他们认识到需要开发一个针对神经免疫学挑战的培训计划。本申请要求支持4名博士预科学员，他们将从我们相关研究生项目的优秀候选人中选出。犹他大学的神经免疫学培训项目将正式汇集来自神经免疫学研究领域的17名教职员工，参加指导、项目范围的会议、研讨会和新兵训练营，分享专业知识，进一步发展神经免疫学领域。培训计划将由两名教授主任和一个指导委员会监督，重点是选择和支持在神经免疫学研究的各个领域极有可能取得持续成功的学员。被选中的受训者将在神经免疫学研究的背景下参加定量素养、统计分析、科学严谨性和可重复性方面的专门培训。鉴于我们教师的卓越培训记录，可用的和独特的资源来支持研究和强大的机构支持，神经免疫学培训计划将为学员提供一个优秀的机会来发展智力，推进和优化他们的论文研究项目，创建一个有价值的同事网络，并为一个非常成功的研究生涯做好准备，专注于免疫学和神经科学的交叉。

项目成果

MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation.

MicroRNA-155 在神经炎症期间的脑浸润免疫细胞群中发挥选择性细胞内在作用。

• DOI: 10.4049/jimmunol.2200478
• 发表时间: 2023
• 期刊: Journal of immunology (Baltimore, Md. : 1950)
• 作者: Thompson,JacobW;Hu,Ruozhen;Huffaker,ThomasB;Ramstead,AndrewG;Ekiz,HAtakan;Bauer,KaylynM;Tang,WilliamW;Ghazaryan,Arevik;Round,JuneL;Fujinami,RobertS;O'Connell,RyanM
• 通讯作者: O'Connell,RyanM