Multidisciplinary Research Training in Gastroenterology and Hepatology

项目摘要 人类基因组测序的成功和人类健康服务研究的发展 后基因组时代为改变消化系统疾病的患者护理提供了前所未有的机会。 在过去的十年中，威尔康奈尔医学（WCM）在生物医学研究方面进行了重大投资， 以及研究培训和基础设施。这是一个来自WCM的新应用程序，它请求支持 在多学科研究培训中对四名临床和非临床博士后进行研究培训 胃肠病学和肝病学的MRTP计划，WCM为额外的培训提供资金 时隙目标是招募在基础科学方面有坚实基础的优秀候选人，并培养他们 运用他们的知识和技能，解决预防方面临床上未得到满足的重要需求， 消化系统疾病的诊断和治疗。MRTP学员将获得以下项目支持： 两年期间，他们将遵循一个结构化和严格的博士后培训计划。MRTP将 是来自WCM，纪念斯隆凯特琳癌症中心（MSKCC）和 洛克菲勒大学（RU），构成了一个密集的合作研究人员网络，他们是 胃肠病学和肝病学领域的国际领导者。这些导师有 已被组织成3个主题单位的研究培训：胃肠道恶性肿瘤，肝脏疾病和 以及粘膜免疫学和炎症。这些培训单位将促进发展 具体内容的教育规划，以及提高效率的培训管理 程序.监督将由一个研究培训执行委员会提供， 主任和2名副项目主任，他们也将担任培训单位的领导，以及2名 其他成员将提供有关临床/流行病学研究和实现 保持培训计划的多样性。我们还收集了一份优秀的内部名册， 和外部顾问委员会成员，负责评估该计划并提供具体的 建议提高其质量和效率。MRTP高度个性化的培训计划 将包括1）个人发展计划; 2）严格的研究培训; 3）切割实践经验- 边缘教学法; 4）综合课程。学员将进一步受益于广泛的 WCM、MSKCC和RU的机构资源。基于对我们奖学金项目兴趣的增长， 我们预计将有大量高素质的临床和非临床候选人参加拟议的MRTP， 这将保持一个强大的多样性重点。通过其严谨、结构化和高度个性化的 课程，这个新的培训计划旨在培养未来的领导人在消化系统疾病的研究谁是 准备将他们的发现转化为改善美国的病人护理。

PROJECT SUMMARY The successful sequencing of the human genome and the evolution of human health services research in the post-genomic era have offered unprecedented opportunities to transform patient care in digestive diseases. Over the past decade, Weill Cornell Medicine (WCM) has made major investments in biomedical research, as well as research training and infrastructure. This is a new application from WCM that requests support for the research training of four clinical and non-clinical postdoctoral fellows in a multidisciplinary research training program (MRTP) in Gastroenterology and Hepatology, with WCM providing funding for an additional training slot. The objective is to recruit outstanding candidates with solid foundations in basic science and train them to apply their knowledge and skills towards addressing important clinically unmet needs in the prevention, diagnosis, and treatment of patients with digestive diseases. MRTP trainees will receive program support for two years during which they will follow a structured and rigorous postdoctoral training program. The MRTP will be a joint effort of 28 eminent preceptors from WCM, Memorial Sloan Kettering Cancer Center (MSKCC) and the Rockefeller University (RU), which constitute a dense network of collaborative researchers, who are international leaders in fields directly relevant to gastroenterology and hepatology. These preceptors have been organized into 3 themed units of research training: gastrointestinal malignancies, liver diseases and regeneration, and mucosal immunology and inflammation. These training units will enable the development of content-specific educational programming, as well as increase the efficiency administration within the training program. Oversight will be provided by a Research Training Executive Committee consisting of the Program Director and 2 Associate Program Directors, who will also serve as leaders of the training units, as well as 2 additional members who will provide specific guidance on clinical/epidemiologic research and on achieving and maintaining diversity within the training program. We have also assembled an outstanding roster of internal and external advisory board members with a mandate to evaluate the program and provide specific recommendations to improve both its quality and efficiency. The MRTP's highly personalized training program will include 1) individual development plans; 2) rigorous research training; 3) hands-on experience in cutting- edge methodologies; and 4) an integrated curriculum. Trainees will further benefit from the extensive institutional resources of WCM, MSKCC and RU. Based upon the growth in interest in our fellowship programs, we anticipate a substantial pool of highly qualified clinical and non-clinical candidates for the proposed MRTP, which will maintain a strong diversity focus. Through its rigorous, structured and highly personalized curriculum, this new training program seeks to train future leaders in digestive disease research who are prepared to translate their findings towards improving patient care in the United States.