Evaluating a Multilevel Communication Campaign to Increase HIV Vaccine Trial Enrollment
评估多层次沟通活动以增加艾滋病毒疫苗试验注册人数
基本信息
- 批准号:10625227
- 负责人:
- 金额:$ 65.12万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-05-19 至 2028-02-29
- 项目状态:未结题
- 来源:
- 关键词:AddressAdvertisingAffectAwarenessBehavioralBlack, Indigenous, People of ColorCOVID-19COVID-19 Prevention NetworkCOVID-19 pandemicCOVID-19 vaccineClassificationCollaborationsCommunicationCommunitiesDataDevelopmentDissemination and ImplementationEducational CurriculumEffectivenessElectronic MailEnrollmentFacebookFocus GroupsFundingFutureGoalsGovernmentHIVHIV Vaccine Trials NetworkHIV vaccineHealthHealth ServicesInstagramInternationalInterruptionKnowledgeLesbian Gay Bisexual Transgender QueerLongterm Follow-upMarketingMeasuresMedia CampaignMedical ResearchMisinformationModelingOutcomeParticipantPatient RecruitmentsPerformancePhasePhase III Clinical TrialsPopulation HeterogeneityPositioning AttributePreventiveProtocols documentationPublished CommentRegistriesResearchResearch PersonnelSeriesSurveysTaxonomyTestingTimeTrainingTrustTwitterUnited StatesVaccine Clinical TrialVaccinesVisitWorkclinical research siteclinical trainingcombatcommunity based participatory researchcommunity engagementcommunity partnershipdesignearly phase trialefficacy testingeligible participantequity, diversity, and inclusionevidence baseexperienceforginghealth communicationimplementation researchimprovedinnovationmarginalized communitymultidisciplinaryoutreachparticipant enrollmentprimary outcomeprogramsrecruitseropositivesocial mediasocial stigmatrend analysistrial enrollmenttrustworthinessvaccine hesitancyvaccine trialvirtualweb site
项目摘要
Project Summary/Abstract
The HIV Vaccine Trials Network (HVTN) has experienced significant challenges recruiting
participants in early-stage HIV vaccine clinical trials. Formidable barriers to participation
in HVTN preventive HIV early phase trials, including lack of HIV public urgency, numerous
study visits, long-term follow-up, vaccine induced seropositivity and HIV stigma, have
resulted in significant challenges enrolling participants into these trials. We will co-refine
an existing media campaign, develop, test and evaluate a multilevel communication
strategy to address some of these crucial concerns and strengthen our reputation of
trustworthiness in marginalized communities disproportionately affected by HIV to
increase their enrollment into early-stage HIV vaccine trials. Over the next 7 years, the
HVTN will focus on the early phase trial program to move the field forward and to identify
products efficiently and effectively for later efficacy testing. This will require the
development and deployment of evidence-based strategies to combat misinformation and
to strengthen community engagement. Our team and the clinical research sites in our
Network have forged longstanding community partnerships with diverse stakeholders.
During our phase 3 clinical trials for the US government-funded COVID-19 vaccine clinical
trials we developed new strategies to supplement our community engagement program:
(1) a consumer-driven marketing and advertising campaign; (2) virtual town halls and
listening sessions; and (3) the use of expert panels to review protocols and provide
guidance and direction. We will build on this work to inform our HIV strategy. We
assembled an experienced team of diverse researchers to accomplish the following aims:
1) Identify components of an initial media campaign that impact HIV vaccine trial
registration and develop a multilevel communication strategy; 2) Evaluate the impact of
the multilevel communication strategy on Phase I HIV vaccine trial registration; and 3)
Determine if the multilevel communication strategy generates public engagement with
vaccines and vaccine trials. This project will be the first large-scale communication study
conducted in the United States to improve community awareness of and engagement
with HIV vaccine trial research. It will assess misinformation and engagement with this
strategy to inform current and future HIV vaccine trials recruitment and is expected to
have a positive health impact by establishing robust strategies to improve diversity,
equity, and inclusion in Phase 1 preventive HIV vaccine trials.
项目总结/摘要
艾滋病毒疫苗试验网络(HVTN)在招募方面遇到了重大挑战
参与早期艾滋病毒疫苗临床试验的人。参与的巨大障碍
在HVTN预防艾滋病毒早期阶段试验中,包括缺乏艾滋病毒公共紧迫性,许多
研究访问、长期随访、疫苗诱导的血清阳性和艾滋病毒污名,
导致招募参与者进入这些试验的重大挑战。我们将共同完善
现有的媒体活动,开发,测试和评估多层次的沟通
解决其中一些关键问题的战略,并加强我们的声誉,
在受艾滋病毒影响不成比例的边缘化社区,
增加早期HIV疫苗试验的注册人数。在接下来的7年里,
HVTN将专注于早期阶段的试验计划,以推动该领域的发展,并确定
高效和有效地为以后的功效测试产品。这将需要
制定和部署循证战略,打击错误信息,
加强社区参与。我们的团队和我们的临床研究中心
网络与不同的利益攸关方建立了长期的社区伙伴关系。
在我们的美国政府资助的COVID-19疫苗临床3期临床试验期间,
我们开发了新的策略来补充我们的社区参与计划:
(1)消费者驱动的营销和广告活动;(2)虚拟市政霍尔斯,
(3)利用专家小组审查议定书,
指导和方向。我们将在这项工作的基础上,为我们的艾滋病毒战略提供信息。我们
组建了一个由不同研究人员组成的经验丰富的团队,以实现以下目标:
1)确定影响艾滋病毒疫苗试验的初始媒体宣传活动的组成部分
注册并制定多层次的沟通策略; 2)评估
关于艾滋病毒疫苗第一阶段试验注册的多层次沟通策略;以及3)
确定多层次沟通战略是否能促进公众参与,
疫苗和疫苗试验。这个项目将是第一个大规模的通信研究
在美国进行,以提高社区对
艾滋病疫苗试验研究。它将评估错误信息和参与这一点
为当前和未来的艾滋病毒疫苗试验招募提供信息的战略,
通过制定强有力的战略来改善多样性,
公平,并纳入1期预防性艾滋病毒疫苗试验。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Michele Peake Andrasik其他文献
Michele Peake Andrasik的其他文献
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{{ truncateString('Michele Peake Andrasik', 18)}}的其他基金
Reducing HIV Disparities: Sexual Concurrency Communication for HIV Prevention amo
减少艾滋病毒差异:性行为同时沟通促进艾滋病毒预防
- 批准号:
8097112 - 财政年份:2010
- 资助金额:
$ 65.12万 - 项目类别:
Reducing HIV Disparities: Sexual Concurrency Communication for HIV Prevention amo
减少艾滋病毒差异:性行为同时沟通促进艾滋病毒预防
- 批准号:
7673468 - 财政年份:2008
- 资助金额:
$ 65.12万 - 项目类别:
Reducing HIV Disparities: Sexual Concurrency Communication for HIV Prevention amo
减少艾滋病毒差异:性行为同时沟通促进艾滋病毒预防
- 批准号:
7425134 - 财政年份:2008
- 资助金额:
$ 65.12万 - 项目类别:
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