T32 Cincinnati Pediatric Clinical Pharmacology Training Program
T32 辛辛那提儿科临床药理学培训计划
基本信息
- 批准号:10632253
- 负责人:
- 金额:$ 8.68万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-05-16 至 2026-04-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
PROJECT SUMMARY
This is a competitive renewal application for the continuation of a highly collaborative and successful pediatric
clinical pharmacology training program at Cincinnati Children's Hospital Medical Center and the University of
Cincinnati. The program will train a new generation of pediatric investigators to assume leadership roles in the
application of innovative, high impact quantitative clinical pharmacology approaches to improve the
development, rational use and tailoring of new and existing drug therapies for neonates, infants, children,
adolescents and young adults. The need for pediatric clinical pharmacology research and training has never
been greater. The T32 Training Program in Pediatric Clinical Pharmacology at Cincinnati Children's Hospital
Medical Center (CCHMC) is designed specifically to address this critical need. The program is based in the
Division of Clinical Pharmacology, which is jointly a unit within the Department of Pediatrics and the University
of Cincinnati, College of Medicine (UCCoM). The program outlined in this renewal application draws on strong
leadership and a diverse group of well-established faculty mentors actively involved in subspecialty clinical
pharmacology research, representing 18 divisions within the Department of Pediatrics, the Departments of
Pharmacology & Systems Physiology and Biomedical Informatics at the UCCoM, and the James L. Winkle
College of Pharmacy. The program has tremendous institutional support and takes advantage of broad areas
of distinction and resources within a uniquely collaborative environment. The T32 training program is
innovative and well aligned with the objectives outlined in the program announcement as it: (1) has a focus in
early and later phase studies in multiple and diverse pediatric populations through ongoing research
collaborations with all major pediatric subspecialties; (2) involves the application and development of
innovative quantitative methodologies such as PK/PD modeling and pharmacometrics, quantitative systems
pharmacology modeling and simulation and model-informed clinical trial design; (3) is embedded in the
institutional and UCCoM pharmacogenetic/genomics research and training endeavors through the Center for
Pediatric Genomics; (4) is closely integrated with Bioinformatics and Health Services and Outcomes Research;
and (5) can rely on over 10 years of a well-established curriculum after two funding cycles as a successful
training program. The program provides a unique training experience to MDs, PharmDs, and PhDs to become
the next generation of leaders whose work will advance pediatric clinical pharmacology and to have an
extraordinary impact on pediatric therapeutics and health outcomes for children. The program has successfully
opened new avenues to enlarge the pool of talented young clinical investigators with a career interest in
pediatric therapeutics.
项目概要
这是一个有竞争力的续订申请,旨在延续高度协作和成功的儿科
辛辛那提儿童医院医学中心和辛辛那提大学临床药理学培训项目
辛辛那提。该计划将培训新一代儿科研究人员,让他们在儿科研究中担任领导角色。
应用创新的、高影响力的定量临床药理学方法来改善
为新生儿、婴儿、儿童开发、合理使用和定制新的和现有的药物疗法,
青少年和年轻人。对儿科临床药理学研究和培训的需求从未如此
更大。辛辛那提儿童医院儿科临床药理学 T32 培训项目
医疗中心 (CCHMC) 专为满足这一关键需求而设计。该计划基于
临床药理学部,是儿科和大学的联合单位
辛辛那提医学院 (UCCoM)。本续签申请中概述的计划借鉴了强大的
领导力和一群积极参与亚专业临床的知名教师导师
药理学研究,代表儿科、各科室的 18 个部门
UCCoM 的药理学与系统生理学和生物医学信息学以及 James L. Winkle
药学院。该计划拥有巨大的机构支持并利用广泛的领域
独特的协作环境中的区别和资源。 T32训练计划是
具有创新性,并且与计划公告中概述的目标高度一致,因为:(1) 重点关注
通过正在进行的研究,对多个不同的儿科人群进行早期和后期研究
与所有主要儿科亚专科合作; (2) 涉及应用和开发
创新的定量方法,例如 PK/PD 建模和药理学、定量系统
药理学建模和模拟以及基于模型的临床试验设计; (3) 嵌入到
通过该中心开展机构和 UCCoM 药物遗传学/基因组学研究和培训工作
儿科基因组学; (4) 与生物信息学和健康服务及结果研究紧密结合;
(5) 在两个资助周期后,可以依靠超过 10 年的完善课程作为成功的课程
培训计划。该计划为医学博士、药学博士和博士提供独特的培训经验,使他们能够成为
下一代领导者的工作将推进儿科临床药理学并拥有
对儿科治疗和儿童健康结果产生非凡影响。该计划已成功
开辟了新的途径,扩大对以下领域有职业兴趣的有才华的年轻临床研究人员的库
儿科治疗学。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Alexander A Vinks', 18)}}的其他基金
Cincinnati Pediatric Clinical Pharmacology Postdoctoral Training Program
辛辛那提儿科临床药理学博士后培训项目
- 批准号:
9918428 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Cincinnati Pediatric Clinical Pharmacology Postdoctoral Training Program
辛辛那提儿科临床药理学博士后培训项目
- 批准号:
9267170 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
T32 Cincinnati Pediatric Clinical Pharmacology Training Program
T32 辛辛那提儿科临床药理学培训计划
- 批准号:
10175275 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Cincinnati Training Program in Pediatric Clinical and Developmental Pharmacology
辛辛那提儿科临床和发育药理学培训计划
- 批准号:
8264542 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Cincinnati Pediatric Clinical Pharmacology Postdoctoral Training Program
辛辛那提儿科临床药理学博士后培训项目
- 批准号:
9547581 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Cincinnati Training Program in Pediatric Clinical and Developmental Pharmacology
辛辛那提儿科临床和发育药理学培训计划
- 批准号:
8122598 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Cincinnati Training Program in Pediatric Clinical and Developmental Pharmacology
辛辛那提儿科临床和发育药理学培训计划
- 批准号:
8468190 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Cincinnati Training Program in Pediatric Clinical and Developmental Pharmacology
辛辛那提儿科临床和发育药理学培训计划
- 批准号:
8860215 - 财政年份:2011
- 资助金额:
$ 8.68万 - 项目类别:
Optimizing MMF therapy in pediatric transplant patients
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- 批准号:
7094909 - 财政年份:2006
- 资助金额:
$ 8.68万 - 项目类别:
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