NEURAL SUBSTRATE OF INTERPERSONAL DYSFUNCTION IN BORDERLINE PERSONALITY DISORDER
NEURAL SUBSTRATE OF INTERPERSONAL DYSFUNCTION IN BORDERLINE PERSONALITY DISORDER
批准号:
7953732
负责人:
ANTONIA S NEW
金额:
$0.2万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-03-01 至 2009-07-31
关键词:
AffectAffectiveAggressive behaviorBehavioralBorderline Personality DisorderClinical ResearchComputer Retrieval of Information on Scientific Projects DatabaseDiseaseEmotionalEmpathyEventFaceFunctional Magnetic Resonance ImagingFunctional disorderFundingGrantIndividualInstitutionInterpersonal RelationsMajor Depressive DisorderMethodsMonitorPathologyPatternRegulationResearchResearch PersonnelResourcesSelf Destructive BehaviorSocial BehaviorSocial FunctioningSocial InteractionSourceSymptomsUnited States National Institutes of Healthblood oxygenation level dependent responsedepresseddesignexperienceinformation processingneural circuitrelating to nervous system
中文摘要
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This project proposes to examine the neural circuitry underlying components of emotional information processing and social functioning in individuals with borderline personality disorder, individuals with current Major Depressive Disorder and healthy control subjects. We propose to examine affective responsiveness through a face viewing task and empathy through observing pictures and rating the experience of the people depicted in the pictures, while gathering FMRI BOLD response in event-related task designs. We will also characterize the social behavior and interpersonal interactions of all subjects with a naturalistic monitoring of social interactions using a method called "Event Contingent Recording". We will examine group differences in the two fMRI tasks and in the social interactions of the subjects. Borderline Personality Disorder (BPD) is a disabling disorder characterized by dysfunction in affect regulation and impulse control often resulting in impaired interpersonal relationships and maladaptive behavioral patterns including aggression and self-destructive behavior. Major Depressive Disorder is similar to BPD in that it involves dysphoric affect, but individuals with MDD do not tend to have the same level of interpersonal symptoms that are seen in BPD. Including individuals with both MDD and BPD will allow us to tease apart the effect of depressed affect from more fundamental borderline pathology.
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MIFEPRISTONE AFTER TRAUMA TO ENHANCE RESILIENCE (MATTER)
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批准号:7953718
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资助金额:$0.17万
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财政年份:2009
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负责人:ANTONIA S NEW
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REGIONAL BRAIN CONTROL OF LABORATORY INDUCED AGGRESSION AS ASSESSED BY FDG PET
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资助金额:$0.34万
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财政年份:2008
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负责人:ANTONIA S NEW
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依托单位:
WOMEN RESILIENCE TO TRAUMA: FMRI STUDY OF EMOTION
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批准号:7718134
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项目类别:
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资助金额:$1.14万
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财政年份:2008
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负责人:ANTONIA S NEW
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依托单位:
MIFEPRISTONE AFTER TRAUMA TO ENHANCE RESILIENCE (MATTER)
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批准号:7718208
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项目类别:
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资助金额:$0.29万
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财政年份:2008
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负责人:ANTONIA S NEW
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依托单位:
WOMEN RESILIENCE TO TRAUMA: FMRI STUDY OF EMOTION
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批准号:7605308
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资助金额:$2.19万
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财政年份:2007
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负责人:ANTONIA S NEW
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依托单位:
REGIONAL BRAIN CONTROL OF LABORATORY INDUCED AGGRESSION AS ASSESSED BY FDG PET
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批准号:7605270
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项目类别:
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资助金额:$2.31万
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财政年份:2007
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负责人:ANTONIA S NEW
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依托单位:
GUANFACINE IN THE TREATMENT OF BORDERLINE PERSONALITY DISORDER
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批准号:7605364
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项目类别:
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资助金额:$0.3万
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财政年份:2007
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负责人:ANTONIA S NEW
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依托单位:
FMRI AND EMOTION IN PERSONALITY DISORDER PATIENTS
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批准号:7605289
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项目类别:
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资助金额:$0.06万
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财政年份:2007
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负责人:ANTONIA S NEW
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依托单位:
WOMEN RESILIENCE TO TRAUMA: FMRI STUDY OF EMOTION
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批准号:7380570
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项目类别:
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资助金额:$1.18万
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财政年份:2006
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负责人:ANTONIA S NEW
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依托单位:
REGIONAL BRAIN CONTROL OF LABORATORY INDUCED AGGRESSION AS ASSESSED BY FDG PET
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批准号:7380512
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项目类别:
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资助金额:$1.56万
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财政年份:2006
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负责人:ANTONIA S NEW
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依托单位:
FMRI AND EMOTION IN PERSONALITY DISORDER PATIENTS
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批准号:7380547
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项目类别:
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资助金额:$0.32万
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财政年份:2006
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负责人:ANTONIA S NEW
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依托单位:
STEROID HORMONES AND IMPULSIVE AGGRESSION
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批准号:7202473
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资助金额:$0.79万
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财政年份:2005
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依托单位:
NEW DIRECTIONS IN THE GENETICS OF IMPULSIVITY AND AGGRESSION
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批准号:7202457
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项目类别:
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资助金额:$3.14万
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财政年份:2005
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负责人:ANTONIA S NEW
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依托单位:
REGIONAL BRAIN CONTROL OF LABORATORY INDUCED AGGRESSION AS ASSESSED BY FDG PE
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批准号:7202467
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项目类别:
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资助金额:$1.69万
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财政年份:2005
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负责人:ANTONIA S NEW
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依托单位:
Regional Brain Control of Laboratory Induced Aggression as Assessed by FDG PE...
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批准号:7044835
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项目类别:
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资助金额:$1.92万
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财政年份:2004
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负责人:ANTONIA S NEW
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依托单位:
Steroid Hormones and Impulsive Aggression
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批准号:7044851
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项目类别:
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资助金额:$1.67万
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财政年份:2004
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负责人:ANTONIA S NEW
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依托单位:
New Directions in the Genetics of Impulsivity and Aggression
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批准号:7044815
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项目类别:
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资助金额:$5.82万
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财政年份:2004
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负责人:ANTONIA S NEW
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依托单位:
FDG PET Study of Laboratory Induced Aggression
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项目类别:
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资助金额:$37.24万
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财政年份:2003
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负责人:ANTONIA S NEW
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依托单位:
海外基金