CTSA K12 Program at Indiana University

项目总结/摘要 印第安纳州临床和转化科学研究所（CTSI）在以下方面取得了持续的成就： 通过其劳动力发展计划准备早期职业学者。自2008年以来，我们的项目 准备了72名来自我们国家的三个主要研究型大学的KL 2学者，其中大部分保留在学术 职位（90%）和获得外部资金作为主要研究者（81%），包括36个R 01，36个其他R- 级别奖励，以及26 K或同等职业奖励。我们计划的全州范围确保了广泛的， 多元化的学者，教师导师和翻译研究的广度。 印第安纳州新的K12指导研究职业发展计划的主要目标是 CTSI是提供一个早期职业教师学者密集辅导职业发展的多元化群体 导致研究独立的经验，并为他们在临床和 转化科学为了最大限度地提高K12计划的影响，我们设计了我们的拟议计划， 解决临床和转化科学的六个核心领域，包括核心知识，基于团队的科学， 领导力/管理、指导培训、多样性和职业能见度/提升。保护时间 密集的指导研究活动与所需的课程内容和广泛的 利用可用的印第安纳州CTSI资源的选修经验，并最终根据 学者个人需要。这些组成部分结合在一起，确保了早期培训的基本技能， 职业临床和转化研究科学家。鉴于代表性不足的比例处于历史低位， 个人进入科学事业，我们建议有意的循证努力继续招聘， 支持和资助这些人。我们的目标不仅是维持我们目前的多样性指标， 我们的学术机构，但更接近我们国家人口的多样性。我们 为实现K12计划目标，提出以下目标： 1)支持和加速学者过渡到临床和转化研究的独立职业。 2)在整个KL 2计划中促进多样性，公平性和包容性（DEI）的努力，以推动 学者，他们的团队和他们的翻译工作的多样性。 3)利用机构优势和CTSA中心伙伴关系， 发展，包括职业知名度和提升。 我们预计在5年内资助25名学者，每位学者在K12上花费两年时间， 目标是获得联邦资助的K或R级补助金。我们有成功获得机构资金的历史 支持更多的学者（增加多达50%的职位）。我们相信我们的 拟议的计划将吸引多样化，高素质的申请人，并指导他们发展有影响力的 临床和转化科学的职业生涯。

Project Summary/Abstract The Indiana Clinical and Translational Sciences Institute (CTSI) has a sustained record of accomplishment in preparing early career Scholars through its workforce development program. Since 2008, our program has prepared 72 KL2 Scholars from our state's three major research universities with most retained in academic positions (90%) and obtaining external funding as principal investigators (81%) including 36 R01s, 36 other R- level awards, and 26 K or equivalent career awards. The state-wide reach of our program ensures a broad, diverse pool of Scholars, faculty mentors, and breadth of translational research. The primary objective of this new K12 Mentored Research Career Development Program at the Indiana CTSI is to provide a diverse group of early career faculty Scholars intensive mentored career development experiences that lead to research independence and prepare them for leadership positions in clinical and translational science. To maximize K12 programmatic impact we have designed our proposed program to address six core areas of clinical and translational science including core knowledge, team-based science, leadership/management, mentoring training, diversity, and career visibility/enhancement. Protected time for intensive mentored research activity is carefully balanced with required curricular content and a broad range of elective experiences that capitalize on available Indiana CTSI resources and ultimately are selected based on individual Scholar needs. Taken together these components assure training in a fundamental skillset for early career clinical and translational research scientists. Given the historically low rates of underrepresented individuals moving into scientific careers, we propose intentional evidence-based efforts to continue to recruit, support, and fund these individuals. Our goal is to not only sustain our current diversity metrics, which exceed those of our academic institutions, but to resemble the diversity of our state's population more closely. We propose the following aims to achieve K12 program goals: 1) Support and accelerate Scholar transition to independent careers in clinical and translational research. 2) Catalyze Diversity, Equity, and Inclusion (DEI) efforts throughout the KL2 program to advance the diversity of Scholars, their teams, and their translational work. 3) Leverage institutional strengths and companion CTSA hub partnerships to optimize Scholar development including career visibility and enhancement. We anticipate funding 25 Scholars over 5 years with each Scholar spending two years on the K12, with the goal to obtain a federally funded K or R level grant. We have a successful history of securing institutional funds to support additional Scholars (increasing the positions offered by as much as 50%). We are confident that our proposed program will attract diverse, high caliber applicants and mentor them toward developing impactful careers in clinical and translational science.