Women focused Encounters for Resilience, Independence, Strength and Eudaimonia (WE RISE)
以女性为中心的韧性、独立、力量和幸福的邂逅 (WE RISE)
基本信息
- 批准号:10744678
- 负责人:
- 金额:$ 77.25万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-08-15 至 2028-05-31
- 项目状态:未结题
- 来源:
- 关键词:AbstinenceAccelerometerAcquired Immunodeficiency SyndromeAddressAdherenceAnxietyBehavior TherapyCaringCollectionCommunitiesComplementDiagnosticDiagnostic FactorEconomicsEducationEffectivenessEpidemicEvaluationExclusionExerciseExercise TherapyExploration, Preparation, Implementation, and SustainmentFeedbackFocus GroupsGenderGoalsHIVHIV/AIDSHealthHealth Services AccessibilityHybridsIndividualInterventionInterviewLonelinessMaintenanceMeasuresMediatorMeditationMental DepressionMethodsModificationMoodsMorbidity - disease rateNeighborhoodsOutcomeParticipantPeriodicalsPersonsPharmaceutical PreparationsPhasePreparationProcessProviderRandomizedReach, Effectiveness, Adoption, Implementation, and MaintenanceReduce health disparitiesReportingResearchResourcesRiskSelf EfficacySiteSocial supportTimeTrainingTraumaViolenceViralVisitWithdrawalWomanantiretroviral therapybarrier to carebehavior changecommunity organizationscoping mechanismeducation accesseffectiveness evaluationeffectiveness researchefficacious interventionempowermentexperienceflexibilitygirlshealth care availabilityhealth disparityhybrid type 1 studyimplementation frameworkimplementation processimplementation strategyimprovedintervention effectmenmindfulnessoutcome disparitiespeerpeer supportpsychologicracismresiliencesocialsocial disparitiessocial stigmastandard of caresubstance usesubstance use treatmentsustainability frameworksyndemictherapy adherencetrauma symptomviolence against womenwomen of color
项目摘要
Project Abstract
Women represent the majority of people living with HIV in the world. Yet the underrepresentation of women in
HIV research persists despite them experiencing greater societal/social disparities of health (SSDoH) including
HIV care access and poorer HIV outcomes when compared to men. The coming together of substance
(ab)use, violence against women and girls (trauma), and AIDS/HIV (known as SAVA) in the context of SSDOH
contributes to excess HIV associated morbidity in women living with and at risk for HIV. This proposal aims to
improve HIV outcomes in women living with HIV (WLWH) by evaluating the effectiveness and implementation
of a combination intervention addressing substance use, trauma, and HIV.
We will employ a randomized Type1 Hybrid study evaluating the effectiveness of acceptance and commitment
therapy, exercise, and social support delivered by peer navigators. Implementation strategies that carry the
potential to address SSDoH (economic insecurity, limited healthcare access, limited community) that WLWH
experience and may enhance sustainability and dissemination will be evaluated. Community-based
organizations in four Ending the HIV Epidemic jurisdictions will employ the intervention for a total of 48 weeks
per site. The first 24 weeks (research effectiveness) will include a randomized study of 40 WLWH and will
evaluate the impact on HIV (ART adherence, % continuous viral suppression), substance use (days and
amount of use), trauma (trauma symptoms) and factors common to all three conditions (mood, social
disconnection) over time. Weeks 24-48 will include a research implementation phase guided by the
Exploration, Preparation, Implementation and Sustainment (EPIS) framework evaluating local barriers,
facilitators, change in implementation strategies selected to address structural/social disparities of health and
intervention adaptations using the the Framework for Recording Adaptations and Modifications-Enhanced
(FRAME). The following aims will guide evaluation of our intervention referred to as women focused
encounters for resilience, independence, strength and eudaimonia (WE RISE).
Aim 1: Evaluate short (week 8) and longer term (weeks 12, 24) effectiveness of WE RISE on HIV (↑ ART
adherence, ↑ % of participants with continuous viral suppression), trauma (↓ trauma symptoms), substance use
(↓ days of substance use) and transdiagnostic factors such as mood (↓depression, ↓anxiety) and social
connectedness.
Aim 2: Document the WE RISE implementation process by characterizing reach, effectiveness, adoption,
implementation and maintenance (RE-AIM) by site for 24 weeks.
Aim 3: At completion of 24 and 48 weeks, transcreate alternate or additional implementation strategies that
address local barriers and leverage facilitators to optimize the effectiveness, maintenance and broader
dissemination of WE RISE and document site-specific adaptations FRAME.
项目摘要
妇女占世界艾滋病毒感染者的大多数。然而,妇女代表性不足,
艾滋病毒研究持续存在,尽管他们经历了更大的社会/社会健康差距(SSDoH),包括
与男性相比,艾滋病毒护理的获得和艾滋病毒结果较差。物质的聚集
(ab)在苏丹卫生部范围内的吸毒、暴力侵害妇女和女童(创伤)以及艾滋病/艾滋病毒(称为SAVA)
导致感染艾滋病毒和有感染艾滋病毒风险的妇女的艾滋病毒相关发病率过高。这项建议旨在
通过评估有效性和执行情况,改善感染艾滋病毒妇女的艾滋病毒防治成果
药物使用、创伤和艾滋病的综合干预。
我们将采用一项随机1型混合研究,评估接受和承诺的有效性
治疗、锻炼和同伴导航员提供的社会支持。执行战略,
解决SSDoH(经济不安全,医疗保健服务有限,社区有限)的潜力,WLWH
将对经验和可能加强可持续性和传播的经验进行评价。基于社区
四个终止艾滋病毒流行管辖区的组织将采用总共48周的干预措施
每个站点。前24周(研究有效性)将包括40名WLWH的随机研究,
评估对HIV(ART依从性、持续病毒抑制率)、物质使用(天数和
使用量)、创伤(创伤症状)和所有三种情况的共同因素(情绪、社会
断开连接)。第24-48周将包括一个研究实施阶段,
评估当地障碍的勘探、准备、实施和维持框架,
促进者,改变选定的执行战略,以解决健康和
使用增强的改编和修改记录框架进行干预改编
(框架)。以下目标将指导对我们称为“以妇女为重点”的干预措施的评估
为适应力,独立性,力量和eudaimonia(我们崛起)的遭遇。
目的1:评估WE RISE对HIV(↑ ART)的短期(第8周)和长期(第12、24周)有效性
依从性,持续病毒抑制的受试者百分比↑),创伤(↓创伤症状),物质使用
(物质使用天数↓)和转诊断因素,如情绪(抑郁↓,焦虑↓)和社会
连通性
目标2:通过描述覆盖范围、有效性、采用率,
由站点实施和维护(RE-AIM)24周。
目标3:在完成第24周和第48周的培训后,
解决当地的障碍,并利用促进者来优化效率,维护和更广泛的
传播WE RISE并记录特定场地的适应性FRAME。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Maile Ann Young Karris其他文献
Maile Ann Young Karris的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Maile Ann Young Karris', 18)}}的其他基金
Acceptance and commitment therapy to address the psychosocial co-morbidities of chronic pain in aging people living with HIV
接受和承诺疗法可解决老年艾滋病毒感染者慢性疼痛的心理社会并发症
- 批准号:
9762827 - 财政年份:2018
- 资助金额:
$ 77.25万 - 项目类别:
相似海外基金
Establishing best practices for the use of accelerometer measured ambient light sensor data to assess children's outdoor time
建立使用加速度计测量的环境光传感器数据来评估儿童的户外时间的最佳实践
- 批准号:
10731315 - 财政年份:2023
- 资助金额:
$ 77.25万 - 项目类别:
Training of machine learning algorithms for the classification of accelerometer-measured bednet use and related behaviors associated with malaria risk
训练机器学习算法,用于对加速计测量的蚊帐使用和与疟疾风险相关的相关行为进行分类
- 批准号:
10727374 - 财政年份:2023
- 资助金额:
$ 77.25万 - 项目类别:
Development of environmentally robust and thermally stable Microelectromechanical Systems (MEMS) based accelerometer for automotive applications
开发适用于汽车应用的环境稳定且热稳定的微机电系统 (MEMS) 加速度计
- 批准号:
566730-2021 - 财政年份:2022
- 资助金额:
$ 77.25万 - 项目类别:
Alliance Grants
Use of accelerometer and gyroscope data to improve precision of estimates of physical activity type and energy expenditure in free-living adults
使用加速度计和陀螺仪数据来提高自由生活成年人身体活动类型和能量消耗的估计精度
- 批准号:
10444075 - 财政年份:2022
- 资助金额:
$ 77.25万 - 项目类别:
Use of accelerometer and gyroscope data to improve precision of estimates of physical activity type and energy expenditure in free-living adults
使用加速度计和陀螺仪数据来提高自由生活成年人身体活动类型和能量消耗的估计精度
- 批准号:
10617774 - 财政年份:2022
- 资助金额:
$ 77.25万 - 项目类别:
Investigating the validity and reliability of accelerometer-based measures of physical activity and sedentary time in toddlers (iPLAY)
研究基于加速度计的幼儿体力活动和久坐时间测量的有效性和可靠性 (iPLAY)
- 批准号:
475451 - 财政年份:2022
- 资助金额:
$ 77.25万 - 项目类别:
Studentship Programs
Exploration of novel pathophysiology of chemotherapy-induced peripheral neuropathy utilizing quantitative sensory testing and accelerometer
利用定量感觉测试和加速度计探索化疗引起的周围神经病变的新病理生理学
- 批准号:
22K17623 - 财政年份:2022
- 资助金额:
$ 77.25万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Investigating the reliability of accelerometer-based measures of physical activity and sedentary time in toddlers
研究基于加速度计的幼儿体力活动和久坐时间测量的可靠性
- 批准号:
466914 - 财政年份:2021
- 资助金额:
$ 77.25万 - 项目类别:
Studentship Programs
Doctoral Dissertation Research: Leveraging Intensive Time Series of Accelerometer Data to Assess Impulsivity and Inattention in Preschool Children
博士论文研究:利用加速计数据的密集时间序列来评估学龄前儿童的冲动和注意力不集中
- 批准号:
2120223 - 财政年份:2021
- 资助金额:
$ 77.25万 - 项目类别:
Standard Grant
Development of a rotation-invariant accelerometer for human activity recognition
开发用于人类活动识别的旋转不变加速度计
- 批准号:
21K19804 - 财政年份:2021
- 资助金额:
$ 77.25万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)