权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Investigating interference-control in ADHD using a novel forced-response method

使用新颖的强制响应方法研究 ADHD 的干扰控制

基本信息

批准号：
10591920
负责人：
John Jonides
金额：
$ 23.4万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-01-01 至 2024-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10591920
关键词：
Address Adolescent Adopted Adult Advisory Committees Affect Age Attention deficit hyperactivity disorder Attentional deficit Behavioral Child Clinical Computer Models Conflict (Psychology)Control Groups Data Diagnosis Diagnostic Disease Education Failure Functional disorder Gender General Population Goals Home Impairment Individual Individual Differences Life Literature Methodology Methods Modeling Neurodevelopmental Disorder Participant Patient Self-Report Patients Persons Predisposition Process Production Research Resources Rest Sampling Source Stimulus Stream Symptoms Testing Time Work clinical diagnosis computer framework critical period design executive function experimental study individual response novel novel strategies parallel processing prevent processing speed psychologic public health relevance recruit response screening

项目摘要

PROJECT SUMMARY Attention deficit/hyperactivity disorder (ADHD) is often considered to be a disorder in children and adolescents, but is, in fact, diagnosed in 2.5% of adults as well. A main behavioral correlate of ADHD is the claimed increase in susceptibility to interference from irrelevant external sources. A prevailing view in the literature is that deficits in executive functions, especially control over interference, underlie ADHD symptoms (e.g., Barkley, 1997; Pennington & Ozonoff, 1996). Interference control is the ability to prevent interference due to resource or stimulus competition (Nigg, 2000). However, despite 20 years of research, empirical evidence for impaired interference control in ADHD patients remains inconclusive using model tasks such as the Simon task and the flanker task. This may be related to methodological issues that are present in such tasks that are typically used to assess interference control. The current application is based on a new approach to study interference control that can avoid these issues. The approach makes use of a “forced-response” method in which individuals’ responses in conflict tasks are required at a fixed time. This fixed time occurs at a variable time after the presentation of the imperative stimulus to which individuals must make a response, making it possible to capture responses at various points in the processing stream. The application includes experiments using this new approach, and it offers a computational framework to understand how interference control in ADHD individuals may be compromised compared to healthy individuals.

项目总结