CORIELL - NINDS HUMAN GENETICS RESOURCE CENTER

CORIELL - NINDS 人类遗传学资源中心

• 批准号: 10930767
• 负责人: LAURA SCHEINFELDT
• 金额: $ 150.61万
• 依托单位: CORIELL INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2024-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10930767
• 关键词: Academia; Biological; Catalogs; Cell Line; Cerebrovascular Disorders; Clinical; Communities; DNA; Data; Data Set; Dedications; Diagnosis; Dystonia; Ensure; Epilepsy; Equipment and supply inventories; Funding; Genetic; Genotype; Gilles de la Tourette syndrome; Goals; Human Genetics; Individual; Industry; Infrastructure; Motor Neuron Disease; National Institute of Neurological Disorders and Stroke; Neurologic; Nonprofit Organizations; Parkinsonian Disorders; Phenotype; Policies; Process; Research Personnel; Resources; Sampling; Scientist; Standardization; Subjects Selections; System; United States National Institutes of Health; data exchange; data interoperability; data sharing; database of Genotypes and Phenotypes; genetic resource; lymphoblastoid cell line; nervous system disorder; repository; web site

"The NINDS DNA and Cell Line Repository (hereinafter “NINDS repository”), established in 2002, receives, processes, curates, stores, and distributes genetic samples and accompanying clinical and genotypic data to the scientific community. Samples are available to researchers from academia, industry, and non-profit organizations. Currently, the NINDS repository contains DNA samples, lymphoblastoid cell lines (LCL), and DNA 96-well plates (panels) from more than 51,000 well phenotyped unique individuals diagnosed with neurological disorders (cerebrovascular diseases, dystonia, epilepsy, motor neuron diseases, Parkinsonism, or Tourette syndrome), or from neurologically normal controls. These materials were collected and generated over many years from NINDS-funded studies that carefully selected subjects, and many of the samples are available in a finite quantity."

“NINDS DNA和细胞系储存库（以下简称“NINDS储存库”）成立于2002年，负责接收、处理、管理、储存和向科学界分发遗传样本以及附带的临床和基因型数据。样本可供学术界、工业界和非营利组织的研究人员使用。目前，NINDS储存库包含来自51，000多个被诊断患有神经系统疾病（脑血管疾病、肌张力障碍、癫痫、运动神经元疾病、帕金森症或抽动秽语综合征）或来自神经系统正常对照的表型独特个体的DNA样本、淋巴母细胞样细胞系（LCL）和DNA 96孔板（板）。这些材料是多年来从NINDS资助的研究中收集和生成的，这些研究仔细选择了受试者，许多样本都是有限数量的。"