Midcareer K24 Award for Mentoring and Patient-Oriented Research

职业生涯中期 K24 指导和以患者为导向的研究奖

• 批准号: 10618740
• 负责人: PHILLIP O COFFIN
• 金额: $ 20.25万
• 依托单位: SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-01 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10618740
• 关键词: Absence of pain sensation; Acceleration; Affect; Animals; Behavior Therapy; Benefits and Risks; Caring; Characteristics; Cocaine; Data; Data Set; Development; Disease; Ecological momentary assessment; Elderly; Enrollment; Event; Failure; Female; Funding; Gender; HIV; Healthcare Systems; Heroin; Hour; Human; Intervention; Interview; Longitudinal cohort study; Mental Health; Mentors; Methamphetamine; Methamphetamine overdose; Mid-Career Clinical Scientist Award (K24); Modeling; Morbidity - disease rate; Motivation; Naloxone; National Institute of Drug Abuse; Neuropathy; Opioid; Opioid Analgesics; Overdose; Pain; Pain Nature; Pain Research; Pain intensity; Pain management; Palliative Care; Participant; Patients; Peripheral Nervous System Diseases; Persons; Pharmaceutical Preparations; Poisoning; Postoperative Period; Primary Care; Qualitative Methods; Reading; Reporting; Research; Research Personnel; Rewards; Risk; San Francisco; Science; Self Care; Self Management; Social isolation; Source; Stimulant; Time; Toxic effect; Training; Voice; career; chronic pain; chronic pain patient; clinical practice; cohort; experience; experimental study; faculty mentor; implementation science; improved; methamphetamine effect; methamphetamine use; mortality; non-cancer chronic pain; novel; novel strategies; opioid use; overdose death; painful neuropathy; patient oriented; patient oriented research; pharmacologic; pleasure; poor health outcome; prescription opioid; reduced substance use; response; social; stimulant use; substance use; suicide mortality; transmission process; trial design; viral transmission

Project Summary/Abstract This K24 award will support the candidate’s development as a mentor and substance use investigator, while completing a novel study of the use of non-prescribed stimulants in the self-care of chronic pain, particularly among people living with HIV and neuropathic pain. The candidate will complete training in mentoring through differentness to further enhance his ability to mentor trainees underrepresented in science, while also developing and delivering a training targeted for mentors not underrepresented, in order to improve the pipeline of senior mentors who can effectively mentor underrepresented trainees. He will also enhance his abilities to conduct substance use research by obtaining additional training in implementation science, ecological momentary assessment, adaptive trial design, and pain research. He will undertake directed reading with experts in pain research and in mentoring. In addition, the candidate will pursue new research to examine the phenomenon of non-prescribed stimulant use self-care of chronic pain. The candidate will enroll 50 people living with HIV and neuropathic pain who report methamphetamine use for pain self-care for 6 months of ecological momentary assessments, to determine the relationship between use and functional pain. The candidate will conduct qualitative interviews with 30 of the participants to explore the nature of the pain and relationship between physical and social pain, as well as the perceived risks and benefits to methamphetamine use. Finally, he will compare those who do not use stimulants, who use stimulants for pain, and who use stimulants for other reasons from his longitudinal cohort study of patients with chronic pain to establish longitudinal effects of methamphetamine use for pain self-care.

项目总结/文摘