GEROSCIENCE TRAINING PROGRAM IN OKLAHOMA

摘要 衰老和年龄相关疾病的病因学知之甚少。在过去的30年里， 我们对衰老在许多疾病发展中的关键作用的理解取得了令人印象深刻的进展 这限制了生活质量。与年龄相关的衰老和疾病显然会导致依赖性和严重的 健康寿命缩短;然而，如果不清楚衰老和疾病之间的相互作用， 无法开发出有效的治疗方法。我们的GeroScience培训计划于2017年启动， 培训下一代研究人员的方法，以解决衰老的复杂原因及其 与年龄相关疾病的相互作用。我们最初请求支持3名博士预科生和4名博士后 16名教师。在过去的4年里，该计划利用这一支持，共培训了8名预科生， 博士研究生和9名博士后研究生。在这最初的资助期间， 在2005年的计划中继续扩大。特别重要的是，由于我们的学员 被T32项目录取后，他们将接受严格的培训计划，并被要求撰写资助申请书。 来支持他们的研究计划重要的是，由于联邦资助， 或协会赞助的奖项继续参与，并受益于，整体培训计划， 我们已经建立。同样，我们的导师每年都会重新认证，我们制定了一个培训计划， 年轻的导师博士预科生：在8名博士预科生中，有7名进入我们的课程， 正在步入正轨或已完成博士学位。百分之七十五（75%）的博士预科生（6）有 书面赠款申请，提交申请的人100%得到资助。重要的是， 主要是F31，R36和AHA赠款。这些受训人员迄今已出版了4.12种出版物。博士后 研究员：在九（9）博士后候选人中，七（7）名研究员迄今已提交赠款，其中， 57%的人获得了资助。迄今为止，受训人员平均发表8.91篇文章。我们绝大多数的学生 他们的演讲赢得了当地和国家的奖项。那些毕业的人已经找到了工作 在学术界和制药界都是如此根据我们的成功程度，目前的人口普查和计划 为了继续扩大我们的项目，我们已经将指导教师增加到21人，并要求4人 研究生和4个博士后实习生职位，以继续我们在GeroScience的培训。

ABSTRACT The etiology of aging and age-related disease is poorly understood. Over the past 3 decades, there have been impressive advances in our understanding of the critical role of aging in the development of many diseases that limit quality of life. Aging and diseases associated with age clearly result in dependence and a severe reduction in health-span; however, without a clear understanding of the interactions between aging and disease, effective therapies cannot be developed. Our training program in GeroScience was initiated in 2017 as a new approach to training the next generation of researchers to address the complex causes of aging and their interactions with age-related disease. We originally requested support for 3 pre-doctoral and 4 post-doctoral fellows for 16 faculty. Over the last 4 years, the program has leveraged this support to train a total of 8 pre- doctoral trainees and 9 post-doctoral trainees. The total number of trainees during this initial funding period will continue to expand in the -05 year of the program. It is particularly important to note that as our trainees are accepted to the T32 program, they undergo a rigorous training plan and are required to write grant applications to support their proposed research. Importantly, trainees that rotate off our T32 due to the funding of their Federal or Association sponsored awards continue to participate in, and benefit from, the overall training program that we have established. Similarly, our mentors are recertified each year and we have developed a program to train young mentors. Predoctoral Students: Of the 8 pre-doctoral students that have entered our program, seven (7) are on-track or have completed their PhD. Seventy-five percent (75%) of the pre-doctoral students (6) have written grant applications and, of those submitting applications, 100% have been funded. Importantly, these are primarily F31, R36, and AHA grants. These trainees have produced 4.12 publications to date. Post-Doctoral Fellows: Of the nine (9) post-doctoral candidates, seven (7) fellows have submitted grants thus far and, of these, 57% have received funding. The trainees average 8.91 publications to date. The vast majority of our students have won local and national awards for their presentations. Those that have graduated have found employment in both academic and pharmaceutical environments. Based on our level of success, current census and plans for continued expansion of our program, we have increased our mentoring faculty to 21 and are requesting 4 graduate and 4 post-doctoral trainee positions to continue our training in GeroScience.