Oklahoma Center for Respiratory and Infectious Diseases
Oklahoma Center for Respiratory and Infectious Diseases
批准号:
10628212
负责人:
LIN LIU
金额:
$110.11万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-07-05 至 2028-06-30
关键词:
AddressAffectAnimal ModelApplications GrantsAreaAwardBacterial InfectionsBiomedical EngineeringBiomedical ResearchCOVID-19COVID-19 pandemicCenters of Research ExcellenceCessation of lifeCollaborationsCommunicable DiseasesCommunitiesCore FacilityDevelopmentDiagnosticDiseaseEnvironmentEquipmentFacultyFinancial SupportFoundationsFundingGoalsGrantInfectionInfectious Diseases ResearchInfluenzaInstitutionJournalsLung infectionsMedical ResearchModernizationMolecular BiologyMycosesOklahomaPaperPathogenesisPatientsPhasePilot ProjectsPneumoniaPopulationPseudomonas aeruginosaPublishingRecoveryResearchResearch InstituteResearch PersonnelResearch Project GrantsResourcesRespiratory CenterRespiratory DiseaseRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsSecureSeriesServicesStrategic PlanningStreptococcus pneumoniaeTechnologyTherapeuticTuberculosisUnited States Department of AgricultureUnited States National Institutes of HealthUniversitiesVaccinesViralburden of illnesscareer developmentcollaborative environmentcollegecombatcostdrug developmentimmunopathologyimprovedindustry partnerinfluenzavirusinter-institutionalmeetingsmembermultidisciplinarynew technologynutritionpreventprogramspublic health prioritiesresearch and developmentresearch facilityrespiratorysuccesssymposiumtenure track
中文摘要
总括
项目摘要
Cobre第三阶段申请寻求支持,以发展可持续的研究设施,以进一步增强
具有全国竞争力的多机构生物医学研究中心-俄克拉荷马州呼吸和医疗中心
传染病(OCRID)。2013年通过科布雷第一阶段赠款建立,并于2018年持续
通过第二期科布雷赠款,OCRID已成为扩大呼吸道传染病的焦点
俄克拉何马州的疾病研究。总部设在俄克拉荷马州立大学(OSU)的OCRID调查人员来自
俄克拉何马州的主要研究机构,包括俄克拉何马州州立大学和俄勒冈州大学的9所学院
俄克拉何马州,以及一个独立的研究机构,俄克拉荷马州医学研究基金会。作为
OSU有史以来第一次收到科布雷奖助金,第一阶段和第二阶段奖产生了革命性的影响
关于俄克拉荷马州呼吸道传染病研究的前景。OCRID从事关键研究
关于呼吸道传染病,重点是流感病毒、呼吸道合胞病毒、呼吸道
细菌和真菌感染,现在是新冠肺炎。OCRID的跨学科项目包括治疗学,
疫苗、诊断、疾病发病机制、营养和生物工程。在成功的基础上
第一阶段和第二阶段获奖,第三阶段Cobre应用的总体目标是进一步维持
通过不断发展成为呼吸道传染病领域的卓越研究中心
在协作环境中的研究设施。目标1将继续开发研究核心设施,包括
并将其转化为可持续的机构核心设施。我们将继续
为Cobre项目和其他调查人员提供核心专业知识和服务,使现有的
核心,开发最先进的新技术,以满足中心调查人员的需求,并扩大
核心服务。完成这些核心设施向自给自足的机构过渡的战略计划
研究设施包括成本回收、机构支持、保障设备、资源和技术。
以及合作赠款、行业合作伙伴和慈善事业。目标2将进一步加强研究
通过试点项目计划和机构间合作,为维持有影响力的研究创造环境。
我们将继续扩大呼吸系统专题领域的多学科调查人员的临界人数
通过培养初级调查人员和将现有调查人员重新定向到呼吸系统
通过试点项目进行传染病研究,并聘用新的终身教职跟踪教职员工
研究是该中心的工作重点。我们还将继续提供研究和职业发展
通过一系列研究研讨会--Work-in-Work,促进俄克拉荷马州的机构间合作
进展和期刊俱乐部会议,一年一度的呼吸道和传染病研究研讨会和
开发多名调查员的补助金申请。
英文摘要
Overall
Project Summary
This CoBRE Phase III application seeks support to develop sustainable research facilities to further enhance a
nationally competitive multi-institutional biomedical research center—the Oklahoma Center for Respiratory and
Infectious Diseases (OCRID). Established in 2013 through the Phase I CoBRE grant and sustained in 2018
through the Phase II CoBRE grant, OCRID has become a focal point for expanding respiratory infectious
disease research in Oklahoma. Based at Oklahoma State University (OSU), OCRID investigators come from
major research institutions across the state of Oklahoma, including 9 colleges at OSU and the University of
Oklahoma, as well as an independent research institute, the Oklahoma Medical Research Foundation. As the
first CoBRE grants ever received by OSU, the Phase I and Phase II awards have had a transformative effect
on the landscape of respiratory infectious disease research in Oklahoma. OCRID engages in critical research
on respiratory infectious diseases with a focus on influenza virus, respiratory syncytial virus, respiratory
bacterial and fungal infections, and now COVID-19. The interdisciplinary projects in OCRID cover therapeutics,
vaccines, diagnostics, disease pathogenesis, nutrition, and bioengineering. Building on the success of the
Phase I and Phase II awards, the overall objective of this Phase III CoBRE application is to further sustain a
research center of excellence in the field of respiratory infectious diseases through the continued development
of research facilities in a collaborative environment. Aim 1 will continue to develop research core facilities with
cutting-edge technologies and transform them into sustainable institutional core facilities. We will continue
to provide core expertise and services to CoBRE projects and other investigators, modernize the established
cores, develop state-of-the-art new technologies to meet the needs of the center investigators, and broaden
core services. A strategic plan to complete the transition of these core facilities into self-sustained institutional
research facilities includes cost recovery, institutional support, securing equipment, resource and technology
and collaborative grants, industry partners and philanthropy. Aim 2 will further enhance the research
environment to sustain impactful research via a pilot projects program and interinstitutional collaborations.
We will continue to expand the critical mass of multidisciplinary investigators in the thematic area of respiratory
infectious diseases by nurturing junior investigators and redirecting established investigators into respiratory
infectious disease research via a pilot projects program and hiring new tenure-track faculty members whose
research is within the focus of the Center. We will also continue to provide research and career development
activities and promote interinstitutional collaborations in Oklahoma via a research seminar series, work-in-
progress and journal club meetings, an annual respiratory and infectious disease research symposium and the
development of multi-investigator grant applications.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Pilot Project Grant Program
-
批准号:10628217
-
项目类别:
-
资助金额:$20.58万
-
财政年份:2023
-
负责人:LIN LIU
-
依托单位:
Administrative Core
-
批准号:10628213
-
项目类别:
-
资助金额:$38.75万
-
财政年份:2023
-
负责人:LIN LIU
-
依托单位:
The Role of Iron In Pulmonary Fibrosis
-
批准号:10838699
-
项目类别:
-
资助金额:$1.71万
-
财政年份:2023
-
负责人:LIN LIU
-
依托单位:
Molecular Biology Core
-
批准号:10628216
-
项目类别:
-
资助金额:$23.94万
-
财政年份:2023
-
负责人:LIN LIU
-
依托单位:
The Role of Iron In Pulmonary Fibrosis
-
批准号:10586471
-
项目类别:
-
资助金额:$46.95万
-
财政年份:2022
-
负责人:LIN LIU
-
依托单位:
Lnc-PINK regulation of innate immunity in lung epithelial cells
-
批准号:10365976
-
项目类别:
-
资助金额:$18.7万
-
财政年份:2021
-
负责人:LIN LIU
-
依托单位:
Oklahoma Center for Respiratory and Infectious Diseases
-
批准号:10215542
-
项目类别:
-
资助金额:$223.38万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Molecular Biology Core
-
批准号:10459262
-
项目类别:
-
资助金额:$24.13万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Oklahoma Center for Respiratory and Infectious Diseases
-
批准号:8686887
-
项目类别:
-
资助金额:$218.87万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Administrative Core
-
批准号:10215543
-
项目类别:
-
资助金额:$119.34万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
miR-101 Control of Pulmonary Fibrosis
-
批准号:9066199
-
项目类别:
-
资助金额:$36.3万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
miR-101 Control of Pulmonary Fibrosis
-
批准号:8579316
-
项目类别:
-
资助金额:$34.56万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
miR-101 Control of Pulmonary Fibrosis
-
批准号:8847381
-
项目类别:
-
资助金额:$35.76万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Oklahoma Center for Respiratory and Infectious Diseases
-
批准号:10459258
-
项目类别:
-
资助金额:$223.62万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Administrative Core
-
批准号:10459259
-
项目类别:
-
资助金额:$89.81万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Oklahoma Center for Respiratory and Infectious Diseases
-
批准号:8432246
-
项目类别:
-
资助金额:$247.66万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Molecular Biology Core
-
批准号:10215546
-
项目类别:
-
资助金额:$32.33万
-
财政年份:2013
-
负责人:LIN LIU
-
依托单位:
Role of MicroRNAs in Bronchopulmonary Dysplasia
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批准号:7844899
-
项目类别:
-
资助金额:$18.46万
-
财政年份:2009
-
负责人:LIN LIU
-
依托单位:
MicroRNA Expression Profiling in Idiopathic Pulmonary Fibrosis
-
批准号:7708091
-
项目类别:
-
资助金额:$7.39万
-
财政年份:2009
-
负责人:LIN LIU
-
依托单位:
MicroRNA Expression Profiling in Idiopathic Pulmonary Fibrosis
-
批准号:7837598
-
项目类别:
-
资助金额:$7.39万
-
财政年份:2009
-
负责人:LIN LIU
-
依托单位:
海外基金