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"Less Pain, Less Fuss, Right Now!" and "Make It Count!"- Multilevel Interventions for Patient, Parent, and Practice to Enhance Provider Recommendations for HPV Vaccination

“减少痛苦，减少烦恼，就现在！”

基本信息

批准号：
10605152
负责人：
JOAN M. GRIFFIN
金额：
$ 57.19万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-04-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10605152
关键词：
12 year old Address Adolescent Anesthetics Antibiotics Area Behavior Therapy Belief Caring Child Clinic Clinical Trials Cluster randomized trial Communities Consent Country Data Dose Education Effectiveness Ensure Evidence based intervention Feedback Female Goals Healthcare Healthcare Systems Healthy People 2020 Human Papilloma Virus Vaccination Human Papilloma Virus Vaccine Human Papilloma Virus-Related Malignant Neoplasm Human Papillomavirus Human papilloma virus infection Individual Institutional Review Boards Intervention Language Malignant Neoplasms Measures Minnesota Modeling Nurses Outcome Pain Parents Patients Performance Pharmaceutical Preparations Policies Politics Population Provider Puerto Rico Recommendation Reporting Rest Risk Risk Factors Sample Size Schools Series Testing Time United States Vaccination Vaccines Visit Work age group clinical practice contextual factors design effective intervention health care service organization health service use immunogenic implementation intervention improved individual patient innovation insight male peer population health pressure prevent primary care clinic primary care practice process evaluation programs recruit social success tailored messaging theories uptake vaccine delivery

项目摘要

PROJECT SUMMARY Our broad, long-term objective is to substantially increase human papillomavirus (HPV) vaccination rates by deploying effective population-health interventions in clinical practices across the United States. As part of this effort, we intend to evaluate two evidence-based interventions with innovative enhancements at six Mayo Clinic primary care practices (PCP) to evaluate their individual and combined impact on rates of HPV vaccination among female and male patients. Aim 1, “Less Pain, Less Fuss, Right Now!”, will test the hypothesis that, as compared to no intervention (current practice), a practice-level intervention utilizing reminder-recalls featuring the availability of non-medication and medication anesthetics, the convenience of nurse-only visits, and the use of persuasive language for early, on-time vaccinations will improve HPV vaccine delivery rates. Aim 2, “Make It Count!”, will test the hypothesis that, as compared to no intervention, a provider- level intervention utilizing a missed-opportunities assessment and feedback intervention applying social pressure (specific peer-performance comparisons) and equipping providers with a strong-recommendation toolkit will improve HPV vaccine delivery rates. Aim 3 will test the hypothesis that simultaneous implementation of interventions targeting individual, interpersonal, and organizational factors will have a synergistic effect on HPV vaccine delivery rates. To accomplish Aims 1-3, we will use a stepped-wedge cluster randomized trial with an integrated process evaluation. The cluster approach prevents cross-contamination between patients or providers as we allocate two separate interventions (Aims 1 and 2) in the six PCPs. The stepped-wedge design, which ensures all practices eventually receive the same set of interventions, permits the single institutional review board overseeing all six PCPs to approve the study without requiring recruitment and consent of individual patients or providers. The stepped-wedge approach also permits us to test the presence of each of the interventions in each PCP, making trial participation more attractive, while also allowing each practice to serve as its own control, reducing the bias due to imbalanced risk factors across practices. The factorial design allows us to use a single trial to test two interventions and assess each individually and in combination. The design also conserves sample size while maintaining power. We will measure the impact separately in females and males, 11-12 years of age for the rates of receipt of HPV vaccine doses due. Rigorously tested, highly effective, population-level interventions are essential if we are to reach the Healthy People 2020 goal for HPV vaccination. The rigor, design, and high likelihood of success of this study will provide key evidence regarding practice- and provider-level interventions to improve HPV vaccination rates. Mayo Clinic's best practices inform not only its own 70 practices across five states but its Mayo Clinic Care Network, which consists of nearly 40 health-care organizations across 26 states and Puerto Rico.

项目总结

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Disparities in vaccination rates in solid organ transplant patients.

DOI：
10.1111/tid.14010
发表时间：
2023-04
期刊：
TRANSPLANT INFECTIOUS DISEASE
影响因子：
2.6
作者：
Felzer, Jamie R.;Finney Rutten, Lila J.;Wi, Chung-Il;LeMahieu, Allison M.;Beam, Elena;Juhn, Young J.;Jacobson, Robert M.;Kennedy, Cassie C.
通讯作者：
Kennedy, Cassie C.

Evidence-Based Strategies for Clinical Organizations to Address COVID-19 Vaccine Hesitancy.

DOI：
10.1016/j.mayocp.2020.12.024
发表时间：
2021-03
期刊：
Mayo Clinic proceedings
影响因子：
8.9
作者：
Finney Rutten LJ;Zhu X;Leppin AL;Ridgeway JL;Swift MD;Griffin JM;St Sauver JL;Virk A;Jacobson RM
通讯作者：
Jacobson RM

Direct-to-adolescent text messaging for vaccine reminders: What will parents permit?

直接向青少年发送疫苗提醒短信：家长会允许什么？

DOI：
10.1016/j.vaccine.2018.03.088
发表时间：
2018
期刊：
Vaccine
影响因子：
5.5
作者：
Roberts,JamesR;Morella,Kristen;Dawley,ErinH;Madden,ChristiA;Jacobson,RobertM;Pope,Charlene;Davis,Boyd;Thompson,David;O'Brien,ElizabethS;Darden,PaulM
通讯作者：
Darden,PaulM

Feasibility of Instituting a Clinical Otolaryngology Human Papillomavirus (HPV) Vaccination Program.

DOI：
10.1002/lary.30130
发表时间：
2023-01
期刊：
LARYNGOSCOPE
影响因子：
2.6
作者：
Palacios, Victoria J.;Merlino, Dante J.;Anderson, Stephanie S.;Yeakel, Sarah R.;Choby, Garret W. G.;Wiedermann, Joshua P.;Moore, Eric J.;O'Byrne, Thomas J.;Jacobson, Robert M.;Van Abel, Kathryn M.
通讯作者：
Van Abel, Kathryn M.

Parent's hesitance about HPV Vaccine: Using the CASE approach to address their concerns.