Novel tools for the imaging of tumor hypoxia using PET

快速生长的肿瘤通常会超过血管为它们提供营养和氧气的能力。这在肿瘤内产生了缺氧的组织区域，并且对放疗和化疗具有高度抗性。使用核医学技术对这些区域进行成像现在对于癌症患者的治疗计划变得重要。该项目旨在改善现有药物的特性，以便更好地选择患者进行特定类型的治疗。

Fast growing tumors often outgrow the ability of blood vessels to properly supply them with nutrients and oxygen. This creates tissue areas within the tumor that are lacking oxygen and are highly resistant to radiotherapy and chemotherapy. Imaging these areas using nuclear medicine techniques has now become important for therapy planning of cancer sufferers. This project aims to improve the properties of the existing agents in order to better select patients for a particular type of treatment.