Novel tools for the imaging of tumor hypoxia using PET

使用 PET 进行肿瘤缺氧成像的新工具

• 批准号: nhmrc : 469002
• 负责人: A/Pr Henri Tochon-Danguy
• 金额: $ 48.53万
• 依托单位: Austin Hospital Medical Research Foundation
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-tools-imaging-using-pet/78178
• 关键词: Novel; tools; imaging; tumor; hypoxia

Fast growing tumors often outgrow the ability of blood vessels to properly supply them with nutrients and oxygen. This creates tissue areas within the tumor that are lacking oxygen and are highly resistant to radiotherapy and chemotherapy. Imaging these areas using nuclear medicine techniques has now become important for therapy planning of cancer sufferers. This project aims to improve the properties of the existing agents in order to better select patients for a particular type of treatment.

快速生长的肿瘤通常会超过血管为它们提供营养和氧气的能力。这在肿瘤内产生了缺氧的组织区域，并且对放疗和化疗具有高度抗性。使用核医学技术对这些区域进行成像现在对于癌症患者的治疗计划变得重要。该项目旨在改善现有药物的特性，以便更好地选择患者进行特定类型的治疗。